PL1684763T3 - 6-arylo-7-halogeno-imidazo[1,2-a]pirymidyny jako środki przeciwnowotworowe - Google Patents

6-arylo-7-halogeno-imidazo[1,2-a]pirymidyny jako środki przeciwnowotworowe

Info

Publication number
PL1684763T3
PL1684763T3 PL04784454T PL04784454T PL1684763T3 PL 1684763 T3 PL1684763 T3 PL 1684763T3 PL 04784454 T PL04784454 T PL 04784454T PL 04784454 T PL04784454 T PL 04784454T PL 1684763 T3 PL1684763 T3 PL 1684763T3
Authority
PL
Poland
Prior art keywords
imidazo
halo
aryl
pyrimidines
anticancer agent
Prior art date
Application number
PL04784454T
Other languages
English (en)
Inventor
Nan Zhang
Semiramis Ayral-Kaloustian
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PL1684763T3 publication Critical patent/PL1684763T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL04784454T 2003-09-24 2004-09-17 6-arylo-7-halogeno-imidazo[1,2-a]pirymidyny jako środki przeciwnowotworowe PL1684763T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50548603P 2003-09-24 2003-09-24
PCT/US2004/030595 WO2005030218A1 (en) 2003-09-24 2004-09-17 6-aryl-7-halo-imidazo[1,2-a]pyrimidines as anticancer agent
EP04784454A EP1684763B1 (en) 2003-09-24 2004-09-17 6-aryl-7-halo-imidazo[1,2-a]pyrimidines as anticancer agent

Publications (1)

Publication Number Publication Date
PL1684763T3 true PL1684763T3 (pl) 2008-11-28

Family

ID=34393021

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04784454T PL1684763T3 (pl) 2003-09-24 2004-09-17 6-arylo-7-halogeno-imidazo[1,2-a]pirymidyny jako środki przeciwnowotworowe

Country Status (14)

Country Link
US (2) US7285555B2 (pl)
EP (1) EP1684763B1 (pl)
JP (1) JP4695595B2 (pl)
CN (1) CN100486580C (pl)
AT (1) ATE398452T1 (pl)
AU (1) AU2004275728A1 (pl)
BR (1) BRPI0414778A (pl)
CA (1) CA2537520A1 (pl)
DE (1) DE602004014525D1 (pl)
DK (1) DK1684763T3 (pl)
ES (1) ES2308256T3 (pl)
MX (1) MXPA06002939A (pl)
PL (1) PL1684763T3 (pl)
WO (1) WO2005030218A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000035422A2 (en) * 1998-12-18 2000-06-22 Hadasit Medical Research Services & Development Ltd. Method of administering a compound to multi-drug resistant cells
DK1973545T3 (da) 2005-12-23 2013-02-25 Ariad Pharma Inc Bicykliske heteroarylforbindelser
BRPI0807458A2 (pt) * 2007-01-08 2014-06-03 Basf Se Uso de compostos, agente, semente, método para combater fungos nocivos fitopatogênicos, e, composto
CN107935870A (zh) * 2017-11-09 2018-04-20 华中药业股份有限公司 一种2‑甲氨基‑5‑氯二苯甲酮的合成方法

Family Cites Families (42)

