IN2012DN06139A - - Google Patents
Info
- Publication number
- IN2012DN06139A IN2012DN06139A IN6139DEN2012A IN2012DN06139A IN 2012DN06139 A IN2012DN06139 A IN 2012DN06139A IN 6139DEN2012 A IN6139DEN2012 A IN 6139DEN2012A IN 2012DN06139 A IN2012DN06139 A IN 2012DN06139A
- Authority
- IN
- India
- Prior art keywords
- sample
- subject
- hpvlp
- level
- jcv
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The disclosure relates to methods and reagents for analyzing samples for the presence of JC virus antibodies. Disclosed is a method that includes obtaining a biological sample from a subject (e.g., plasma, serum, blood, urine, or cerebrospinal fluid), contacting the sample with highly purified viral-like particles (HPVLPs) under conditions suitable for binding of a JCV antibody in the sample to an HPVLP, and detecting the level of JCV antibody binding in the sample to HPVLP. In one embodiment, determining the level of anti-JCV antibodies in the subject sample provides a method of identifying PML risk in a subject.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29404810P | 2010-01-11 | 2010-01-11 | |
US31619310P | 2010-03-22 | 2010-03-22 | |
PCT/US2011/020832 WO2011085369A1 (en) | 2010-01-11 | 2011-01-11 | Assay for jc virus antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN06139A true IN2012DN06139A (en) | 2015-09-18 |
Family
ID=44305841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN6139DEN2012 IN2012DN06139A (en) | 2010-01-11 | 2011-01-11 |
Country Status (27)
Country | Link |
---|---|
US (2) | US9316641B2 (en) |
EP (3) | EP4152004A1 (en) |
JP (2) | JP5946218B2 (en) |
KR (1) | KR101877576B1 (en) |
CN (1) | CN102906278A (en) |
AU (1) | AU2011203815B2 (en) |
BR (1) | BR112012017014B1 (en) |
CA (1) | CA2784137A1 (en) |
CY (2) | CY1119972T1 (en) |
DK (2) | DK3339865T5 (en) |
ES (2) | ES2930469T3 (en) |
FI (1) | FI3339865T5 (en) |
HK (1) | HK1255318A1 (en) |
HR (2) | HRP20221390T1 (en) |
HU (2) | HUE060312T2 (en) |
IN (1) | IN2012DN06139A (en) |
LT (2) | LT2524060T (en) |
ME (1) | ME03026B (en) |
MX (1) | MX341991B (en) |
NO (1) | NO2524060T3 (en) |
NZ (1) | NZ600681A (en) |
PL (2) | PL3339865T3 (en) |
PT (2) | PT3339865T (en) |
RS (2) | RS56977B1 (en) |
SG (2) | SG181653A1 (en) |
SI (2) | SI2524060T1 (en) |
WO (1) | WO2011085369A1 (en) |
Families Citing this family (17)
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LT2645106T (en) | 2005-04-04 | 2017-09-11 | Biogen Ma Inc. | Methods for evaluating an immune response to a therapeutic agent |
WO2007100770A2 (en) | 2006-02-28 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
SG170058A1 (en) | 2006-03-03 | 2011-04-29 | Elan Pharm Inc | Methods of treating inflammatory and autoimmune diseases with natalizumab |
US9377458B2 (en) | 2009-10-11 | 2016-06-28 | Biogen Ma Inc. | Anti-VLA-4 related assays |
CA2784137A1 (en) | 2010-01-11 | 2011-07-14 | Biogen Idec Ma Inc. | Assay for jc virus antibodies |
US11287423B2 (en) * | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
EP2715352B1 (en) * | 2011-05-31 | 2019-04-24 | Biogen MA Inc. | Method of assessing risk of pml |
EP2791162A2 (en) * | 2011-12-12 | 2014-10-22 | Janssen Diagnostics BVBA | Polyomavirus peptide sequences |
US20130273549A1 (en) * | 2012-04-16 | 2013-10-17 | Board Of Regents, The University Of Texas System | Detection of extracellular jcv micrornas |
WO2013192100A1 (en) | 2012-06-18 | 2013-12-27 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods and compositions for detecting jc virus |
US9771413B2 (en) | 2012-12-31 | 2017-09-26 | Neurimmune Holding Ag | Recombinant human antibodies for therapy and prevention of polyomavirus-related diseases |
US9949671B2 (en) | 2013-03-13 | 2018-04-24 | Orthoaccel Technologies, Inc. | Diagnostic mouthpieces |
