CS265250B2 - Process for preparing anhydrous crystalline natrium salt of 5-chlor-3-/2-thenoyl/-2-oxindol-1-carboxamide - Google Patents

Process for preparing anhydrous crystalline natrium salt of 5-chlor-3-/2-thenoyl/-2-oxindol-1-carboxamide Download PDF

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Publication number
CS265250B2
CS265250B2 CS88648A CS64888A CS265250B2 CS 265250 B2 CS265250 B2 CS 265250B2 CS 88648 A CS88648 A CS 88648A CS 64888 A CS64888 A CS 64888A CS 265250 B2 CS265250 B2 CS 265250B2
Authority
CS
Czechoslovakia
Prior art keywords
thenoyl
carboxamide
salt
oxindol
chlor
Prior art date
Application number
CS88648A
Other languages
Czech (cs)
English (en)
Other versions
CS64888A2 (en
Inventor
Douglas John Meldrum Allen
Brian Thomas Ooneill
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS64888A2 publication Critical patent/CS64888A2/cs
Publication of CS265250B2 publication Critical patent/CS265250B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS88648A 1987-02-02 1988-02-02 Process for preparing anhydrous crystalline natrium salt of 5-chlor-3-/2-thenoyl/-2-oxindol-1-carboxamide CS265250B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/000201 WO1988005656A1 (en) 1987-02-02 1987-02-02 Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Publications (2)

Publication Number Publication Date
CS64888A2 CS64888A2 (en) 1988-08-16
CS265250B2 true CS265250B2 (en) 1989-10-13

Family

ID=22202263

Family Applications (2)

Application Number Title Priority Date Filing Date
CS88648A CS265250B2 (en) 1987-02-02 1988-02-02 Process for preparing anhydrous crystalline natrium salt of 5-chlor-3-/2-thenoyl/-2-oxindol-1-carboxamide
CS913541A CS354191A3 (en) 1987-02-02 1991-11-22 Anhydrous crystalline sodium salt of 5-chloro-3-/2-thenoyl/-2-oxindole-1-carboxamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS913541A CS354191A3 (en) 1987-02-02 1991-11-22 Anhydrous crystalline sodium salt of 5-chloro-3-/2-thenoyl/-2-oxindole-1-carboxamide

Country Status (42)

Country Link
US (1) US5036099A (de)
EP (1) EP0277738B1 (de)
JP (1) JPS63201184A (de)
KR (1) KR900001422B1 (de)
CN (1) CN1022324C (de)
AP (1) AP52A (de)
AR (1) AR243182A1 (de)
AT (1) ATE73800T1 (de)
AU (1) AU587736B2 (de)
BG (1) BG51042A3 (de)
CA (1) CA1335590C (de)
CS (2) CS265250B2 (de)
CY (1) CY1775A (de)
DD (1) DD267490A5 (de)
DE (1) DE3869149D1 (de)
DK (1) DK44888A (de)
EC (1) ECSP941082A (de)
ES (1) ES2032955T3 (de)
FI (1) FI89598C (de)
GR (1) GR3004200T3 (de)
HK (1) HK132695A (de)
IE (1) IE60000B1 (de)
IL (1) IL85277A (de)
IN (1) IN171799B (de)
IS (1) IS1533B (de)
LV (1) LV10252B (de)
MA (1) MA21171A1 (de)
MY (1) MY102737A (de)
NO (1) NO170581C (de)
NZ (1) NZ223373A (de)
OA (1) OA08710A (de)
PH (1) PH26545A (de)
PL (1) PL149550B1 (de)
PT (1) PT86675B (de)
RO (1) RO105052B1 (de)
RU (1) RU2011381C1 (de)
SG (1) SG27994G (de)
SI (1) SI8810183A8 (de)
UA (1) UA25898A1 (de)
WO (1) WO1988005656A1 (de)
YU (1) YU46766B (de)
ZA (1) ZA88679B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
DE68923673T2 (de) * 1988-10-18 1996-01-18 Pfizer Prodrogen von antiinflammatorischen 3-Acyl-2-oxindol-1-carboxamiden.
SK278175B6 (en) * 1988-10-18 1996-03-06 Pfizer 3-acyl-2-oxindole-1-carboxamides and method of their preparation
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
US5006547A (en) * 1990-03-19 1991-04-09 Pfizer Inc. Tenidap as an inhibitor of the release of elastase by neutrophils
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
WO1997022605A1 (en) * 1995-12-19 1997-06-26 Pfizer Inc. Stable, long acting salts of indole derivatives for the treatment of joint diseases
EP0826685A1 (de) * 1996-08-21 1998-03-04 Pfizer Inc. Stabile, lange aktive Salze von Carboxamiden für die Behandlung von Gelenkskrankheiten
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
US7407195B2 (en) * 2004-04-14 2008-08-05 William Berson Label for receiving indicia having variable spectral emissivity values
US7651031B2 (en) 2004-10-25 2010-01-26 William Berson Systems and methods for reading indicium
US7621451B2 (en) * 2005-01-14 2009-11-24 William Berson Radio frequency identification labels and systems and methods for making the same
US7931413B2 (en) * 2005-01-14 2011-04-26 William Berson Printing system ribbon including print transferable circuitry and elements
US7728726B2 (en) * 2005-01-14 2010-06-01 William Berson Radio frequency identification labels
US7619520B2 (en) * 2005-01-14 2009-11-17 William Berson Radio frequency identification labels and systems and methods for making the same
BR112020008852A2 (pt) 2017-11-02 2020-10-20 Accurate Medical Therapeutics Ltd. cateter para embolização com filtro integrado

