CY1105410T1 - Υποκατεστημενες 2-φαινυλοβενζιμιδαζολες, η παρασκευη και η εφαρμογη τους - Google Patents

Υποκατεστημενες 2-φαινυλοβενζιμιδαζολες, η παρασκευη και η εφαρμογη τους

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Publication number
CY1105410T1
CY1105410T1 CY20051100286T CY051100286T CY1105410T1 CY 1105410 T1 CY1105410 T1 CY 1105410T1 CY 20051100286 T CY20051100286 T CY 20051100286T CY 051100286 T CY051100286 T CY 051100286T CY 1105410 T1 CY1105410 T1 CY 1105410T1
Authority
CY
Cyprus
Prior art keywords
phenylbenzimidazoles
preparation
application
substituted
well
Prior art date
Application number
CY20051100286T
Other languages
English (en)
Inventor
Wilfried Lubisch
Michael Kock
Thomas Hoger
Original Assignee
Abbott Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co. Kg filed Critical Abbott Gmbh & Co. Kg
Publication of CY1105410T1 publication Critical patent/CY1105410T1/el

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    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
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    • A61K31/4164—1,3-Diazoles
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    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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Abstract

Η παρούσα εφεύρεση αφορά νέες 2-φαινυλοβενζιμιδαζόλες του γενικού τύπου (I) ή (II), όπου οι ρίζες έχουν τις αναφερόμενες στην περιγραφή έννοιες, καθώς και οι ταυτομερείς μορφές τους, οι πιθανές εναντιομερείς ή διαστερεομερείς μορφές, τα προφάρμακά τους, καθώς και τα δυνατά φυσιολογικά υποφερτά άλατα, η παρασκευή και η εφαρμογή τους.
CY20051100286T 1998-11-03 2005-02-28 Υποκατεστημενες 2-φαινυλοβενζιμιδαζολες, η παρασκευη και η εφαρμογη τους CY1105410T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19850709 1998-11-03
DE19852801 1998-11-16
DE19908733 1999-03-01
PCT/EP1999/008169 WO2000026192A1 (de) 1998-11-03 1999-10-28 Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung

Publications (1)

Publication Number Publication Date
CY1105410T1 true CY1105410T1 (el) 2010-04-28

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CY20051100286T CY1105410T1 (el) 1998-11-03 2005-02-28 Υποκατεστημενες 2-φαινυλοβενζιμιδαζολες, η παρασκευη και η εφαρμογη τους

Country Status (26)

Country Link
US (1) US7781596B1 (el)
EP (2) EP1127052B1 (el)
JP (4) JP2002528531A (el)
KR (1) KR20010100977A (el)
CN (1) CN1331682A (el)
AR (1) AR024517A1 (el)
AT (1) ATE284392T1 (el)
AU (1) AU765224B2 (el)
BG (1) BG105515A (el)
BR (1) BR9915013A (el)
CA (1) CA2349227C (el)
CO (1) CO5140126A1 (el)
CY (1) CY1105410T1 (el)
CZ (1) CZ20011546A3 (el)
DE (1) DE59911249D1 (el)
ES (2) ES2449713T3 (el)
HK (1) HK1041702A1 (el)
HU (1) HUP0200312A3 (el)
ID (1) ID28787A (el)
IL (1) IL142917A0 (el)
NO (1) NO20012158L (el)
PL (1) PL347500A1 (el)
PT (1) PT1127052E (el)
SK (1) SK5952001A3 (el)
TR (2) TR200101239T2 (el)
WO (1) WO2000026192A1 (el)

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TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
AU2003275726A1 (en) * 2002-10-24 2004-05-13 Chong Kun Dang Pharmaceutical Corp. 2 - substituted heterocyclic compounds and antitumor composition comprising the same
US7151114B2 (en) 2003-01-09 2006-12-19 Boehringer Ingelheim International Gmbh Use of substituted 2-phenylbenzimidazoles as medicaments
DE10300398A1 (de) * 2003-01-09 2004-07-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von substituierten 2-Phenylbenzimidazolen als Arzneimittel
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