ZA200704918B - Methods for the production of ansamitocins - Google Patents

Methods for the production of ansamitocins

Info

Publication number
ZA200704918B
ZA200704918B ZA200704918A ZA200704918A ZA200704918B ZA 200704918 B ZA200704918 B ZA 200704918B ZA 200704918 A ZA200704918 A ZA 200704918A ZA 200704918 A ZA200704918 A ZA 200704918A ZA 200704918 B ZA200704918 B ZA 200704918B
Authority
ZA
South Africa
Prior art keywords
ansamitocins
production
methods
Prior art date
Application number
ZA200704918A
Other languages
English (en)
Inventor
Kuo Cynthia
Graham S Byng
Wayne C Widdiwon
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36692550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200704918(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of ZA200704918B publication Critical patent/ZA200704918B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200704918A 2005-01-19 2005-12-12 Methods for the production of ansamitocins ZA200704918B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/037,104 US7432088B2 (en) 2003-05-08 2005-01-19 Methods for the production of ansamitocins

Publications (1)

Publication Number Publication Date
ZA200704918B true ZA200704918B (en) 2008-11-26

Family

ID=36692550

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200704918A ZA200704918B (en) 2005-01-19 2005-12-12 Methods for the production of ansamitocins

Country Status (27)

Country Link
US (1) US7432088B2 (enExample)
EP (2) EP2514828B1 (enExample)
JP (1) JP5106120B2 (enExample)
KR (3) KR20120099734A (enExample)
CN (2) CN104745655A (enExample)
AU (1) AU2005325166B2 (enExample)
BR (1) BRPI0519624B8 (enExample)
CA (2) CA2834033C (enExample)
CR (1) CR9228A (enExample)
CY (1) CY1121372T1 (enExample)
DK (1) DK2514828T3 (enExample)
EA (1) EA012524B1 (enExample)
ES (1) ES2710875T3 (enExample)
HK (1) HK1211985A1 (enExample)
HU (1) HUE042312T2 (enExample)
IL (2) IL183918A (enExample)
LT (1) LT2514828T (enExample)
MX (1) MX2007008069A (enExample)
NO (1) NO342876B1 (enExample)
NZ (2) NZ555437A (enExample)
PL (1) PL2514828T3 (enExample)
PT (1) PT2514828T (enExample)
SG (1) SG158905A1 (enExample)
SI (1) SI2514828T1 (enExample)
TR (1) TR201901647T4 (enExample)
WO (1) WO2006078368A1 (enExample)
ZA (1) ZA200704918B (enExample)

