NO20083820L - Deteksjon av kreft ved forhoyede nivaer av BCL-2 - Google Patents

Deteksjon av kreft ved forhoyede nivaer av BCL-2

Info

Publication number
NO20083820L
NO20083820L NO20083820A NO20083820A NO20083820L NO 20083820 L NO20083820 L NO 20083820L NO 20083820 A NO20083820 A NO 20083820A NO 20083820 A NO20083820 A NO 20083820A NO 20083820 L NO20083820 L NO 20083820L
Authority
NO
Norway
Prior art keywords
bcl
cancer
detection
binds
protein
Prior art date
Application number
NO20083820A
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English (en)
Inventor
Patricia A Kruk
Original Assignee
Univ South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Univ South Florida filed Critical Univ South Florida
Publication of NO20083820L publication Critical patent/NO20083820L/no

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57449Specifically defined cancers of ovaries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Foreliggende oppfinnelse omfatter en fremgangsmåte for diagnose, prognose og overvåking av kreft, slik som ovariekreft på et tidlig eller sent stadium, i et individ ved å påvise Bcl-2 i en biologisk prøve fra individet, fortrinnsvis en urin- eller blodprøve. Bcl-2 kan måles ved anvendelse av et middel som påviser eller binder seg til Bci-2-protein, eller et middel som påviser eller binder seg til kodende nukleinsyrer, slik som antistoffer som er spesifikt reaktive med Bcl-2-protein eller en del derav. Oppfinnelsen omfatter videre sett for å utføre fremgangsmåtene ifølge oppfinnelsen. Oppfinnelsen omfatter videre en innretning for raskt å påvise Bcl-2 i en kroppsvæske og fremgangsmåter for raskt å måle Bcl-2 i en kroppsvæske.
NO20083820A 2006-02-09 2008-09-08 Deteksjon av kreft ved forhoyede nivaer av BCL-2 NO20083820L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77167706P 2006-02-09 2006-02-09
PCT/US2007/003608 WO2007092627A2 (en) 2006-02-09 2007-02-09 Detection of cancer by elevated levels of bcl-2

Publications (1)

Publication Number Publication Date
NO20083820L true NO20083820L (no) 2008-11-07

Family

ID=38345845

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083820A NO20083820L (no) 2006-02-09 2008-09-08 Deteksjon av kreft ved forhoyede nivaer av BCL-2

Country Status (16)

