TN2013000345A1 - Heteroaryl derivatives as alpha7 nachr modulators - Google Patents
Heteroaryl derivatives as alpha7 nachr modulatorsInfo
- Publication number
- TN2013000345A1 TN2013000345A1 TNP2013000345A TN2013000345A TN2013000345A1 TN 2013000345 A1 TN2013000345 A1 TN 2013000345A1 TN P2013000345 A TNP2013000345 A TN P2013000345A TN 2013000345 A TN2013000345 A TN 2013000345A TN 2013000345 A1 TN2013000345 A1 TN 2013000345A1
- Authority
- TN
- Tunisia
- Prior art keywords
- analogues
- therapy
- compounds
- disclosed
- heteroaryl derivatives
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Disclosed is a compound of formula (I), wherein Z, m and R1 -R6 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the α7 subtype, in a subject in need thereof, as well as analogues, prodrugs, isotopically substituted analogs, metabolites, pharmaceutically acceptable salts, polymorphs, solvates, isomers, clathrates, and co-crystal thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds and analogues. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN242KO2011 | 2011-02-23 | ||
PCT/IB2012/050806 WO2012114285A1 (en) | 2011-02-23 | 2012-02-22 | Heteroaryl derivatives as alpha7 nachr modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2013000345A1 true TN2013000345A1 (en) | 2015-01-20 |
Family
ID=52394780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2013000345A TN2013000345A1 (en) | 2011-02-23 | 2013-08-15 | Heteroaryl derivatives as alpha7 nachr modulators |
Country Status (2)
Country | Link |
---|---|
TN (1) | TN2013000345A1 (en) |
UA (1) | UA112076C2 (en) |
-
2012
- 2012-02-22 UA UAA201311194A patent/UA112076C2/en unknown
-
2013
- 2013-08-15 TN TNP2013000345A patent/TN2013000345A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
UA112076C2 (en) | 2016-07-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX343788B (en) | Heteroaryl derivatives as alpha7 nachr modulators. | |
MX344696B (en) | Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as alzheimer's and parkinson's disease. | |
IN2014MN01756A (en) | ||
MX2020010151A (en) | 1,4-disubstituted pyridazine analogs and methods for treating smn-deficiency-related conditions. | |
SI2875011T1 (en) | 5-ht3 receptor antagonists | |
MD20140037A2 (en) | (4-Phenylimidazol-2-yl)ethylamine derivatives useful as sodium channel modulators | |
IN2014CN00989A (en) | ||
EA201490807A1 (en) | NEW SUBSTITUTED IMIDAZOPIRIMIDINES AS GPBAR1 MODULATORS | |
WO2012122340A8 (en) | Soluble guanylate cyclase activators | |
HK1149258A1 (en) | Compounds | |
GEP20166483B (en) | Phenyl-3-aza-bicyclo[3.1.0] hex-3-yl-methanones and the use thereof as medicament | |
PT2323972E (en) | C7-fluoro substituted tetracycline compounds | |
WO2011123536A8 (en) | Polycyclic tetracycline compounds | |
WO2011025982A3 (en) | Tetracycline compounds | |
MY183111A (en) | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators | |
WO2009140341A3 (en) | Atorvastatin compositions | |
WO2013177534A3 (en) | New salicylic acid derivatives, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof | |
MX364400B (en) | Tetracycline compounds. | |
JP2015502371A5 (en) | ||
WO2010132670A3 (en) | Pentacycline compounds | |
MX2010012189A (en) | Quinuclidine derivatives as muscarinic m3 receptor antagonists. | |
WO2014014794A3 (en) | Mineralocorticoid receptor antagonists | |
NZ601284A (en) | Sulfone compounds as 5-ht6 receptor ligands | |
NZ600536A (en) | Bicyclic compounds as alpha4 beta2 nicotinic acetylcholine receptor ligands | |
TN2013000345A1 (en) | Heteroaryl derivatives as alpha7 nachr modulators |