CY1110706T1 - Αντιβακτηριδιακα παραγωγα κινολινης - Google Patents
Αντιβακτηριδιακα παραγωγα κινολινηςInfo
- Publication number
- CY1110706T1 CY1110706T1 CY20101100708T CY101100708T CY1110706T1 CY 1110706 T1 CY1110706 T1 CY 1110706T1 CY 20101100708 T CY20101100708 T CY 20101100708T CY 101100708 T CY101100708 T CY 101100708T CY 1110706 T1 CY1110706 T1 CY 1110706T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compounds
- preparation
- pharmaceutically acceptable
- treatment
- kinolin
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 125000000815 N-oxide group Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 abstract 1
- -1 compound ions Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125521 | 2006-12-06 | ||
| EP07847813A EP2086941B1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1110706T1 true CY1110706T1 (el) | 2015-06-10 |
Family
ID=37944337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100708T CY1110706T1 (el) | 2006-12-06 | 2010-07-28 | Αντιβακτηριδιακα παραγωγα κινολινης |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7998979B2 (https=) |
| EP (1) | EP2086941B1 (https=) |
| JP (1) | JP5356245B2 (https=) |
| KR (1) | KR101490221B1 (https=) |
| CN (1) | CN101541752B (https=) |
| AR (1) | AR064150A1 (https=) |
| AT (1) | ATE465994T1 (https=) |
| AU (1) | AU2007328889B2 (https=) |
| BR (1) | BRPI0720251B8 (https=) |
| CA (1) | CA2668520C (https=) |
| CL (1) | CL2007003516A1 (https=) |
| CY (1) | CY1110706T1 (https=) |
| DE (1) | DE602007006231D1 (https=) |
| DK (1) | DK2086941T3 (https=) |
| ES (1) | ES2344535T3 (https=) |
| HR (1) | HRP20100384T1 (https=) |
| IL (1) | IL199081A (https=) |
| JO (1) | JO2685B1 (https=) |
| ME (1) | ME01073B (https=) |
| MX (1) | MX2009005980A (https=) |
| NO (1) | NO341995B1 (https=) |
| NZ (1) | NZ576673A (https=) |
| PL (1) | PL2086941T3 (https=) |
| PT (1) | PT2086941E (https=) |
| RS (1) | RS51390B (https=) |
| RU (1) | RU2446159C2 (https=) |
| SI (1) | SI2086941T1 (https=) |
| TW (1) | TWI412364B (https=) |
| WO (1) | WO2008068269A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104254527B (zh) | 2012-04-27 | 2017-05-31 | 詹森药业有限公司 | 抗菌的喹啉衍生物 |
| ES2607879T3 (es) | 2012-04-27 | 2017-04-04 | Janssen Pharmaceutica N.V. | Derivados de quinolina antibacterianos |
| CN104650054B (zh) * | 2013-11-25 | 2019-09-13 | 重庆医药工业研究院有限责任公司 | 一种抗结核菌的喹啉噻吩芳氧乙胺衍生物 |
| US11857352B2 (en) | 2016-09-06 | 2024-01-02 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
| KR20240161147A (ko) | 2022-03-14 | 2024-11-12 | 슬랩 파마슈티컬스 엘엘씨 | 다중 사이클릭 화합물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6033389B2 (ja) * | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
| WO1998018326A1 (en) | 1996-10-28 | 1998-05-07 | Department Of The Army, U.S. Government | Compounds, compositions and methods for treating antibiotic-resistant infections |
| PT1412332E (pt) * | 2001-07-31 | 2005-06-30 | Jerome P Horwitz | Derivados de quinolina e sua utilizacao como agentes antitumorais |
| ATE463482T1 (de) * | 2002-07-25 | 2010-04-15 | Janssen Pharmaceutica Nv | Chinolinderivate und deren verwendung als mycobakterielle inhibitoren |
| EA011277B1 (ru) | 2004-01-23 | 2009-02-27 | Янссен Фармацевтика Н.В. | Производные хинолина и их применение в качестве ингибиторов микобактерий |
| EA011359B1 (ru) | 2004-01-23 | 2009-02-27 | Янссен Фармацевтика Н.В. | Замещенные хинолины и их применение в качестве микобактериальных ингибиторов |
| CA2554049C (en) * | 2004-01-29 | 2012-12-18 | Janssen Pharmaceutica N.V. | Quinoline derivatives for use as mycobacterial inhibitors |
| PL1753427T3 (pl) * | 2004-05-28 | 2008-09-30 | Janssen Pharmaceutica Nv | Zastosowanie podstawionych pochodnych chinoliny do leczenia chorób wywoływanych przez prątki lekooporne |
| PL1797115T3 (pl) | 2004-09-28 | 2017-12-29 | Janssen Pharmaceutica N.V. | Domena wiążąca bakteryjnej syntazy ATP |
-
2007
- 2007-11-29 JO JO2007507A patent/JO2685B1/en active
- 2007-12-04 DK DK07847813.8T patent/DK2086941T3/da active
- 2007-12-04 RU RU2009125525/04A patent/RU2446159C2/ru active
- 2007-12-04 HR HR20100384T patent/HRP20100384T1/hr unknown
- 2007-12-04 MX MX2009005980A patent/MX2009005980A/es active IP Right Grant
- 2007-12-04 AT AT07847813T patent/ATE465994T1/de active
- 2007-12-04 CN CN2007800437666A patent/CN101541752B/zh not_active Expired - Fee Related
- 2007-12-04 SI SI200730286T patent/SI2086941T1/sl unknown
- 2007-12-04 AU AU2007328889A patent/AU2007328889B2/en not_active Ceased
- 2007-12-04 JP JP2009539740A patent/JP5356245B2/ja not_active Expired - Fee Related
- 2007-12-04 RS RSP-2010/0340A patent/RS51390B/sr unknown
- 2007-12-04 BR BRPI0720251A patent/BRPI0720251B8/pt not_active IP Right Cessation
- 2007-12-04 KR KR1020097012572A patent/KR101490221B1/ko not_active Expired - Fee Related
- 2007-12-04 US US12/516,370 patent/US7998979B2/en active Active
- 2007-12-04 PT PT07847813T patent/PT2086941E/pt unknown
- 2007-12-04 PL PL07847813T patent/PL2086941T3/pl unknown
- 2007-12-04 WO PCT/EP2007/063315 patent/WO2008068269A1/en not_active Ceased
- 2007-12-04 CA CA2668520A patent/CA2668520C/en active Active
- 2007-12-04 DE DE602007006231T patent/DE602007006231D1/de active Active
- 2007-12-04 ES ES07847813T patent/ES2344535T3/es active Active
- 2007-12-04 ME MEP-2010-111A patent/ME01073B/me unknown
- 2007-12-04 NZ NZ576673A patent/NZ576673A/en not_active IP Right Cessation
- 2007-12-04 EP EP07847813A patent/EP2086941B1/en active Active
- 2007-12-05 AR ARP070105443A patent/AR064150A1/es unknown
- 2007-12-05 CL CL200703516A patent/CL2007003516A1/es unknown
- 2007-12-05 TW TW096146213A patent/TWI412364B/zh not_active IP Right Cessation
-
2009
- 2009-06-02 IL IL199081A patent/IL199081A/en active IP Right Grant
- 2009-07-06 NO NO20092540A patent/NO341995B1/no unknown
-
2010
- 2010-07-28 CY CY20101100708T patent/CY1110706T1/el unknown
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