EP3004334A4 (en) | 2013-05-28 | 2016-12-21 | Biogen Ma Inc | Method of assessing risk of pml |
ES2818823T3 (en) | 2014-02-27 | 2021-04-14 | Biogen Ma Inc | PML risk assessment method |
MA40985A (en) | 2014-11-17 | 2017-09-26 | Biogen Ma Inc | MULTIPLE SCLEROSIS TREATMENT METHODS |
IT201600083859A1 (en) * | 2016-08-09 | 2018-02-09 | Univ Degli Studi Di Ferrara | Immunosage for the identification of antibodies against the Polioma JC virus (JCPyV) through the use of synthetic peptides. |
US20210002372A1 (en) * | 2018-03-02 | 2021-01-07 | United States Government As Represented By The Department Of Veterans Affairs | Methods and compositions for treating natalizumab-associated progressive multifocal encephalopathy |
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2011
- 2011-01-11 CA CA2784137A patent/CA2784137A1/en active Pending
- 2011-01-11 MX MX2012007660A patent/MX341991B/en active IP Right Grant
- 2011-01-11 ES ES17203178T patent/ES2930469T3/en active Active
- 2011-01-11 PT PT172031783T patent/PT3339865T/en unknown
- 2011-01-11 SI SI201131438T patent/SI2524060T1/en unknown
- 2011-01-11 NZ NZ600681A patent/NZ600681A/en unknown
- 2011-01-11 BR BR112012017014-7A patent/BR112012017014B1/en active IP Right Grant
- 2011-01-11 PL PL17203178.3T patent/PL3339865T3/en unknown
- 2011-01-11 US US13/521,311 patent/US9316641B2/en active Active
- 2011-01-11 PL PL11732315T patent/PL2524060T3/en unknown
- 2011-01-11 HR HRP20221390TT patent/HRP20221390T1/en unknown
- 2011-01-11 SI SI201132069T patent/SI3339865T1/en unknown
- 2011-01-11 EP EP22191259.5A patent/EP4152004A1/en active Pending
- 2011-01-11 CN CN2011800133864A patent/CN102906278A/en active Pending
- 2011-01-11 LT LTEP11732315.4T patent/LT2524060T/en unknown
- 2011-01-11 DK DK17203178.3T patent/DK3339865T5/en active
- 2011-01-11 EP EP17203178.3A patent/EP3339865B9/en active Active
- 2011-01-11 EP EP11732315.4A patent/EP2524060B1/en not_active Revoked
- 2011-01-11 RS RS20180245A patent/RS56977B1/en unknown
- 2011-01-11 HU HUE17203178A patent/HUE060312T2/en unknown
- 2011-01-11 NO NO11732315A patent/NO2524060T3/no unknown
- 2011-01-11 JP JP2012548227A patent/JP5946218B2/en active Active
- 2011-01-11 IN IN6139DEN2012 patent/IN2012DN06139A/en unknown
- 2011-01-11 HU HUE11732315A patent/HUE036183T2/en unknown
- 2011-01-11 WO PCT/US2011/020832 patent/WO2011085369A1/en active Application Filing
- 2011-01-11 RS RS20221053A patent/RS63744B1/en unknown
- 2011-01-11 AU AU2011203815A patent/AU2011203815B2/en active Active
- 2011-01-11 PT PT117323154T patent/PT2524060T/en unknown
- 2011-01-11 SG SG2012043154A patent/SG181653A1/en unknown
- 2011-01-11 KR KR1020127019171A patent/KR101877576B1/en active IP Right Grant
- 2011-01-11 DK DK11732315.4T patent/DK2524060T3/en active
- 2011-01-11 SG SG10201500079YA patent/SG10201500079YA/en unknown
- 2011-01-11 LT LTEP17203178.3T patent/LT3339865T/en unknown
- 2011-01-11 ES ES11732315.4T patent/ES2664173T3/en active Active
- 2011-01-11 ME MEP-2018-60A patent/ME03026B/en unknown
- 2011-01-11 FI FIEP17203178.3T patent/FI3339865T5/en active
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2015
- 2015-12-18 JP JP2015246985A patent/JP2016040557A/en not_active Withdrawn
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2016
- 2016-03-08 US US15/063,777 patent/US10444234B2/en active Active
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2018
- 2018-02-27 HR HRP20180356TT patent/HRP20180356T1/en unknown
- 2018-02-28 CY CY20181100251T patent/CY1119972T1/en unknown
- 2018-11-13 HK HK18114454.0A patent/HK1255318A1/en unknown
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2022
- 2022-11-18 CY CY20221100739T patent/CY1126069T1/en unknown
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