TN2013000345A1 - Heteroaryl derivatives as alpha7 nachr modulators - Google Patents

Heteroaryl derivatives as alpha7 nachr modulators

Info

Publication number
TN2013000345A1
TN2013000345A1 TNP2013000345A TN2013000345A TN2013000345A1 TN 2013000345 A1 TN2013000345 A1 TN 2013000345A1 TN P2013000345 A TNP2013000345 A TN P2013000345A TN 2013000345 A TN2013000345 A TN 2013000345A TN 2013000345 A1 TN2013000345 A1 TN 2013000345A1
Authority
TN
Tunisia
Prior art keywords
analogues
therapy
compounds
disclosed
heteroaryl derivatives
Prior art date
Application number
TNP2013000345A
Other languages
French (fr)
Inventor
Neelima Sinha
Gourhari Jana
Sachchidanand Sachchidanand
Sanjay Pralhad Kurhade
Navnath Popat Karche
Anil Kashiram Hajare
Ajay Ramchandra Tilekar
Venkata P Palle
Rajender Kumar Kamboj
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2012/050806 external-priority patent/WO2012114285A1/en
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of TN2013000345A1 publication Critical patent/TN2013000345A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed is a compound of formula (I), wherein Z, m and R1 -R6 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the α7 subtype, in a subject in need thereof, as well as analogues, prodrugs, isotopically substituted analogs, metabolites, pharmaceutically acceptable salts, polymorphs, solvates, isomers, clathrates, and co-crystal thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds and analogues. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
TNP2013000345A 2011-02-23 2013-08-15 Heteroaryl derivatives as alpha7 nachr modulators TN2013000345A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN242KO2011 2011-02-23
PCT/IB2012/050806 WO2012114285A1 (en) 2011-02-23 2012-02-22 Heteroaryl derivatives as alpha7 nachr modulators

Publications (1)

Publication Number Publication Date
TN2013000345A1 true TN2013000345A1 (en) 2015-01-20

Family

ID=52394780

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2013000345A TN2013000345A1 (en) 2011-02-23 2013-08-15 Heteroaryl derivatives as alpha7 nachr modulators

Country Status (2)

Country Link
TN (1) TN2013000345A1 (en)
UA (1) UA112076C2 (en)

Also Published As

Publication number Publication date
UA112076C2 (en) 2016-07-25

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