* Cited by examiner, † Cited by third party
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TW224044B (pl) 1991-12-30 1994-05-21 Shell Internat Res Schappej B V
JP2794510B2 (ja) 1992-03-27 1998-09-10 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
IL108747A (en) 1993-03-04 1999-03-12 Shell Int Research Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation
IL108731A (en) 1993-03-04 1997-03-18 Shell Int Research 6, N-DISUBSTITUTED-£1, 2, 4| TRIAZOLO-£1, 5-a| PYRIMIDINE- 7-AMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
RU2147584C1 (ru) 1995-10-27 2000-04-20 Американ Цианамид Компани Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов
US5817663A (en) 1996-10-07 1998-10-06 American Cyanamid Company Pentafluorophenylazolopyrimidines
US5750766A (en) 1997-03-18 1998-05-12 American Cyanamid Company Process for the preparation of arylmalonates
DK0984919T3 (da) 1997-03-18 2003-05-12 Basf Ag Fremgangsmåde til fremstilling af arylmalonater
US5948783A (en) 1997-04-14 1999-09-07 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US6117876A (en) 1997-04-14 2000-09-12 American Cyanamid Company Fungicidal trifluorophenyl-triazolopyrimidines
US6255309B1 (en) 1999-03-19 2001-07-03 American Cyanomid Co. Fungicidal trifluoromethylalkylamino-triazolopyrimidines
TW460476B (en) 1997-04-14 2001-10-21 American Cyanamid Co Fungicidal trifluoromethylalkylamino-triazolopyrimidines
TWI252231B (en) 1997-04-14 2006-04-01 American Cyanamid Co Fungicidal trifluorophenyl-triazolopyrimidines
US5994360A (en) 1997-07-14 1999-11-30 American Cyanamid Company Fungicidal 5-alkyl-triazolopyrimidines
NZ506247A (en) 1998-02-11 2003-03-28 American Cyanamid Co Fungicidal 7-(alkyl, alkenyl, alkadienyl, cycloalkyl, cycloalkenyl or aryl)-[1,2,4]triazolo[1,5-a]pyrimidines
US6020338A (en) 1998-02-11 2000-02-01 American Cyanamid Company Fungicidal 7-alkyl-triazolopyrimidines
JPH11322517A (ja) 1998-03-17 1999-11-24 American Cyanamid Co トリアゾロピリミジン類の効力の増進
US6124301A (en) 1998-03-17 2000-09-26 American Cyanamid Company Enhancement of the efficacy of triazolopyrimidines
US6284762B1 (en) 1998-03-23 2001-09-04 American Cyanamid Company Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
AU752669B2 (en) 1998-03-23 2002-09-26 Basf Aktiengesellschaft Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
US5981534A (en) 1998-09-25 1999-11-09 American Cyanamid Company Fungicidal 6-(2,6-difluoro-4-alkoxyphenyl)-triazolopyrimidines
US6268371B1 (en) 1998-09-10 2001-07-31 American Cyanamid Co. Fungicidal mixtures
US6117865A (en) 1998-09-10 2000-09-12 American Cyanamid Company Fungicidal trifluorophenyl-triazolopyrimidines
US5986135A (en) 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
JP2000103790A (ja) 1998-09-25 2000-04-11 American Cyanamid Co 殺菌・殺カビ性のトリハロフェニル―トリアゾロピリミジン類
US6156925A (en) 1998-09-25 2000-12-05 American Cyanamid Company Process for the preparation of halogenated phenylmaloates
US6242451B1 (en) 1998-09-25 2001-06-05 Klaus-Juergen Pees Fungicidal trihalophenyl-triazolopyrimidines
US5985883A (en) 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trichlorophenyl-triazolopyrimidines
EP1130962B1 (en) 1998-09-25 2004-01-21 Basf Aktiengesellschaft Non-aqueous suspension concentrate
DE69908052T2 (de) 1998-09-25 2003-11-27 Basf Ag Fungizide Mischungen
US6277856B1 (en) 1998-09-25 2001-08-21 American Cynamid Co. Fungicidal mixtures
JP4025468B2 (ja) 1999-07-29 2007-12-19 三井化学株式会社 有機電界発光素子
WO2001035738A2 (en) 1999-11-18 2001-05-25 Basf Corporation Non-aqueous concentrated spreading oil composition
US6559151B2 (en) 2000-05-08 2003-05-06 Basf Aktiengesellschaft 6-(2-trifluoromethyl-phenyl)-triazolopyrimidines
JP2004502691A (ja) * 2000-06-30 2004-01-29 ワイス 抗癌薬としての置換トリアゾロピリミジン
CA2420217A1 (en) 2000-08-25 2002-02-28 Basf Aktiengesellschaft Fungicidal formulation
DE60013188T2 (de) 2000-12-06 2004-12-30 Basf Ag Fungiizide 6-(trifluormethyl-phenyl)-triazolpyrimidine
WO2002067679A1 (en) 2001-02-19 2002-09-06 Basf Aktiengesellschaft Fungicidal mixtures
ATE287405T1 (de) 2001-04-11 2005-02-15 Wyeth Corp 5-halogen-6-phenyl-7-fluoroalkylamino- triazolopyrimidine als fungizide
US7211545B2 (en) * 2001-09-04 2007-05-01 Sumitomo Chemical Company, Limited Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof
AU2003211651A1 (en) * 2002-04-19 2003-11-03 Sumitomo Chemical Company, Limited 5,6-DIPHENYLIMIDAZO(1,2-a)PYRIMIDINE AND BACTERICIDAL COMPOSITION CONTAINING THE SAME

Also Published As

Publication number Publication date
US7285555B2 (en) 2007-10-23
BRPI0414778A (pt) 2006-11-21
US20080255157A1 (en) 2008-10-16
EP1684763B1 (en) 2008-06-18
JP4695595B2 (ja) 2011-06-08
CN1856311A (zh) 2006-11-01
EP1684763A1 (en) 2006-08-02
AU2004275728A1 (en) 2005-04-07
CA2537520A1 (en) 2005-04-07
US7915266B2 (en) 2011-03-29
DK1684763T3 (da) 2008-09-01
US20050065167A1 (en) 2005-03-24
DE602004014525D1 (de) 2008-07-31
ES2308256T3 (es) 2008-12-01
CN100486580C (zh) 2009-05-13
MXPA06002939A (es) 2006-05-31
ATE398452T1 (de) 2008-07-15
WO2005030218A1 (en) 2005-04-07
JP2007506745A (ja) 2007-03-22

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