EP1330652A2 - Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) - Google Patents
Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)Info
- Publication number
- EP1330652A2 EP1330652A2 EP20010982003 EP01982003A EP1330652A2 EP 1330652 A2 EP1330652 A2 EP 1330652A2 EP 20010982003 EP20010982003 EP 20010982003 EP 01982003 A EP01982003 A EP 01982003A EP 1330652 A2 EP1330652 A2 EP 1330652A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- antibody
- ovarian cancer
- kallikrein
- tumor
- patients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US24378900P | 2000-10-27 | 2000-10-27 | |
| US243789P | 2000-10-27 | ||
| PCT/CA2001/001505 WO2002035232A2 (en) | 2000-10-27 | 2001-10-26 | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1330652A2 true EP1330652A2 (de) | 2003-07-30 |
| EP1330652B1 EP1330652B1 (de) | 2007-06-27 |
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| EP01982003A Expired - Lifetime EP1330652B1 (de) | 2000-10-27 | 2001-10-26 | Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) |
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| US (1) | US20040096915A1 (de) |
| EP (1) | EP1330652B1 (de) |
| JP (1) | JP2004511810A (de) |
| AT (1) | ATE365922T1 (de) |
| AU (1) | AU2002213704A1 (de) |
| CA (1) | CA2426286A1 (de) |
| DE (1) | DE60129151T2 (de) |
| ES (1) | ES2287169T3 (de) |
| WO (1) | WO2002035232A2 (de) |
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| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| ES2266245T3 (es) * | 2000-08-11 | 2007-03-01 | Mount Sinai Hospital | Gen de la calicreina. |
| WO2002037112A2 (en) * | 2000-11-01 | 2002-05-10 | Mount Sinai Hospital | Detection of ovarian cancer |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| JP2005505303A (ja) * | 2001-10-16 | 2005-02-24 | マウント・サイナイ・ホスピタル | 卵巣癌の検出方法 |
| WO2003034068A1 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Localization of disorders associated with kallikreins |
| WO2004021008A2 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| AU2003266038A1 (en) * | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| EP1546728A2 (de) * | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Verfahren zum nachweis von endokrinem krebs |
| US20060134120A1 (en) * | 2003-02-26 | 2006-06-22 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20060141471A1 (en) * | 2003-02-27 | 2006-06-29 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) * | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
| JP4682152B2 (ja) * | 2003-12-31 | 2011-05-11 | ザ・ペン・ステート・リサーチ・ファンデーション | 卵巣がんの化学療法に対する抵抗性を予測および克服するための方法ならびに結腸がんの発生を予測するための方法 |
| EP1718975A2 (de) * | 2004-02-18 | 2006-11-08 | Bayer HealthCare AG | Diagnostika und therapeutika für mit kallikrein 6 (klk6) in zusammenhang stehende krankheiten |
| DE102005004294A1 (de) * | 2005-01-28 | 2006-08-03 | Bayer Healthcare Ag | Auswahl und Bewertung diagnostischer Tests mittels Diskordanzanalysen-Charakteristik (DAC) |
| WO2008049239A1 (en) * | 2006-10-27 | 2008-05-02 | Mount Sinai Hospital | Endometrial biomarkers |
| EP2271917A1 (de) * | 2008-04-09 | 2011-01-12 | Smiths Detection Inc. | Mehrdimensionale spektralanalyse zur verbesserten identifikation und bestätigung von radioaktiven isotopen |
| US7851230B2 (en) * | 2008-04-14 | 2010-12-14 | Chang Gung Memorial Hospital | Stress-induced phosphoprotein 1 as a biomarker for the detection of human ovarian cancers and endometriosis |
| CA2787027A1 (en) | 2010-01-13 | 2011-07-21 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Detection of gastrointestinal disorders |
| CA2791905A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Biomarkers for theranostics |
| AU2011237669B2 (en) | 2010-04-06 | 2016-09-08 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for disease |
| EP2721417A4 (de) * | 2011-06-17 | 2015-05-06 | Univ Arkansas | Neue marker zur frühdiagnose von eierstockkrebs, überwachung während der entsprechenden therapie und neue therapieoptionen während und nach der entsprechenden chemotherapie |
| CN103675278A (zh) * | 2013-11-19 | 2014-03-26 | 上海裕隆医学检验所股份有限公司 | 一种糖链抗原125定量检测试剂盒及其应用 |
