CY1121372T1 - Μεθοδος για την παρασκευη καθαρισμενων ανσαμιτοκινων - Google Patents

Μεθοδος για την παρασκευη καθαρισμενων ανσαμιτοκινων

Info

Publication number
CY1121372T1
CY1121372T1 CY20191100195T CY191100195T CY1121372T1 CY 1121372 T1 CY1121372 T1 CY 1121372T1 CY 20191100195 T CY20191100195 T CY 20191100195T CY 191100195 T CY191100195 T CY 191100195T CY 1121372 T1 CY1121372 T1 CY 1121372T1
Authority
CY
Cyprus
Prior art keywords
ansamitokines
purified
preparation
insamitokines
insamitocin
Prior art date
Application number
CY20191100195T
Other languages
Greek (el)
English (en)
Inventor
Wayne C. Widdison
Original Assignee
Immunogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36692550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1121372(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen, Inc. filed Critical Immunogen, Inc.
Publication of CY1121372T1 publication Critical patent/CY1121372T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CY20191100195T 2005-01-19 2019-02-13 Μεθοδος για την παρασκευη καθαρισμενων ανσαμιτοκινων CY1121372T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/037,104 US7432088B2 (en) 2003-05-08 2005-01-19 Methods for the production of ansamitocins
EP05853651A EP1838863A4 (en) 2005-01-19 2005-12-12 PROCESS FOR THE PREPARATION OF ANSAMITOCINES
PCT/US2005/044783 WO2006078368A1 (en) 2005-01-19 2005-12-12 Methods for the production of ansamitocins

Publications (1)

Publication Number Publication Date
CY1121372T1 true CY1121372T1 (el) 2020-05-29

Family

ID=36692550

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100195T CY1121372T1 (el) 2005-01-19 2019-02-13 Μεθοδος για την παρασκευη καθαρισμενων ανσαμιτοκινων

Country Status (27)

Country Link
US (1) US7432088B2 (enExample)
EP (2) EP2514828B1 (enExample)
JP (1) JP5106120B2 (enExample)
KR (3) KR20120099734A (enExample)
CN (2) CN101103120A (enExample)
AU (1) AU2005325166B2 (enExample)
BR (1) BRPI0519624B8 (enExample)
CA (2) CA2595024C (enExample)
CR (1) CR9228A (enExample)
CY (1) CY1121372T1 (enExample)
DK (1) DK2514828T3 (enExample)
EA (1) EA012524B1 (enExample)
ES (1) ES2710875T3 (enExample)
HK (1) HK1211985A1 (enExample)
HU (1) HUE042312T2 (enExample)
IL (2) IL183918A (enExample)
LT (1) LT2514828T (enExample)
MX (1) MX2007008069A (enExample)
NO (1) NO342876B1 (enExample)
NZ (2) NZ583446A (enExample)
PL (1) PL2514828T3 (enExample)
PT (1) PT2514828T (enExample)
SG (1) SG158905A1 (enExample)
SI (1) SI2514828T1 (enExample)
TR (1) TR201901647T4 (enExample)
WO (1) WO2006078368A1 (enExample)
ZA (1) ZA200704918B (enExample)

