CY1106637T1 - Υψηλης συγκεντρωσης σταθερα διαλυματα μελοξικαμης για ενεση ανευ βελονας - Google Patents

Υψηλης συγκεντρωσης σταθερα διαλυματα μελοξικαμης για ενεση ανευ βελονας

Info

Publication number
CY1106637T1
CY1106637T1 CY20071100735T CY071100735T CY1106637T1 CY 1106637 T1 CY1106637 T1 CY 1106637T1 CY 20071100735 T CY20071100735 T CY 20071100735T CY 071100735 T CY071100735 T CY 071100735T CY 1106637 T1 CY1106637 T1 CY 1106637T1
Authority
CY
Cyprus
Prior art keywords
meloxicam
needle
high concentration
free injection
stable solutions
Prior art date
Application number
CY20071100735T
Other languages
English (en)
Inventor
Stefan Henke
Martin Andreas Folger
Bernhard Hassel
Bernd Zierenberg
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of CY1106637T1 publication Critical patent/CY1106637T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Υδατικό διάλυμα μελοξικάμης χωρίς κυκλοδεξτρίνη για ένεση άνευ βελόνας, το οποίο περιέχει ένα φαρμακολογικά αποδεκτό άλας της μελοξικάμης μιας οργανικής ή ανόργανης βάσης και ένα ή περισσότερα κατάλληλα έκδοχα, όπου η περιεκτικότητα σε διαλυμένη μελοξικάμη κυμαίνεται από 35 έως 100 mg/ml. Το σύμφωνα με την εφεύρεση σκεύασμα έχει σταθερότητα στην αποθήκευση έως 24 μήνες ή περισσότερο.
CY20071100735T 2001-12-12 2007-06-04 Υψηλης συγκεντρωσης σταθερα διαλυματα μελοξικαμης για ενεση ανευ βελονας CY1106637T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10161077A DE10161077A1 (de) 2001-12-12 2001-12-12 Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
PCT/EP2002/013983 WO2003049733A1 (de) 2001-12-12 2002-12-10 Hochkonzentrierte stabile meloxicamlösungen zur nadellosen injektion

Publications (1)

Publication Number Publication Date
CY1106637T1 true CY1106637T1 (el) 2012-01-25

Family

ID=7708961

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100735T CY1106637T1 (el) 2001-12-12 2007-06-04 Υψηλης συγκεντρωσης σταθερα διαλυματα μελοξικαμης για ενεση ανευ βελονας

Country Status (17)

Country Link
US (5) US20030119825A1 (el)
EP (1) EP1455782B1 (el)
JP (1) JP5348818B2 (el)
AR (1) AR037789A1 (el)
AT (1) ATE357232T1 (el)
AU (1) AU2002361035A1 (el)
CA (1) CA2469588C (el)
CY (1) CY1106637T1 (el)
DE (2) DE10161077A1 (el)
DK (1) DK1455782T3 (el)
ES (1) ES2283634T3 (el)
PE (1) PE20030575A1 (el)
PT (1) PT1455782E (el)
SI (1) SI1455782T1 (el)
TW (1) TW200302720A (el)
UY (1) UY27575A1 (el)
WO (1) WO2003049733A1 (el)

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US20080132493A1 (en) 2008-06-05
WO2003049733A1 (de) 2003-06-19
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US20140066440A1 (en) 2014-03-06
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ATE357232T1 (de) 2007-04-15
US9993485B2 (en) 2018-06-12
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