CY1126069T1 - Προσδιορισμος για αντισωματα ιου jc - Google Patents
Προσδιορισμος για αντισωματα ιου jcInfo
- Publication number
- CY1126069T1 CY1126069T1 CY20221100739T CY221100739T CY1126069T1 CY 1126069 T1 CY1126069 T1 CY 1126069T1 CY 20221100739 T CY20221100739 T CY 20221100739T CY 221100739 T CY221100739 T CY 221100739T CY 1126069 T1 CY1126069 T1 CY 1126069T1
- Authority
- CY
- Cyprus
- Prior art keywords
- sample
- subject
- antibodies
- hpvlp
- jcv
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 241000701460 JC polyomavirus Species 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Η αποκάλυψη αφορά μεθόδους και αντιδραστήρια και ανάλυση δειγμάτων για αντισώματα ιού JC. Αποκαλύπτεται μία μέθοδος που περιλαμβάνει λήψη ενός βιολογικού δείγματος από ένα υποκείμενο (π.χ., πλάσμα, ορός, αίμα, ούρα, ή εγκεφαλονωτιαίο υγρό), επαφή του δείγματος με εξαιρετικά καθαρισμένα virus-like σωματίδια (HPVLPs), υπό συνθήκες κατάλληλες για δέσμευση ενός αντισώματος JCV εντός του δείγματος προς ένα HPVLP και ανίχνευση του επιπέδου δέσμευσης αντισώματος JCV εντός του δείγματος προς ένα HPVLP. Σε μία υλοποίηση, ο ορισμός του επιπέδου αντισωμάτων έναντι JCV στο δείγμα του υποκειμένου παρέχει μία μέθοδο για την ταυτοποίηση κινδύνου PML σε ένα υποκείμενο.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29404810P | 2010-01-11 | 2010-01-11 | |
US31619310P | 2010-03-22 | 2010-03-22 | |
PCT/US2011/020832 WO2011085369A1 (en) | 2010-01-11 | 2011-01-11 | Assay for jc virus antibodies |
EP11732315.4A EP2524060B1 (en) | 2010-01-11 | 2011-01-11 | Assay for jc virus antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1126069T1 true CY1126069T1 (el) | 2023-11-15 |
Family
ID=44305841
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181100251T CY1119972T1 (el) | 2010-01-11 | 2018-02-28 | Προσδιορισμος για αντισωματα ιου jc |
CY20221100739T CY1126069T1 (el) | 2010-01-11 | 2022-11-18 | Προσδιορισμος για αντισωματα ιου jc |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181100251T CY1119972T1 (el) | 2010-01-11 | 2018-02-28 | Προσδιορισμος για αντισωματα ιου jc |
Country Status (27)
Country | Link |
---|---|
US (2) | US9316641B2 (el) |
EP (3) | EP2524060B1 (el) |
JP (2) | JP5946218B2 (el) |
KR (1) | KR101877576B1 (el) |
CN (1) | CN102906278A (el) |
AU (1) | AU2011203815B2 (el) |
BR (1) | BR112012017014B1 (el) |
CA (1) | CA2784137A1 (el) |
CY (2) | CY1119972T1 (el) |
DK (2) | DK2524060T3 (el) |
ES (2) | ES2930469T3 (el) |
FI (1) | FI3339865T5 (el) |
HK (1) | HK1255318A1 (el) |
HR (2) | HRP20221390T1 (el) |
HU (2) | HUE060312T2 (el) |
IN (1) | IN2012DN06139A (el) |
LT (2) | LT3339865T (el) |
ME (1) | ME03026B (el) |
MX (1) | MX341991B (el) |
NO (1) | NO2524060T3 (el) |
NZ (1) | NZ600681A (el) |
PL (2) | PL2524060T3 (el) |
PT (2) | PT3339865T (el) |
RS (2) | RS56977B1 (el) |
SG (2) | SG181653A1 (el) |
SI (2) | SI3339865T1 (el) |
WO (1) | WO2011085369A1 (el) |
Families Citing this family (17)
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CN101351710B (zh) | 2005-04-04 | 2013-06-05 | 生物基因Idecma公司 | 评价对治疗性蛋白质的免疫应答的方法和产品 |
CA2641513C (en) | 2006-02-28 | 2021-09-21 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
KR20080104343A (ko) | 2006-03-03 | 2008-12-02 | 엘란 파마슈티칼스, 인크. | 나탈리주마브로 염증 및 자가면역 질환을 치료하는 방법 |
EP2485762B1 (en) | 2009-10-11 | 2017-12-13 | Biogen MA Inc. | Anti-vla-4 related assays |
AU2011203815B2 (en) | 2010-01-11 | 2015-11-26 | Biogen Ma Inc. | Assay for JC virus antibodies |
US11287423B2 (en) * | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
HUE061244T2 (hu) * | 2011-05-31 | 2023-06-28 | Biogen Ma Inc | A PML kockázat értékelésének módszere |
WO2013087601A2 (en) * | 2011-12-12 | 2013-06-20 | Janssen Diagnostics Bvba | Polyomavirus peptide sequences |
US20130273549A1 (en) * | 2012-04-16 | 2013-10-17 | Board Of Regents, The University Of Texas System | Detection of extracellular jcv micrornas |
US9631243B2 (en) | 2012-06-18 | 2017-04-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for identifying JC virus |
EP2938631B1 (en) * | 2012-12-31 | 2018-12-19 | Neurimmune Holding AG | Recombinant human antibodies for therapy and prevention of polyomavirus-related diseases |
US9949671B2 (en) | 2013-03-13 | 2018-04-24 | Orthoaccel Technologies, Inc. | Diagnostic mouthpieces |
WO2014193804A1 (en) | 2013-05-28 | 2014-12-04 | Biogen Idec Ma Inc. | Method of assessing risk of pml |
WO2015131078A1 (en) * | 2014-02-27 | 2015-09-03 | Biogen Ma Inc. | Method of assessing risk of pml |
MA40985A (fr) | 2014-11-17 | 2017-09-26 | Biogen Ma Inc | Méthodes de traitement de la sclérose en plaques |
IT201600083859A1 (it) * | 2016-08-09 | 2018-02-09 | Univ Degli Studi Di Ferrara | Immunosaggio per l’identificazione di anticorpi contro il virus Polioma JC (JCPyV) mediante l’uso di peptidi sintetici. |
US20210002372A1 (en) * | 2018-03-02 | 2021-01-07 | United States Government As Represented By The Department Of Veterans Affairs | Methods and compositions for treating natalizumab-associated progressive multifocal encephalopathy |
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2011
- 2011-01-11 AU AU2011203815A patent/AU2011203815B2/en active Active
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