CU20130116A7 - Derivados de heteroarilo como moduladores de nachr alfa 7 - Google Patents

Derivados de heteroarilo como moduladores de nachr alfa 7

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Publication number
CU20130116A7
CU20130116A7 CU2013000116A CU20130116A CU20130116A7 CU 20130116 A7 CU20130116 A7 CU 20130116A7 CU 2013000116 A CU2013000116 A CU 2013000116A CU 20130116 A CU20130116 A CU 20130116A CU 20130116 A7 CU20130116 A7 CU 20130116A7
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CU
Cuba
Prior art keywords
analogs
heteroarilo
nachr
alfa
modulators
Prior art date
Application number
CU2013000116A
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English (en)
Other versions
CU24177B1 (es
Inventor
Neelima Sinha
Gourhari Jana
Sachchidanand Sachchidanand
Sanjay Pralhad Kurhade
Navnath Popat Karche
Anil Kashiram Hajare
Ajay Ramchandra Tilekar
Rajender Kumar Kamboj
Venkata P Palle
Original Assignee
Lupin Ltd
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45873193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20130116(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of CU20130116A7 publication Critical patent/CU20130116A7/es
Publication of CU24177B1 publication Critical patent/CU24177B1/es

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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Abstract

Se divulga un compuesto de la fórmula (I), en donde Z, m y R1 -R6 se describen en la misma, como un modulador de receptores de acetilcolina nicotínica particularmente del subtipo alfa 7, en un sujeto en necesidad del mismo, así como sus análogos, profármacos, análogos isotópicamente sustituidos, metabólicos, sales farmacéuticamente aceptables, polimorfos, solvatos, isómeros, clatratos y co- cristales, para su uso ya sea solos o en combinaciones con otros medicamentos adecuados, y composiciones farmacéuticas que contienen dichos compuestos y análogos. También se divulgan un proceso de preparación de los compuestos y sus usos pretendidos en terapia, particularmente en la profilaxis y terapia de trastornos tales como la enfermedad de Alzheimer, deterioro cognitivo leve, demencia senil, y similares.
CUP2013000116A 2011-02-23 2012-02-22 Derivados de heteroarilo como moduladores de nachr alfa 7 CU24177B1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN242KO2011 2011-02-23
IN1184KO2011 2011-09-09
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