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767653A (en) * 1971-06-28 1973-10-23 Squibb & Sons Inc Thiazines
GB1532413A (en) * 1974-12-23 1978-11-15 Union International Co Ltd Chenodeoxycholic acid
DE2613346C3 (de) * 1976-03-29 1981-07-23 Diamalt AG, 8000 München Monoklin kristalline Chenodesoxycholsäure und Verfahren zu ihrer Herstellung
ATE63543T1 (de) * 1984-02-07 1991-06-15 Pfizer 2-oxindolzwischenprodukte.
PT80116B (pt) * 1984-03-19 1987-10-20 Pfizer Processo para a producao de 2-oxindole-1-carboxamidas e de intermediarios para esse efeito
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents

Also Published As

Publication number Publication date
KR900001422B1 (ko) 1990-03-09
IN171799B (de) 1993-01-09
RU2011381C1 (ru) 1994-04-30
DK44888A (da) 1988-08-03
JPH0576945B2 (de) 1993-10-25
DD267490A5 (de) 1989-05-03
JPS63201184A (ja) 1988-08-19
LV10252B (en) 1995-04-20
HK132695A (en) 1995-09-01
ATE73800T1 (de) 1992-04-15
FI89598B (fi) 1993-07-15
CY1775A (en) 1996-04-05
NZ223373A (en) 1989-06-28
MA21171A1 (fr) 1988-10-01
US5036099A (en) 1991-07-30
EP0277738B1 (de) 1992-03-18
IS3309A7 (is) 1988-08-03
FI893647A0 (fi) 1989-08-01
IE880269L (en) 1988-08-02
PH26545A (en) 1992-08-19
CA1335590C (en) 1995-05-16
DK44888D0 (da) 1988-01-29
WO1988005656A1 (en) 1988-08-11
NO884329D0 (no) 1988-09-29
SI8810183A8 (sl) 1996-08-31
ECSP941082A (es) 1994-12-15
MY102737A (en) 1992-09-30
ES2032955T3 (es) 1996-07-16
AR243182A1 (es) 1993-07-30
PL270415A1 (en) 1988-12-08
NO170581C (no) 1992-11-04
UA25898A1 (uk) 1999-02-26
NO170581B (no) 1992-07-27
PL149550B1 (en) 1990-02-28
CS354191A3 (en) 1992-04-15
PT86675B (pt) 1992-07-31
AU587736B2 (en) 1989-08-24
OA08710A (fr) 1989-03-31
YU46766B (sh) 1994-05-10
NO884329L (no) 1988-09-29
DE3869149D1 (de) 1992-04-23
IL85277A0 (en) 1988-07-31
EP0277738A1 (de) 1988-08-10
CN1022324C (zh) 1993-10-06
IS1533B (is) 1994-01-28
AP52A (en) 1989-09-16
IE60000B1 (en) 1994-05-18
KR880009961A (ko) 1988-10-06
AP8800081A0 (en) 1987-11-01
CN88100555A (zh) 1988-08-17
CS64888A2 (en) 1988-08-16
ZA88679B (en) 1989-09-27
PT86675A (pt) 1988-03-01
LV10252A (lv) 1994-10-20
SG27994G (en) 1994-10-14
GR3004200T3 (de) 1993-03-31
BG51042A3 (en) 1993-01-15
IL85277A (en) 1994-02-27
YU18388A (en) 1989-10-31
AU1116088A (en) 1988-08-04
FI89598C (fi) 1993-10-25
RO105052B1 (en) 1994-12-01

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