CZ20024150A3 - Substituované triazolopyrimidiny - Google Patents

Substituované triazolopyrimidiny Download PDF

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Publication number
CZ20024150A3
CZ20024150A3 CZ20024150A CZ20024150A CZ20024150A3 CZ 20024150 A3 CZ20024150 A3 CZ 20024150A3 CZ 20024150 A CZ20024150 A CZ 20024150A CZ 20024150 A CZ20024150 A CZ 20024150A CZ 20024150 A3 CZ20024150 A3 CZ 20024150A3
Authority
CZ
Czechia
Prior art keywords
chloro
carbon atoms
triazolo
optionally substituted
pyrimidine
Prior art date
Application number
CZ20024150A
Other languages
Czech (cs)
English (en)
Inventor
Paul Carter
Waldemar Pfrengle
Guido Albert
Mark R. Schmitt
Donald R. Kirsch
Jane E. Harris
Cart F. Beyer
Klaus-Juergen Pees
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Publication of CZ20024150A3 publication Critical patent/CZ20024150A3/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CZ20024150A 2000-06-30 2001-06-28 Substituované triazolopyrimidiny CZ20024150A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21558500P 2000-06-30 2000-06-30

Publications (1)

Publication Number Publication Date
CZ20024150A3 true CZ20024150A3 (cs) 2003-09-17

Family

ID=22803554

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20024150A CZ20024150A3 (cs) 2000-06-30 2001-06-28 Substituované triazolopyrimidiny

Country Status (24)

Country Link
US (1) US7329663B2 (enExample)
EP (1) EP1307200A2 (enExample)
JP (1) JP2004502691A (enExample)
KR (1) KR20030013475A (enExample)
CN (1) CN1592624A (enExample)
AR (1) AR034553A1 (enExample)
AU (2) AU2001273062B2 (enExample)
BG (1) BG107277A (enExample)
BR (1) BR0112038A (enExample)
CA (1) CA2413802A1 (enExample)
CZ (1) CZ20024150A3 (enExample)
EA (1) EA006483B1 (enExample)
GE (1) GEP20053688B (enExample)
HK (1) HK1052646A1 (enExample)
HU (1) HUP0300798A3 (enExample)
IL (1) IL152869A0 (enExample)
IN (1) IN2003KO00001A (enExample)
MX (1) MXPA02011913A (enExample)
NO (1) NO20026195L (enExample)
NZ (1) NZ523807A (enExample)
PL (1) PL360027A1 (enExample)
SK (1) SK18412002A3 (enExample)
WO (1) WO2002002563A2 (enExample)
ZA (1) ZA200300793B (enExample)

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MY179926A (en) 2003-12-08 2020-11-19 Wyeth Corp Process for the preparation of tubulin inhibitors
EP1697373A1 (de) * 2003-12-17 2006-09-06 Basf Aktiengesellschaft 6-(2,4,6-trihalogenphenyl)-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bek mpfung von schadpil zen sowie sie enthaltende mittel
WO2005058902A1 (de) * 2003-12-17 2005-06-30 Basf Aktiengesellschaft 6-(2,3,6-trifluorphenyl)-triazolopyrimidine zur bekämpfung von schadpilzen
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CN103360398B (zh) * 2013-07-22 2015-03-25 山东大学 一种三唑并嘧啶类hiv-1逆转录酶抑制剂及其制备方法与应用
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WO2020159942A1 (en) * 2019-01-29 2020-08-06 Tosk, Inc. Pyrazolopyrimidine modulators of ras gtpase
WO2020214537A1 (en) 2019-04-15 2020-10-22 Tosk, Inc. Modulators of ras gtpase
US20230167121A1 (en) * 2020-04-14 2023-06-01 The Trustees Of The University Of Pennsylvania Substituted {1,2,4,} triazolo{1,5-a} pyrimidine compounds and use in stabilizing microtubules
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Also Published As

Publication number Publication date
EA006483B1 (ru) 2005-12-29
US7329663B2 (en) 2008-02-12
IN2003KO00001A (enExample) 2005-12-02
AR034553A1 (es) 2004-03-03
WO2002002563A2 (en) 2002-01-10
JP2004502691A (ja) 2004-01-29
IL152869A0 (en) 2003-06-24
HK1052646A1 (zh) 2003-09-26
NO20026195L (no) 2003-02-27
HUP0300798A3 (en) 2006-02-28
NZ523807A (en) 2004-09-24
NO20026195D0 (no) 2002-12-23
AU7306201A (en) 2002-01-14
EA200300091A1 (ru) 2003-08-28
HUP0300798A2 (hu) 2003-07-28
PL360027A1 (en) 2004-09-06
CA2413802A1 (en) 2002-01-10
CN1592624A (zh) 2005-03-09
ZA200300793B (en) 2004-07-20
BG107277A (bg) 2004-01-30
AU2001273062B2 (en) 2005-11-24
MXPA02011913A (es) 2003-04-22
KR20030013475A (ko) 2003-02-14
WO2002002563A3 (en) 2003-01-03
GEP20053688B (en) 2005-12-12
US20020068744A1 (en) 2002-06-06
SK18412002A3 (sk) 2003-06-03
EP1307200A2 (en) 2003-05-07
BR0112038A (pt) 2003-04-01

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