CY1117030T1 - Τροποποιηση της εκφρασης απολιποπρωτεϊνης c-iii - Google Patents

Τροποποιηση της εκφρασης απολιποπρωτεϊνης c-iii

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Publication number
CY1117030T1
CY1117030T1 CY20151101109T CY151101109T CY1117030T1 CY 1117030 T1 CY1117030 T1 CY 1117030T1 CY 20151101109 T CY20151101109 T CY 20151101109T CY 151101109 T CY151101109 T CY 151101109T CY 1117030 T1 CY1117030 T1 CY 1117030T1
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Cyprus
Prior art keywords
iii
apolipoprotein
expression
modification
iii expression
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CY20151101109T
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English (en)
Inventor
Rosanne M Crooke
Mark J Graham
Kristina M Lemonidis-Tarbet
Kenneth Dobie
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Isis Pharmaceuticals, Inc.
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Publication date
Application filed by Isis Pharmaceuticals, Inc. filed Critical Isis Pharmaceuticals, Inc.
Publication of CY1117030T1 publication Critical patent/CY1117030T1/el

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

Δίδονται ενώσεις, συνθέσεις και μέθοδοι τροποποίησης της έκφρασης απολιποπρωτεΐνης C-III. Οι συνθέσεις περιέχουν ολιγονουκλεοτίδια τα οποία στοχεύουν προς το νουκλεϊκό οξύ το οποίο κωδικοποιεί την απολιποπρωτεΐνη C-III. Δίδονται μέθοδοι χρήσης των ενώσεων αυτών για την τροποποίηση της έκφρασης απολιποπρωτεΐνης C-III και για τη διάγνωση και θεραπευτική αγωγή νοσημάτων, τα οποία συσχετίζονται με την έκφραση της απολιποπρωτεΐνης C-III.
CY20151101109T 2003-04-16 2015-12-07 Τροποποιηση της εκφρασης απολιποπρωτεϊνης c-iii CY1117030T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/418,780 US7598227B2 (en) 2003-04-16 2003-04-16 Modulation of apolipoprotein C-III expression
EP11185507.8A EP2441449B1 (en) 2003-04-16 2004-04-15 Modulation of apolipoprotein C-III expression

Publications (1)

Publication Number Publication Date
CY1117030T1 true CY1117030T1 (el) 2017-04-05

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CY20151101109T CY1117030T1 (el) 2003-04-16 2015-12-07 Τροποποιηση της εκφρασης απολιποπρωτεϊνης c-iii

Country Status (14)

Country Link
US (6) US7598227B2 (el)
EP (4) EP1622597B1 (el)
AT (1) ATE529103T1 (el)
AU (2) AU2004231550B2 (el)
CA (2) CA2958943A1 (el)
CY (1) CY1117030T1 (el)
DK (2) DK1622597T3 (el)
ES (3) ES2666405T3 (el)
HK (1) HK1169609A1 (el)
HU (1) HUE027411T2 (el)
PL (1) PL2441449T3 (el)
PT (1) PT2441449E (el)
SI (1) SI2441449T1 (el)
WO (1) WO2004093783A2 (el)

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