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CN101309739A (zh) * 2005-10-07 2008-11-19 斯图尔德环境咨询有限公司 用磁性载体去除试剂的方法
US20070135629A1 (en) * 2005-12-08 2007-06-14 Millennium Pharmaceuticals, Inc. Isolation of ansamitocins
US20080023046A1 (en) * 2006-07-10 2008-01-31 Ermenegildo Restelli Apparatus for the separation of a resin from a reaction mixture
CN100420754C (zh) * 2006-10-26 2008-09-24 浙江海正药业股份有限公司 一种制备蒽莎姆菌素的方法
CN104013956B (zh) 2007-01-25 2018-12-18 达娜-法勃肿瘤研究所公司 抗egfr抗体在治疗egfr突变体介导的疾病中的用途
CA2680854C (en) 2007-03-15 2017-02-14 Ludwig Institute For Cancer Research Treatment method using egfr antibodies and src inhibitors and related formulations
CN106432496B (zh) 2007-07-16 2020-02-07 健泰科生物技术公司 抗cd79b抗体和免疫偶联物及使用方法
AR067543A1 (es) 2007-07-16 2009-10-14 Genentech Inc Anticuerpos anti-cd79b e inmunoconjugados humanizados y metodos de uso
CN108424454B (zh) 2007-08-14 2022-05-31 路德维格癌症研究所有限公司 靶向egf受体的单克隆抗体175及其衍生物和用途
EP2247620B1 (en) 2008-01-31 2016-05-18 Genentech, Inc. Anti-cd79b antibodies and immunoconjugates and methods of use
HUE035182T2 (hu) 2008-03-18 2018-05-02 Genentech Inc Anti-HER2 antitest-hatóanyag-konjugátum és pertuzumab kombinációi
CN101319241B (zh) * 2008-07-17 2011-03-30 上海交通大学 安丝菌素的固体发酵方法
US8466260B2 (en) 2009-04-01 2013-06-18 Genentech, Inc. Anti-FcRH5 antibodies and immunoconjugates and methods of use
TW201129380A (en) 2009-12-04 2011-09-01 Genentech Inc Methods of treating metastatic breast cancer with trastuzumab-MCC-DM1
CN101921817A (zh) * 2010-09-07 2010-12-22 上海交通大学 安莎霉素发酵产量提高方法
CA2816426A1 (en) 2010-11-17 2012-06-07 Genentech, Inc. Alaninyl maytansinol antibody conjugates
US8852435B2 (en) * 2011-11-29 2014-10-07 Therapeutics Proteins International, LLC Purification and separation treatment assembly (PASTA) for biological products
CN103255184B (zh) * 2012-02-15 2016-01-27 百奥泰生物科技(广州)有限公司 生产安丝菌素的发酵培养基
CN103805648B (zh) * 2012-11-13 2017-09-15 百奥泰生物科技(广州)有限公司 高产安丝菌素发酵工艺
US10208125B2 (en) 2013-07-15 2019-02-19 University of Pittsburgh—of the Commonwealth System of Higher Education Anti-mucin 1 binding agents and uses thereof
TWI541022B (zh) 2013-12-18 2016-07-11 應克隆公司 針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法
TW201711702A (zh) 2015-06-04 2017-04-01 應克隆公司 使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法
HRP20191019T1 (hr) 2015-07-07 2019-09-06 F. Hoffmann - La Roche Ag Kombinacijska terapija konjugatom protutijela i lijeka anti-her2 i inhibitorom bcl-2
CN105907681B (zh) * 2016-05-30 2019-11-19 苏州康聚生物科技有限公司 一种高产安丝菌素p-3的突变株及安丝菌素p-3的制备方法
WO2018112334A1 (en) 2016-12-16 2018-06-21 Bluefin Biomedicine, Inc. Anti-cub domain-containing protein 1 (cdcp1) antibodies, antibody drug conjugates, and methods of use thereof
CN108276427A (zh) * 2018-01-14 2018-07-13 常州大学 一种安丝菌素p-3的提取与分离纯化方法
CN108330113B (zh) * 2018-03-08 2019-05-28 山东省医药生物技术研究中心（山东省病毒研究所） 一株高底物专一性酰基转移酶的珍贵束丝放线菌及其应用
CN113444106A (zh) * 2020-03-25 2021-09-28 重庆乾泰生物医药有限公司 一种高纯度安丝菌素的制备方法
CN112630368A (zh) * 2020-12-18 2021-04-09 卓和药业集团有限公司 安丝菌素含量的高效液相色谱检测分析方法
CN117597450A (zh) * 2021-06-18 2024-02-23 杭州中美华东制药有限公司 安丝菌素p-3的提纯方法
CN115477658A (zh) * 2022-10-12 2022-12-16 道中道（菏泽）制药有限公司 一种有效降低安丝菌素p-3杂质的结晶方法

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Also Published As

Publication number Publication date
US7432088B2 (en) 2008-10-07
NZ555437A (en) 2010-04-30
SI2514828T1 (sl) 2019-03-29
AU2005325166A1 (en) 2006-07-27
AU2005325166B2 (en) 2012-02-02
SG158905A1 (en) 2010-02-26
EA012524B1 (ru) 2009-10-30
WO2006078368A1 (en) 2006-07-27
CA2595024A1 (en) 2006-07-27
EP1838863A4 (en) 2011-10-05
CY1121372T1 (el) 2020-05-29
DK2514828T3 (en) 2019-03-11
BRPI0519624B1 (pt) 2021-01-19
KR101515873B1 (ko) 2015-04-29
JP5106120B2 (ja) 2012-12-26
PT2514828T (pt) 2019-02-15
CN104745655A (zh) 2015-07-01
CR9228A (es) 2008-03-31
ES2710875T3 (es) 2019-04-29
IL183918A (en) 2013-07-31
JP2008526267A (ja) 2008-07-24
EP2514828B1 (en) 2018-11-14
IL183918A0 (en) 2007-10-31
CA2834033A1 (en) 2006-07-27
IL215686A0 (en) 2011-11-30
TR201901647T4 (tr) 2019-02-21
IL215686A (en) 2013-07-31
NZ583446A (en) 2011-08-26
NO20074222L (no) 2007-10-18
LT2514828T (lt) 2019-02-25
BRPI0519624A2 (pt) 2009-02-25
CA2595024C (en) 2014-02-04
EP2514828A2 (en) 2012-10-24
KR20120099734A (ko) 2012-09-11
KR20070099576A (ko) 2007-10-09
CA2834033C (en) 2017-01-24
EP2514828A3 (en) 2013-07-03
US20050170475A1 (en) 2005-08-04
CN101103120A (zh) 2008-01-09
BRPI0519624B8 (pt) 2021-05-25
KR20130051019A (ko) 2013-05-16
HUE042312T2 (hu) 2019-06-28
EA200701310A1 (ru) 2008-06-30
NO342876B1 (no) 2018-08-20
MX2007008069A (es) 2007-08-21
PL2514828T3 (pl) 2019-04-30
EP1838863A1 (en) 2007-10-03
HK1211985A1 (en) 2016-06-03

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