FI81810C - Foerfarande foer framstaellning av mukopolysackarider med hoeg antitrombotisk aktivitet. - Google Patents

Foerfarande foer framstaellning av mukopolysackarider med hoeg antitrombotisk aktivitet. Download PDF

Info

Publication number
FI81810C
FI81810C FI854073A FI854073A FI81810C FI 81810 C FI81810 C FI 81810C FI 854073 A FI854073 A FI 854073A FI 854073 A FI854073 A FI 854073A FI 81810 C FI81810 C FI 81810C
Authority
FI
Finland
Prior art keywords
mps
usp
process according
compositions
titers
Prior art date
Application number
FI854073A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI81810B (fi
FI854073L (fi
FI854073A0 (fi
Inventor
Jean-Claude Lormeau
Jean Choay
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay Sa filed Critical Choay Sa
Publication of FI854073A0 publication Critical patent/FI854073A0/fi
Publication of FI854073L publication Critical patent/FI854073L/fi
Publication of FI81810B publication Critical patent/FI81810B/fi
Application granted granted Critical
Publication of FI81810C publication Critical patent/FI81810C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
FI854073A 1984-10-18 1985-10-18 Foerfarande foer framstaellning av mukopolysackarider med hoeg antitrombotisk aktivitet. FI81810C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8415978A FR2572080B1 (fr) 1984-10-18 1984-10-18 Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments
FR8415978 1984-10-18

Publications (4)

Publication Number Publication Date
FI854073A0 FI854073A0 (fi) 1985-10-18
FI854073L FI854073L (fi) 1986-04-19
FI81810B FI81810B (fi) 1990-08-31
FI81810C true FI81810C (fi) 1990-12-10

Family

ID=9308784

Family Applications (1)

Application Number Title Priority Date Filing Date
FI854073A FI81810C (fi) 1984-10-18 1985-10-18 Foerfarande foer framstaellning av mukopolysackarider med hoeg antitrombotisk aktivitet.

Country Status (18)

Country Link
JP (1) JPS61101502A (es)
KR (1) KR920006002B1 (es)
AR (1) AR243539A1 (es)
CS (1) CS270420B2 (es)
DD (1) DD239798A5 (es)
DZ (1) DZ844A1 (es)
EG (1) EG17478A (es)
FI (1) FI81810C (es)
FR (1) FR2572080B1 (es)
HU (1) HU197931B (es)
IL (1) IL76701A (es)
MA (1) MA20554A1 (es)
NO (1) NO166369C (es)
PL (1) PL146770B1 (es)
SU (1) SU1570651A3 (es)
UA (1) UA5929A1 (es)
YU (1) YU45285B (es)
ZA (1) ZA857902B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0421508B1 (en) * 1989-10-04 1993-12-15 Akzo Nobel N.V. Sulphated glycosaminoglycuronan with antithrombotic activity
WO2012036152A1 (ja) * 2010-09-14 2012-03-22 国立大学法人 宮崎大学 高純度ヘパリンおよびその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478646A2 (fr) * 1980-03-20 1981-09-25 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
FR2440376A1 (fr) * 1978-11-06 1980-05-30 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
FR2495935A1 (fr) * 1980-12-15 1982-06-18 Choay Sa Fractions mucopolysaccharidiques possedant des proprietes biologiques, leur procede de preparation et leur application en tant que medicaments
FR2503714B1 (fr) * 1981-04-10 1986-11-21 Choay Sa Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine

Also Published As

Publication number Publication date
FI81810B (fi) 1990-08-31
HU197931B (en) 1989-06-28
JPH0552841B2 (es) 1993-08-06
JPS61101502A (ja) 1986-05-20
CS746785A2 (en) 1989-11-14
EG17478A (en) 1991-03-30
KR860003275A (ko) 1986-05-21
IL76701A (en) 1990-09-17
NO166369C (no) 1991-07-17
FI854073L (fi) 1986-04-19
FI854073A0 (fi) 1985-10-18
DZ844A1 (fr) 2004-09-13
CS270420B2 (en) 1990-06-13
MA20554A1 (fr) 1986-07-01
PL255832A1 (en) 1987-02-09
SU1570651A3 (ru) 1990-06-07
IL76701A0 (en) 1986-02-28
UA5929A1 (uk) 1994-12-29
NO166369B (no) 1991-04-02
DD239798A5 (de) 1986-10-08
ZA857902B (en) 1987-03-25
YU166085A (en) 1988-06-30
NO854154L (no) 1986-04-21
YU45285B (en) 1992-05-28
FR2572080A1 (fr) 1986-04-25
HUT38657A (en) 1986-06-30
KR920006002B1 (ko) 1992-07-25
PL146770B1 (en) 1989-03-31
AR243539A1 (es) 1993-08-31
FR2572080B1 (fr) 1987-06-26

Similar Documents

Publication Publication Date Title
RU2099350C1 (ru) Ассоциаты депротонированной гиалуроновой кислоты, способ их получения, фармацевтическая композиция, содержащая ассоциаты депротонированной гиалуроновой кислоты, и способ ее получения
CA1327968C (fr) Heparines de bas poids moleculaire, a structure reguliere leur preparation et leurs applications biologiques
US4686288A (en) Process for preparing mucopolysaccharide compositions having high antithrombotic activity, the compositions obtained and their use as medicaments
Yamada et al. Preparation and anti-HIV activity of low-molecular-weight carrageenans and their sulfated derivatives
JP5816342B2 (ja) 非抗凝固性多糖組成物
Wasty et al. Distribution of glycosaminoglycans in the intima of human aortas: changes in atherosclerosis and diabetes mellitus
DK173818B1 (da) Heparinderivat
ES2817779T3 (es) Evaluación de preparaciones de heparina
US4533549A (en) Antithrombotic agent
EP0040144A1 (fr) Nouveaux polysaccharides sulfatés, procédés pour leur préparation et leur utilisation comme médicaments
DE68916878T2 (de) Selektiv O-acylierte Glycosaminoglykane.
US4788307A (en) Oligosaccharidic fractions devoid or practically devoid of antithrombotic activity
EP1752772B1 (de) Faktor Xa basiertes Heparin-Testverfahren unter Verwendung einer Heparin-modifizierenden Komponente
AU608512B2 (en) Sulfated polysaccharide
McAllister et al. Heparin metabolism: isolation and characterization of uroheparin
FI81810C (fi) Foerfarande foer framstaellning av mukopolysackarider med hoeg antitrombotisk aktivitet.
IT9021909A1 (it) Procedimento per la preparazione di epossi-eparidi prodotti ottenuti e composizioni farmaceutiche che li contengono
Gandy et al. Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate
JP2010518251A (ja) ビオチンまたはビオチン誘導体との少なくとも1つの共有結合を含むヘパリン、これらの調製方法およびこれらの使用
Prokopek The tilorone-induced mucopolysaccharidosis in rats: Biochemical investigations
Cziner et al. Vacuum ultraviolet circular dichroism of dermatan sulfate: Iduronate ring geometry in solution and solid state
Toby et al. Detection of native chondroitin sulfate impurities in heparin sodium with a colorimetric micro-plate based assay
CN1554671A (zh) 一种低亚硝酸盐含量的低分子肝素钙的制备方法
Bonavita et al. The urinary excretion of heparan sulfate by juvenile-and adult-onset diabetic patients
US5472950A (en) Compositions containing cobalt hyaluronic acid complex

Legal Events

Date Code Title Description
FG Patent granted

Owner name: SANOFI-SYNTHELABO

PC Transfer of assignment of patent

Owner name: SANOFI-AVENTIS

MA Patent expired