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CN101711284A (zh) 2007-01-25 2010-05-19 达娜-法勃肿瘤研究所 抗egfr抗体在治疗egfr突变体介导的疾病中的用途
ES2542152T3 (es) 2007-03-15 2015-07-31 Ludwig Institute For Cancer Research Ltd. Método de tratamiento que emplea anticuerpos de EGFR e inhibidores de Src y formulaciones relacionadas
JP5469600B2 (ja) 2007-07-16 2014-04-16 ジェネンテック， インコーポレイテッド 抗ＣＤ７９ｂ抗体及びイムノコンジュゲートとその使用方法
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UA106586C2 (uk) 2008-01-31 2014-09-25 Дженентек, Інк. Анти-cd79b антитіла, і імунокон'югати та способи їх застосування
KR20160125535A (ko) 2008-03-18 2016-10-31 제넨테크, 인크. 항-ｈｅｒ２ 항체-약물 접합체와 화학요법제의 병용물, 및 사용 방법
CN101319241B (zh) * 2008-07-17 2011-03-30 上海交通大学 安丝菌素的固体发酵方法
BRPI1012676A2 (pt) 2009-04-01 2016-04-05 Genentech Inc anticorpos anti-fcrh5 e imunoconjugados e métodos de uso
AR079256A1 (es) 2009-12-04 2012-01-04 Genentech Inc Metodo para el tratamiento del cancer de mama metastasico con trastuzumab-mcc-dm1
CN101921817A (zh) * 2010-09-07 2010-12-22 上海交通大学 安莎霉素发酵产量提高方法
CA2816426A1 (en) 2010-11-17 2012-06-07 Genentech, Inc. Alaninyl maytansinol antibody conjugates
US8852435B2 (en) * 2011-11-29 2014-10-07 Therapeutics Proteins International, LLC Purification and separation treatment assembly (PASTA) for biological products
CN103255184B (zh) * 2012-02-15 2016-01-27 百奥泰生物科技(广州)有限公司 生产安丝菌素的发酵培养基
CN103805648B (zh) * 2012-11-13 2017-09-15 百奥泰生物科技(广州)有限公司 高产安丝菌素发酵工艺
US10208125B2 (en) 2013-07-15 2019-02-19 University of Pittsburgh—of the Commonwealth System of Higher Education Anti-mucin 1 binding agents and uses thereof
TWI541022B (zh) 2013-12-18 2016-07-11 應克隆公司 針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法
TW201711702A (zh) 2015-06-04 2017-04-01 應克隆公司 使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法
CN113607945B (zh) 2015-07-07 2025-01-28 豪夫迈·罗氏有限公司 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法
CN105907681B (zh) * 2016-05-30 2019-11-19 苏州康聚生物科技有限公司 一种高产安丝菌素p-3的突变株及安丝菌素p-3的制备方法
CN110234348B (zh) 2016-12-16 2024-06-25 蓝鳍生物医药公司 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法
CN108276427A (zh) * 2018-01-14 2018-07-13 常州大学 一种安丝菌素p-3的提取与分离纯化方法
CN108330113B (zh) * 2018-03-08 2019-05-28 山东省医药生物技术研究中心（山东省病毒研究所） 一株高底物专一性酰基转移酶的珍贵束丝放线菌及其应用
CN113444106A (zh) * 2020-03-25 2021-09-28 重庆乾泰生物医药有限公司 一种高纯度安丝菌素的制备方法
CN112630368A (zh) * 2020-12-18 2021-04-09 卓和药业集团有限公司 安丝菌素含量的高效液相色谱检测分析方法
CN117597450A (zh) * 2021-06-18 2024-02-23 杭州中美华东制药有限公司 安丝菌素p-3的提纯方法
CN115477658A (zh) * 2022-10-12 2022-12-16 道中道（菏泽）制药有限公司 一种有效降低安丝菌素p-3杂质的结晶方法

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Also Published As

Publication number Publication date
EP2514828A3 (en) 2013-07-03
ZA200704918B (en) 2008-11-26
CA2595024A1 (en) 2006-07-27
HUE042312T2 (hu) 2019-06-28
EA012524B1 (ru) 2009-10-30
CA2834033A1 (en) 2006-07-27
JP2008526267A (ja) 2008-07-24
JP5106120B2 (ja) 2012-12-26
PT2514828T (pt) 2019-02-15
NO342876B1 (no) 2018-08-20
IL183918A0 (en) 2007-10-31
BRPI0519624B1 (pt) 2021-01-19
CN104745655A (zh) 2015-07-01
CN101103120A (zh) 2008-01-09
BRPI0519624B8 (pt) 2021-05-25
CR9228A (es) 2008-03-31
TR201901647T4 (tr) 2019-02-21
KR20120099734A (ko) 2012-09-11
DK2514828T3 (en) 2019-03-11
AU2005325166B2 (en) 2012-02-02
MX2007008069A (es) 2007-08-21
PL2514828T3 (pl) 2019-04-30
CA2595024C (en) 2014-02-04
SI2514828T1 (sl) 2019-03-29
WO2006078368A1 (en) 2006-07-27
HK1211985A1 (en) 2016-06-03
LT2514828T (lt) 2019-02-25
KR20130051019A (ko) 2013-05-16
ES2710875T3 (es) 2019-04-29
EP1838863A1 (en) 2007-10-03
IL215686A0 (en) 2011-11-30
CA2834033C (en) 2017-01-24
KR20070099576A (ko) 2007-10-09
EP2514828A2 (en) 2012-10-24
EP1838863A4 (en) 2011-10-05
EA200701310A1 (ru) 2008-06-30
US7432088B2 (en) 2008-10-07
NO20074222L (no) 2007-10-18
KR101515873B1 (ko) 2015-04-29
IL183918A (en) 2013-07-31
NZ555437A (en) 2010-04-30
IL215686A (en) 2013-07-31
BRPI0519624A2 (pt) 2009-02-25
AU2005325166A1 (en) 2006-07-27
NZ583446A (en) 2011-08-26
EP2514828B1 (en) 2018-11-14
SG158905A1 (en) 2010-02-26
US20050170475A1 (en) 2005-08-04

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