CS270420B2 - Method of mucopolysaccharides production with increased antitrombotic activity - Google Patents

Method of mucopolysaccharides production with increased antitrombotic activity Download PDF

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Publication number
CS270420B2
CS270420B2 CS857467A CS746785A CS270420B2 CS 270420 B2 CS270420 B2 CS 270420B2 CS 857467 A CS857467 A CS 857467A CS 746785 A CS746785 A CS 746785A CS 270420 B2 CS270420 B2 CS 270420B2
Authority
CS
Czechoslovakia
Prior art keywords
mixture
chains
usp
titer
mucopolysaccharide
Prior art date
Application number
CS857467A
Other languages
Czech (cs)
English (en)
Other versions
CS746785A2 (en
Inventor
Jean-Claude Ing Lormeau
Jean Choay
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay Sa filed Critical Choay Sa
Publication of CS746785A2 publication Critical patent/CS746785A2/cs
Publication of CS270420B2 publication Critical patent/CS270420B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
CS857467A 1984-10-18 1985-10-18 Method of mucopolysaccharides production with increased antitrombotic activity CS270420B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8415978A FR2572080B1 (fr) 1984-10-18 1984-10-18 Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments

Publications (2)

Publication Number Publication Date
CS746785A2 CS746785A2 (en) 1989-11-14
CS270420B2 true CS270420B2 (en) 1990-06-13

Family

ID=9308784

Family Applications (1)

Application Number Title Priority Date Filing Date
CS857467A CS270420B2 (en) 1984-10-18 1985-10-18 Method of mucopolysaccharides production with increased antitrombotic activity

Country Status (18)

Country Link
JP (1) JPS61101502A (es)
KR (1) KR920006002B1 (es)
AR (1) AR243539A1 (es)
CS (1) CS270420B2 (es)
DD (1) DD239798A5 (es)
DZ (1) DZ844A1 (es)
EG (1) EG17478A (es)
FI (1) FI81810C (es)
FR (1) FR2572080B1 (es)
HU (1) HU197931B (es)
IL (1) IL76701A (es)
MA (1) MA20554A1 (es)
NO (1) NO166369C (es)
PL (1) PL146770B1 (es)
SU (1) SU1570651A3 (es)
UA (1) UA5929A1 (es)
YU (1) YU45285B (es)
ZA (1) ZA857902B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64121B1 (en) * 1989-10-04 1995-07-12 Akzo Nv Sulphated glycosaminoglycuronan with antithrombotic activity
CN103209997B (zh) * 2010-09-14 2016-03-16 国立大学法人宫崎大学 高纯度肝素及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478646A2 (fr) * 1980-03-20 1981-09-25 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
FR2440376A1 (fr) * 1978-11-06 1980-05-30 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
FR2495935A1 (fr) * 1980-12-15 1982-06-18 Choay Sa Fractions mucopolysaccharidiques possedant des proprietes biologiques, leur procede de preparation et leur application en tant que medicaments
FR2503714B1 (fr) * 1981-04-10 1986-11-21 Choay Sa Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine

Also Published As

Publication number Publication date
UA5929A1 (uk) 1994-12-29
EG17478A (en) 1991-03-30
NO166369B (no) 1991-04-02
FI854073A0 (fi) 1985-10-18
YU45285B (en) 1992-05-28
FR2572080A1 (fr) 1986-04-25
PL255832A1 (en) 1987-02-09
YU166085A (en) 1988-06-30
DZ844A1 (fr) 2004-09-13
NO166369C (no) 1991-07-17
CS746785A2 (en) 1989-11-14
DD239798A5 (de) 1986-10-08
ZA857902B (en) 1987-03-25
HU197931B (en) 1989-06-28
FI854073L (fi) 1986-04-19
JPH0552841B2 (es) 1993-08-06
KR860003275A (ko) 1986-05-21
MA20554A1 (fr) 1986-07-01
IL76701A (en) 1990-09-17
AR243539A1 (es) 1993-08-31
HUT38657A (en) 1986-06-30
FR2572080B1 (fr) 1987-06-26
JPS61101502A (ja) 1986-05-20
FI81810B (fi) 1990-08-31
PL146770B1 (en) 1989-03-31
NO854154L (no) 1986-04-21
IL76701A0 (en) 1986-02-28
KR920006002B1 (ko) 1992-07-25
FI81810C (fi) 1990-12-10
SU1570651A3 (ru) 1990-06-07

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20001018