| CU20170052A7 (es) | 2014-10-14 | 2017-11-07 | Dana Farber Cancer Inst Inc | Moléculas de anticuerpo que se unen a pd-l1 |
| MX2021006234A (es) | 2018-11-30 | 2021-09-10 | Caris Mpi Inc | Perfilado molecular de proxima generacion. |
| EP4069865A4 (de) | 2019-12-02 | 2023-12-20 | Caris MPI, Inc. | Platinresistenztest für pan-krebs |
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| US5776427A (en) * | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
| IL105793A0 (en) * | 1992-05-28 | 1993-09-22 | Lilly Co Eli | Protease and related dna compounds |
| WO1998011238A2 (en) * | 1996-09-13 | 1998-03-19 | Dana-Farber Cancer Institute | Protease m, a novel serine protease |
| US6870027B2 (en) * | 1997-03-19 | 2005-03-22 | O'brien Timothy J. | Methods for the early diagnosis of ovarian cancer |
| US6268165B1 (en) * | 1997-03-19 | 2001-07-31 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
| WO1998041656A1 (en) * | 1997-03-19 | 1998-09-24 | The Board Of Trustees Of The University Of Arkansas | Compositions and method for the early diagnosis of ovarian cancer |
| US6316213B1 (en) * | 1997-03-19 | 2001-11-13 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian, breast and lung cancer |
| US6294344B1 (en) * | 1997-03-19 | 2001-09-25 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
| DK1092767T3 (da) * | 1998-07-02 | 2006-11-27 | Fuso Pharmaceutical Ind | Serinproteasespecifikke monoklonale antistoffer og anvendelse deraf |
| US6942978B1 (en) * | 1999-03-03 | 2005-09-13 | The Board Of Trustees Of The University Of Arkansas | Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof |
| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US7935531B2 (en) * | 2000-02-22 | 2011-05-03 | Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
| ES2266245T3 (es) * | 2000-08-11 | 2007-03-01 | Mount Sinai Hospital | Gen de la calicreina. |
| CA2360219A1 (en) * | 2000-10-27 | 2002-04-27 | Mount Sinai Hospital | Method for detecting alzheimer's disease |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| JP2005505303A (ja) * | 2001-10-16 | 2005-02-24 | マウント・サイナイ・ホスピタル | 卵巣癌の検出方法 |
| CA2481093A1 (en) * | 2002-04-04 | 2003-10-16 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| US20040015745A1 (en) * | 2002-07-22 | 2004-01-22 | Finisar Corporation | Scalable socketed testing tool |
| AU2003266038A1 (en) * | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| WO2004021008A2 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| EP1546728A2 (de) * | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Verfahren zum nachweis von endokrinem krebs |
| US20060134120A1 (en) * | 2003-02-26 | 2006-06-22 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20060141471A1 (en) * | 2003-02-27 | 2006-06-29 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) * | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
-
2001
- 2001-10-26 AU AU2002213704A patent/AU2002213704A1/en not_active Abandoned
- 2001-10-26 JP JP2002538164A patent/JP2004511810A/ja active Pending
- 2001-10-26 US US10/399,013 patent/US20040096915A1/en not_active Abandoned
- 2001-10-26 CA CA002426286A patent/CA2426286A1/en not_active Abandoned
- 2001-10-26 AT AT01982003T patent/ATE365922T1/de not_active IP Right Cessation
- 2001-10-26 ES ES01982003T patent/ES2287169T3/es not_active Expired - Lifetime
- 2001-10-26 WO PCT/CA2001/001505 patent/WO2002035232A2/en active IP Right Grant
- 2001-10-26 EP EP01982003A patent/EP1330652B1/de not_active Expired - Lifetime
- 2001-10-26 DE DE60129151T patent/DE60129151T2/de not_active Expired - Lifetime
Non-Patent Citations (1)
| Title |
|---|
| See references of WO0235232A3 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20040096915A1 (en) | 2004-05-20 |
| WO2002035232A3 (en) | 2002-09-26 |
| DE60129151T2 (de) | 2008-03-06 |
| WO2002035232A2 (en) | 2002-05-02 |
| CA2426286A1 (en) | 2002-05-02 |
| ES2287169T3 (es) | 2007-12-16 |
| JP2004511810A (ja) | 2004-04-15 |
| AU2002213704A1 (en) | 2002-05-06 |
| DE60129151D1 (de) | 2007-08-09 |
| ATE365922T1 (de) | 2007-07-15 |
| EP1330652B1 (de) | 2007-06-27 |
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