Country Link
US (4) US8034549B2 (no)
EP (1) EP1996940B1 (no)
JP (1) JP4896994B2 (no)
KR (1) KR20080114689A (no)
CN (1) CN101384903A (no)
AT (1) ATE538386T1 (no)
AU (1) AU2007212278A1 (no)
BR (1) BRPI0707645B8 (no)
CA (1) CA2642051C (no)
IL (1) IL192866A (no)
NO (1) NO20083820L (no)
NZ (1) NZ570008A (no)
RU (1) RU2436098C2 (no)
SG (1) SG169395A1 (no)
WO (1) WO2007092627A2 (no)
ZA (1) ZA200805787B (no)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10533998B2 (en) 2008-07-18 2020-01-14 Bio-Rad Laboratories, Inc. Enzyme quantification
GB0307403D0 (en) * 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
GB0307428D0 (en) * 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7968287B2 (en) * 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2007081386A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use
KR20080114689A (ko) 2006-02-09 2008-12-31 유니버시티 오브 사우스 플로리다 증가된 bcl-2에 의한 암의 발견
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2530167A1 (en) 2006-05-11 2012-12-05 Raindance Technologies, Inc. Microfluidic Devices
EP3399450A1 (en) * 2006-05-18 2018-11-07 Caris MPI, Inc. System and method for determining individualized medical intervention for a disease state
US8768629B2 (en) * 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
US9012390B2 (en) 2006-08-07 2015-04-21 Raindance Technologies, Inc. Fluorocarbon emulsion stabilizing surfactants
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US20100256610A1 (en) * 2007-10-25 2010-10-07 Basil Rigas Apparatus and method of detection and localized treatment of abnormal conditions
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US20110218155A1 (en) * 2008-10-10 2011-09-08 Dana-Farber Cancer Institute, Inc. Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides
EP3415235A1 (en) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation of microfluidic droplets
WO2010115196A1 (en) * 2009-04-03 2010-10-07 Candela Corporation Skin resurfacing at 1930 nm
US9046522B2 (en) * 2009-07-24 2015-06-02 Geadic Biotec, Aie Markers for endometrial cancer
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
CA2779223A1 (en) * 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
WO2011079176A2 (en) 2009-12-23 2011-06-30 Raindance Technologies, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
EP3392349A1 (en) 2010-02-12 2018-10-24 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
EP2622103B2 (en) 2010-09-30 2022-11-16 Bio-Rad Laboratories, Inc. Sandwich assays in droplets
KR102057438B1 (ko) * 2010-11-05 2019-12-20 에이자이 아이엔씨. 엽산 수용체 알파-발현 암에 대한 진단 및 예후 마커로서의 엽산 수용체 알파
EP2673614B1 (en) 2011-02-11 2018-08-01 Raindance Technologies, Inc. Method for forming mixed droplets
EP3736281A1 (en) 2011-02-18 2020-11-11 Bio-Rad Laboratories, Inc. Compositions and methods for molecular labeling
JP2014512803A (ja) * 2011-02-23 2014-05-29 ムドスーレ エルティディ 個人的腫瘍プロファイリング治療のための組成物及び方法
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP2729486B1 (en) 2011-07-09 2017-12-13 The Regents of The University of California Leukemia stem cell targeting ligands and methods of use
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
EP2742358A4 (en) * 2011-09-08 2015-08-12 Univ Ben Gurion METHOD FOR THE DIAGNOSIS OF CANCER
CN104094111B (zh) * 2011-09-22 2017-07-04 斯隆-凯特林纪念癌症中心 检测卵巢癌
CA2853103C (en) * 2011-10-21 2020-01-07 Decimadx, Llc Point-of-care immunoassay for quantitative small analyte detection
WO2013120089A1 (en) 2012-02-10 2013-08-15 Raindance Technologies, Inc. Molecular diagnostic screening assay
EP2844768B1 (en) 2012-04-30 2019-03-13 Raindance Technologies, Inc. Digital analyte analysis
EP2986762B1 (en) 2013-04-19 2019-11-06 Bio-Rad Laboratories, Inc. Digital analyte analysis
NZ716862A (en) * 2013-08-19 2022-05-27 Biontech Diagnostics Gmbh Methods and kits for the molecular subtyping of tumors
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
EP3158085B1 (en) 2014-06-18 2020-12-02 Clear Gene, Inc. Methods for rapid analysis of biological markers
US9810610B2 (en) 2014-09-17 2017-11-07 Hologic, Inc. Method of partial lysis and assay
GB201417281D0 (en) * 2014-09-30 2014-11-12 Ge Healthcare Uk Ltd Methods and devices relating to the detection of oral cancer biomarkers
JP5995117B2 (ja) * 2015-01-26 2016-09-21 国立大学法人 筑波大学 可溶型cd155タンパク質を用いた癌の検出方法
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US11401558B2 (en) 2015-12-18 2022-08-02 Clear Gene, Inc. Methods, compositions, kits and devices for rapid analysis of biological markers
US10998178B2 (en) 2017-08-28 2021-05-04 Purdue Research Foundation Systems and methods for sample analysis using swabs
JP2021530247A (ja) * 2018-07-05 2021-11-11 オベーション ダイアグノスティクス エルエルシー 癌の診断のためのBCl−2抗体とイムノアッセイ
CN109374897B (zh) * 2018-11-22 2021-11-02 大连大学 一种用于肝癌检测的试剂盒
US20210179683A1 (en) * 2019-12-06 2021-06-17 Proteina Co., Ltd. Method of response prediction for bcl2 family protein targeting drug
WO2021216691A1 (en) * 2020-04-21 2021-10-28 Croce Carlo M Methods of detecting and treating cancers characterized by loss of mir15 and mir16 expression
CN111679076A (zh) * 2020-06-15 2020-09-18 吉林医药学院 一种用于检测cyclinD1和BCL-2抗体的检测试剂盒
WO2023239572A1 (en) * 2022-06-01 2023-12-14 Northeastern University Enhanced specificity mass tag dna adductomics

