DE60129151D1 - Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) - Google Patents
Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)Info
- Publication number
- DE60129151D1 DE60129151D1 DE60129151T DE60129151T DE60129151D1 DE 60129151 D1 DE60129151 D1 DE 60129151D1 DE 60129151 T DE60129151 T DE 60129151T DE 60129151 T DE60129151 T DE 60129151T DE 60129151 D1 DE60129151 D1 DE 60129151D1
- Authority
- DE
- Germany
- Prior art keywords
- callique
- human
- detecting
- detecting egg
- binds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title 1
- 238000003384 imaging method Methods 0.000 abstract 2
- 206010033128 Ovarian cancer Diseases 0.000 abstract 1
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24378900P | 2000-10-27 | 2000-10-27 | |
US243789P | 2000-10-27 | ||
PCT/CA2001/001505 WO2002035232A2 (en) | 2000-10-27 | 2001-10-26 | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60129151D1 true DE60129151D1 (de) | 2007-08-09 |
DE60129151T2 DE60129151T2 (de) | 2008-03-06 |
Family
ID=22920140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60129151T Expired - Lifetime DE60129151T2 (de) | 2000-10-27 | 2001-10-26 | Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) |
Country Status (9)
Country | Link |
---|---|
US (1) | US20040096915A1 (de) |
EP (1) | EP1330652B1 (de) |
JP (1) | JP2004511810A (de) |
AT (1) | ATE365922T1 (de) |
AU (1) | AU2002213704A1 (de) |
CA (1) | CA2426286A1 (de) |
DE (1) | DE60129151T2 (de) |
ES (1) | ES2287169T3 (de) |
WO (1) | WO2002035232A2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
CA2418422C (en) * | 2000-08-11 | 2011-06-07 | Mount Sinai Hospital | Novel kallikrein gene |
EP1332367A2 (de) * | 2000-11-01 | 2003-08-06 | Mount Sinai Hospital | Nachweis von eierstockkrebs |
WO2002097438A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
KR20040081420A (ko) * | 2001-10-16 | 2004-09-21 | 마운트 시나이 하스피틀 코포레이션 | 난소암의 검출 방법 |
WO2003034068A1 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Localization of disorders associated with kallikreins |
CA2497061A1 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
US20060073525A1 (en) * | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
WO2004029285A2 (en) * | 2002-09-26 | 2004-04-08 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
CA2516591A1 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
CA2516588A1 (en) * | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
US20050106586A1 (en) * | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
CN102989009B (zh) * | 2003-12-31 | 2015-06-03 | 宾夕法尼亚州研究基金会 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
EP1718975A2 (de) * | 2004-02-18 | 2006-11-08 | Bayer HealthCare AG | Diagnostika und therapeutika für mit kallikrein 6 (klk6) in zusammenhang stehende krankheiten |
DE102005004294A1 (de) * | 2005-01-28 | 2006-08-03 | Bayer Healthcare Ag | Auswahl und Bewertung diagnostischer Tests mittels Diskordanzanalysen-Charakteristik (DAC) |
US8329399B2 (en) * | 2006-10-27 | 2012-12-11 | Siu K W Michael | Endometrial biomarkers |
WO2009126455A1 (en) * | 2008-04-09 | 2009-10-15 | Smiths Detection Inc. | Multi-dimensional spectral analysis for improved identification and confirmation of radioactive isotopes |
US7851230B2 (en) * | 2008-04-14 | 2010-12-14 | Chang Gung Memorial Hospital | Stress-induced phosphoprotein 1 as a biomarker for the detection of human ovarian cancers and endometriosis |
US20140148348A1 (en) | 2010-01-13 | 2014-05-29 | Christine Kuslich | Dectection of gastrointestinal disorders |
JP5808349B2 (ja) | 2010-03-01 | 2015-11-10 | カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー | セラノーシスのためのバイオマーカー |
BR112012025593A2 (pt) | 2010-04-06 | 2019-06-25 | Caris Life Sciences Luxembourg Holdings | biomarcadores em circulação para doença |
WO2012174569A2 (en) * | 2011-06-17 | 2012-12-20 | The Board Of Trustees Of The University Of Arkansas | New markers for early diagnosis of ovarian cancer, monitoring during therapy, and new therapy options during and after chematherapy |
