CS231214B1 - Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea - Google Patents

Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea Download PDF

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Publication number
CS231214B1
CS231214B1 CS821734A CS173482A CS231214B1 CS 231214 B1 CS231214 B1 CS 231214B1 CS 821734 A CS821734 A CS 821734A CS 173482 A CS173482 A CS 173482A CS 231214 B1 CS231214 B1 CS 231214B1
Authority
CS
Czechoslovakia
Prior art keywords
alpha
formula
ergolinyl
group
substituted
Prior art date
Application number
CS821734A
Other languages
Czech (cs)
English (en)
Inventor
Antonin Cerny
Jiri Krepelka
Miroslav Seda
Karel Rezabek
Original Assignee
Antonin Cerny
Jiri Krepelka
Miroslav Seda
Karel Rezabek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antonin Cerny, Jiri Krepelka, Miroslav Seda, Karel Rezabek filed Critical Antonin Cerny
Priority to CS821734A priority Critical patent/CS231214B1/cs
Priority to DK84683A priority patent/DK84683A/da
Priority to AT0072783A priority patent/AT383349B/de
Priority to GB08305735A priority patent/GB2116548B/en
Priority to NL8300829A priority patent/NL8300829A/nl
Priority to IT19935/83A priority patent/IT1161209B/it
Priority to FI830754A priority patent/FI830754L/fi
Priority to SE8301257A priority patent/SE452321B/sv
Priority to AU12167/83A priority patent/AU555961B2/en
Priority to CA000423264A priority patent/CA1203531A/en
Priority to BE0/210287A priority patent/BE896122A/fr
Priority to CH1351/83A priority patent/CH652125A5/de
Priority to DE3308719A priority patent/DE3308719A1/de
Priority to FR8304005A priority patent/FR2523131B1/fr
Priority to JP58039349A priority patent/JPS58180484A/ja
Publication of CS231214B1 publication Critical patent/CS231214B1/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS821734A 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea CS231214B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea
DK84683A DK84683A (da) 1982-03-12 1983-02-24 1-substituerede n-(8alfa-ergolinyl)-n',n'-dimethylurinstoffer og fremgangsmaader til fremstilling deraf
AT0072783A AT383349B (de) 1982-03-12 1983-03-02 Verfahren zur herstellung von neuen 1-substituierten n-(8 alpha -ergolinyl)-n'-n'di|thylharnstoffen
GB08305735A GB2116548B (en) 1982-03-12 1983-03-02 Ergolinylureas
NL8300829A NL8300829A (nl) 1982-03-12 1983-03-07 1-gesubstitueerde n-(8alfa-ergolinyl)-n',n'-diethylurea en werkwijze ter bereiding daarvan.
IT19935/83A IT1161209B (it) 1982-03-12 1983-03-07 N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse
FI830754A FI830754L (fi) 1982-03-12 1983-03-07 Foerfarande foer framstaellning av 1-substituerade n-(8 -ergolinyl-n',n'-dietylkarbamider
SE8301257A SE452321B (sv) 1982-03-12 1983-03-08 1-substituerade n-(8alfa-ergolinyl)-n' ,n'-dietylkarbamider och sett att framstella desamma
AU12167/83A AU555961B2 (en) 1982-03-12 1983-03-08 1-substituted n-(8alpha-ergolinyl)-n:,n:-diethylureas
CA000423264A CA1203531A (en) 1982-03-12 1983-03-10 1-substituted n-(8 alfa-ergolinyl)-n',n' diethyl- ureas and processes for producing thereof
BE0/210287A BE896122A (fr) 1982-03-12 1983-03-10 N-(8alpha-ergolinyl)-n',n'-diethylurees substituees en position 1 et leurs procedes de preparation
CH1351/83A CH652125A5 (de) 1982-03-12 1983-03-11 1-substituierte n-(8alpha-ergolinyl)-n',n'-diaethylharnstoffe und verfahren zur herstellung derselben.
DE3308719A DE3308719A1 (de) 1982-03-12 1983-03-11 1-substituierte n-(8(alpha)-ergolinyl)-n'.n'-diethylharnstoffe, ihre herstellung und pharmakologische verwendung
FR8304005A FR2523131B1 (fr) 1982-03-12 1983-03-11 N-(8a-ergolinyl)-n', n'-diethylurees substituees en 1 et procede d'obtention de ces composes
JP58039349A JPS58180484A (ja) 1982-03-12 1983-03-11 １−置換Ｎ−／８α−エルゴリニル／−Ｎ′，Ｎ′−ジエチルウレア及びその製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Publications (1)

Publication Number Publication Date
CS231214B1 true CS231214B1 (en) 1984-10-15

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Country Status (15)

Country Link
JP (1) JPS58180484A (da)
AT (1) AT383349B (da)
AU (1) AU555961B2 (da)
BE (1) BE896122A (da)
CA (1) CA1203531A (da)
CH (1) CH652125A5 (da)
CS (1) CS231214B1 (da)
DE (1) DE3308719A1 (da)
DK (1) DK84683A (da)
FI (1) FI830754L (da)
FR (1) FR2523131B1 (da)
GB (1) GB2116548B (da)
IT (1) IT1161209B (da)
NL (1) NL8300829A (da)
SE (1) SE452321B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3623503A1 (de) * 1986-07-09 1988-01-21 Schering Ag 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne
WO2012062676A1 (de) * 2010-11-11 2012-05-18 Sinoxa Pharma Ug Lisurid, tergurid und derivate davon zur verwendung in der prophylaxe und/oder therapie fibrotischer veränderungen
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
AT231082B (de) * 1960-10-12 1964-01-10 Sandoz Ag Verfahren zur Herstellung von neuen Harnstoff-Derivaten
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
CA1203531A (en) 1986-04-22
SE452321B (sv) 1987-11-23
GB2116548B (en) 1985-03-20
AU555961B2 (en) 1986-10-16
NL8300829A (nl) 1983-10-03
GB8305735D0 (en) 1983-04-07
ATA72783A (de) 1986-11-15
AT383349B (de) 1987-06-25
FR2523131B1 (fr) 1987-08-28
FI830754A0 (fi) 1983-03-07
JPS58180484A (ja) 1983-10-21
DE3308719A1 (de) 1983-09-22
FR2523131A1 (fr) 1983-09-16
IT8319935A0 (it) 1983-03-07
FI830754L (fi) 1983-09-13
SE8301257L (sv) 1983-09-13
AU1216783A (en) 1983-09-15
DK84683D0 (da) 1983-02-24
IT1161209B (it) 1987-03-18
SE8301257D0 (sv) 1983-03-08
DK84683A (da) 1983-09-13
CH652125A5 (de) 1985-10-31
BE896122A (fr) 1983-07-01
GB2116548A (en) 1983-09-28

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