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4381291A (en) 1979-02-23 1983-04-26 Ab Fortia Measurement of free ligands
US4260678A (en) 1979-02-23 1981-04-07 Corning Glass Works Determining creatine kinase isoenzmes via immobilized antibody-isoenzyme complexes
US4343312A (en) 1979-04-16 1982-08-10 Vitafin N.V. Pacemaker output circuit
FR2455743A1 (fr) 1979-05-02 1980-11-28 Goella Laboratoires Procede et dispositif pour le dosage des lipoproteines seriques
US4357311A (en) 1980-10-03 1982-11-02 Warner-Lambert Company Substrate for immunoassay and means of preparing same
US4671958A (en) 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4867973A (en) 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
JPS59500735A (ja) 1983-04-18 1984-04-26 エス・ア−ル・アイ・インタ−ナシヨナル 人間の癌診断のための方法および試験キツト
US4582789A (en) 1984-03-21 1986-04-15 Cetus Corporation Process for labeling nucleic acids using psoralen derivatives
US4617261A (en) 1984-03-21 1986-10-14 Cetus Corporation Process for labeling nucleic acids and hybridization probes
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5015568A (en) * 1986-07-09 1991-05-14 The Wistar Institute Diagnostic methods for detecting lymphomas in humans
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5356817A (en) 1988-06-09 1994-10-18 Yale University Methods for detecting the onset, progression and regression of gynecologic cancers
US5312922A (en) 1992-04-06 1994-05-17 Nordion International Inc. Europium and terbium chelators for time-resolved fluorometric assays
DK0689673T3 (da) * 1993-03-17 1998-02-02 Akzo Nobel Nv Apparat til påvisning af et specifikt reagerende stof
US5539094A (en) * 1993-11-12 1996-07-23 La Jolla Cancer Research Foundation DNA encoding Bcl-2-associated proteins
US5695944A (en) * 1995-05-05 1997-12-09 Thomas Jefferson University Modulation of bcl-2 phosphorylation
US6811995B1 (en) 1996-04-26 2004-11-02 Children's Medical Center Corporation Non-invasive enzyme screen for cancer
US5821082A (en) * 1996-05-23 1998-10-13 St. Louis University Health Sciences Center Anti-proliferation domain of a human Bcl-2 and DNA encoding the same
DE19936618A1 (de) * 1999-08-04 2001-03-15 Monotec Gmbh Diagnostisches Kit und dessen Verwendung
WO2001057060A1 (en) * 2000-02-01 2001-08-09 Human Genome Sciences, Inc. Bcl-2-like polynucleotides, polypeptides, and antibodies
KR100414637B1 (ko) 2000-02-08 2004-01-13 (주)에스제이바이오메드 사람 미토콘드리아 아데닐레이트 키나제 이소자임들에대한 항체와 면역학적 제제 및 심장질환 진단키트
WO2001075177A2 (en) 2000-04-03 2001-10-11 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tumor markers in ovarian cancer
US6492127B2 (en) * 2001-01-23 2002-12-10 Varian, Inc. Lateral flow testing device with on-board chemical reactant
ATE366938T1 (de) * 2001-05-07 2007-08-15 Burnham Inst Verfahren zur bestimmung der prognose von krebspatienten mittels tucan
AU2002309668A1 (en) 2001-05-07 2002-11-18 The Burnham Institute Methods for determining the prognosis for cancer patients using tucan
DK2799555T3 (en) * 2002-03-13 2017-05-22 Genomic Health Inc Gene Expression Profiling in Tumor Tissue Biopsies
KR20030092378A (ko) * 2002-05-29 2003-12-06 박영미 고형암의 진행 정도를 진단하는 방법 및 키트
AU2003243559A1 (en) * 2002-06-13 2003-12-31 Neuropro Technologies, Inc. Apparatus and methods for detecting cerebrospinal fluid
CN1402004A (zh) * 2002-09-27 2003-03-12 江西中德生物工程有限公司 一种免疫层析一步法检测β-肾上腺素激动剂类药物的方法及试纸的制备
US20040137538A1 (en) * 2003-01-10 2004-07-15 Bradford Sherry A. Cancer comprehensive assay kit for identifying cancer protein patterns
US7288383B2 (en) 2003-01-15 2007-10-30 The Brigham And Women's Hospital, Inc. Eosinophil-derived neurotoxin as a marker for ovarian cancer
ES2319320T3 (es) * 2004-09-30 2009-05-06 Quidel Corporation Dispositivos analiticos con vias de flujo primaria y secundaria.
KR20080114689A (ko) 2006-02-09 2008-12-31 유니버시티 오브 사우스 플로리다 증가된 bcl-2에 의한 암의 발견

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CN101384903A (zh) 2009-03-11
NZ570008A (en) 2011-10-28
JP4896994B2 (ja) 2012-03-14
US8034549B2 (en) 2011-10-11
ZA200805787B (en) 2009-05-27
US20080009005A1 (en) 2008-01-10
CA2642051A1 (en) 2007-08-16
US20160258960A1 (en) 2016-09-08
US20190072556A1 (en) 2019-03-07
IL192866A (en) 2013-04-30
RU2008136193A (ru) 2010-03-20
EP1996940A4 (en) 2009-10-21
BRPI0707645B8 (pt) 2021-07-27
ATE538386T1 (de) 2012-01-15
EP1996940B1 (en) 2011-12-21
US20110318763A1 (en) 2011-12-29
CA2642051C (en) 2017-01-24
BRPI0707645B1 (pt) 2019-04-09
WO2007092627A3 (en) 2008-11-13
US11156613B2 (en) 2021-10-26
RU2436098C2 (ru) 2011-12-10
KR20080114689A (ko) 2008-12-31
SG169395A1 (en) 2011-03-30
BRPI0707645A2 (pt) 2011-05-10
JP2009526234A (ja) 2009-07-16
AU2007212278A1 (en) 2007-08-16
EP1996940A2 (en) 2008-12-03
WO2007092627A9 (en) 2007-10-18
WO2007092627A2 (en) 2007-08-16

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