CN103675278A (zh) * | 2013-11-19 | 2014-03-26 | 上海裕隆医学检验所股份有限公司 | 一种糖链抗原125定量检测试剂盒及其应用 |
CU20170052A7 (es) | 2014-10-14 | 2017-11-07 | Dana Farber Cancer Inst Inc | Moléculas de anticuerpo que se unen a pd-l1 |
KR20210111254A (ko) | 2018-11-30 | 2021-09-10 | 캐리스 엠피아이, 아이엔씨. | 차세대 분자 프로파일링 |
WO2021112918A1 (en) | 2019-12-02 | 2021-06-10 | Caris Mpi, Inc. | Pan-cancer platinum response predictor |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776427A (en) * | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
IL105793A0 (en) * | 1992-05-28 | 1993-09-22 | Lilly Co Eli | Protease and related dna compounds |
AU4480797A (en) * | 1996-09-13 | 1998-04-02 | Dana-Farber Cancer Institute | Protease m, a novel serine protease |
US6268165B1 (en) * | 1997-03-19 | 2001-07-31 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
US6294344B1 (en) * | 1997-03-19 | 2001-09-25 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
WO1998041656A1 (en) * | 1997-03-19 | 1998-09-24 | The Board Of Trustees Of The University Of Arkansas | Compositions and method for the early diagnosis of ovarian cancer |
US6870027B2 (en) * | 1997-03-19 | 2005-03-22 | O'brien Timothy J. | Methods for the early diagnosis of ovarian cancer |
US6316213B1 (en) * | 1997-03-19 | 2001-11-13 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian, breast and lung cancer |
AU755340B2 (en) * | 1998-07-02 | 2002-12-12 | Fuso Pharmaceutical Industries, Ltd. | Serine protease-specific monoclonal antibody and utilization thereof |
US6942978B1 (en) * | 1999-03-03 | 2005-09-13 | The Board Of Trustees Of The University Of Arkansas | Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof |
US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
US7935531B2 (en) * | 2000-02-22 | 2011-05-03 | Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
CA2418422C (en) * | 2000-08-11 | 2011-06-07 | Mount Sinai Hospital | Novel kallikrein gene |
CA2360219A1 (en) * | 2000-10-27 | 2002-04-27 | Mount Sinai Hospital | Method for detecting alzheimer's disease |
WO2002097438A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
KR20040081420A (ko) * | 2001-10-16 | 2004-09-21 | 마운트 시나이 하스피틀 코포레이션 | 난소암의 검출 방법 |
AU2003213960A1 (en) * | 2002-04-04 | 2003-10-20 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
US20040015745A1 (en) * | 2002-07-22 | 2004-01-22 | Finisar Corporation | Scalable socketed testing tool |
CA2497061A1 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
US20060073525A1 (en) * | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
WO2004029285A2 (en) * | 2002-09-26 | 2004-04-08 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
CA2516591A1 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
CA2516588A1 (en) * | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
US20050106586A1 (en) * | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
-
2001
- 2001-10-26 JP JP2002538164A patent/JP2004511810A/ja active Pending
- 2001-10-26 ES ES01982003T patent/ES2287169T3/es not_active Expired - Lifetime
- 2001-10-26 WO PCT/CA2001/001505 patent/WO2002035232A2/en active IP Right Grant
- 2001-10-26 AT AT01982003T patent/ATE365922T1/de not_active IP Right Cessation
- 2001-10-26 US US10/399,013 patent/US20040096915A1/en not_active Abandoned
- 2001-10-26 DE DE60129151T patent/DE60129151T2/de not_active Expired - Lifetime
- 2001-10-26 EP EP01982003A patent/EP1330652B1/de not_active Expired - Lifetime
- 2001-10-26 CA CA002426286A patent/CA2426286A1/en not_active Abandoned
- 2001-10-26 AU AU2002213704A patent/AU2002213704A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1330652A2 (de) | 2003-07-30 |
DE60129151T2 (de) | 2008-03-06 |
US20040096915A1 (en) | 2004-05-20 |
ES2287169T3 (es) | 2007-12-16 |
EP1330652B1 (de) | 2007-06-27 |
ATE365922T1 (de) | 2007-07-15 |
WO2002035232A2 (en) | 2002-05-02 |
AU2002213704A1 (en) | 2002-05-06 |
CA2426286A1 (en) | 2002-05-02 |
JP2004511810A (ja) | 2004-04-15 |
WO2002035232A3 (en) | 2002-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |