CS235503B2 - Method of vindesinmonosulphate preparation - Google Patents

Method of vindesinmonosulphate preparation Download PDF

Info

Publication number
CS235503B2
CS235503B2 CS796720A CS672079A CS235503B2 CS 235503 B2 CS235503 B2 CS 235503B2 CS 796720 A CS796720 A CS 796720A CS 672079 A CS672079 A CS 672079A CS 235503 B2 CS235503 B2 CS 235503B2
Authority
CS
Czechoslovakia
Prior art keywords
sulfuric acid
vindesine
rate
added
addition
Prior art date
Application number
CS796720A
Other languages
Czech (cs)
English (en)
Inventor
Stanislav Rolski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS235503B2 publication Critical patent/CS235503B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
CS796720A 1978-10-10 1979-10-03 Method of vindesinmonosulphate preparation CS235503B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94959578A 1978-10-10 1978-10-10

Publications (1)

Publication Number Publication Date
CS235503B2 true CS235503B2 (en) 1985-05-15

Family

ID=25489302

Family Applications (1)

Application Number Title Priority Date Filing Date
CS796720A CS235503B2 (en) 1978-10-10 1979-10-03 Method of vindesinmonosulphate preparation

Country Status (32)

Country Link
EP (1) EP0009996B1 (xx)
JP (1) JPS5553295A (xx)
KR (1) KR850000150B1 (xx)
AR (1) AR225153A1 (xx)
AT (1) AT370422B (xx)
AU (1) AU525702B2 (xx)
BE (1) BE879213A (xx)
BG (1) BG34763A3 (xx)
CA (1) CA1114817A (xx)
CH (2) CH645120A5 (xx)
CS (1) CS235503B2 (xx)
DD (1) DD146461A5 (xx)
DE (1) DE2964913D1 (xx)
DK (1) DK146823C (xx)
EG (1) EG14140A (xx)
ES (1) ES484827A1 (xx)
FI (1) FI70223C (xx)
FR (1) FR2438659A1 (xx)
GB (1) GB2031893B (xx)
GR (1) GR72394B (xx)
HU (1) HU180744B (xx)
IE (1) IE48958B1 (xx)
IL (1) IL58390A (xx)
LU (1) LU81763A1 (xx)
MY (1) MY8500569A (xx)
NZ (1) NZ191744A (xx)
PH (1) PH16092A (xx)
PL (1) PL117678B1 (xx)
PT (1) PT70269A (xx)
RO (1) RO77380A (xx)
YU (1) YU241179A (xx)
ZA (1) ZA795268B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) * 2020-12-22 2022-03-22 海南长春花药业有限公司 一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
GR69783B (xx) * 1976-09-08 1982-07-07 Lilly Co Eli

Also Published As

Publication number Publication date
DD146461A5 (de) 1981-02-11
EG14140A (en) 1983-09-30
MY8500569A (en) 1985-12-31
AU5142779A (en) 1980-04-17
LU81763A1 (fr) 1980-01-24
CA1114817A (en) 1981-12-22
BE879213A (fr) 1980-04-08
HU180744B (en) 1983-04-29
DK422979A (da) 1980-04-11
FI793065A (fi) 1980-04-11
JPS628119B2 (xx) 1987-02-20
EP0009996A1 (en) 1980-04-16
AU525702B2 (en) 1982-11-25
RO77380A (ro) 1981-11-04
ES484827A1 (es) 1980-10-01
ATA658279A (de) 1982-08-15
AT370422B (de) 1983-03-25
FR2438659B1 (xx) 1983-03-18
JPS5553295A (en) 1980-04-18
IL58390A0 (en) 1980-01-31
KR850000150B1 (ko) 1985-02-28
FR2438659A1 (fr) 1980-05-09
FI70223C (fi) 1986-09-15
DK146823C (da) 1984-07-02
FI70223B (fi) 1986-02-28
AR225153A1 (es) 1982-02-26
DK146823B (da) 1984-01-16
IE48958B1 (en) 1985-06-26
ZA795268B (en) 1981-05-27
GR72394B (xx) 1983-11-01
EP0009996B1 (en) 1983-02-23
BG34763A3 (en) 1983-11-15
PH16092A (en) 1983-06-20
GB2031893A (en) 1980-04-30
YU241179A (en) 1983-01-21
IL58390A (en) 1982-07-30
IE791914L (en) 1980-04-10
GB2031893B (en) 1983-03-30
KR830001282A (ko) 1983-04-30
NZ191744A (en) 1981-05-29
PL117678B1 (en) 1981-08-31
CH649301A5 (fr) 1985-05-15
PL218756A1 (xx) 1980-06-16
CH645120A5 (fr) 1984-09-14
DE2964913D1 (en) 1983-03-31
PT70269A (de) 1979-11-01

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