IT1161209B - N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse - Google Patents
N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesseInfo
- Publication number
- IT1161209B IT1161209B IT19935/83A IT1993583A IT1161209B IT 1161209 B IT1161209 B IT 1161209B IT 19935/83 A IT19935/83 A IT 19935/83A IT 1993583 A IT1993583 A IT 1993583A IT 1161209 B IT1161209 B IT 1161209B
- Authority
- IT
- Italy
- Prior art keywords
- ergolini
- dietilure
- 8alfa
- replaced
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS821734A CS231214B1 (en) | 1982-03-12 | 1982-03-12 | Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8319935A0 IT8319935A0 (it) | 1983-03-07 |
IT1161209B true IT1161209B (it) | 1987-03-18 |
Family
ID=5352449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT19935/83A IT1161209B (it) | 1982-03-12 | 1983-03-07 | N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS58180484A (it) |
AT (1) | AT383349B (it) |
AU (1) | AU555961B2 (it) |
BE (1) | BE896122A (it) |
CA (1) | CA1203531A (it) |
CH (1) | CH652125A5 (it) |
CS (1) | CS231214B1 (it) |
DE (1) | DE3308719A1 (it) |
DK (1) | DK84683A (it) |
FI (1) | FI830754L (it) |
FR (1) | FR2523131B1 (it) |
GB (1) | GB2116548B (it) |
IT (1) | IT1161209B (it) |
NL (1) | NL8300829A (it) |
SE (1) | SE452321B (it) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3309493A1 (de) * | 1983-03-14 | 1984-09-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel |
EP0208417A3 (en) * | 1985-06-12 | 1989-09-06 | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu | Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis |
DE3522894A1 (de) * | 1985-06-24 | 1987-01-02 | Schering Ag | Verwendung von tergurid als geriatrikum |
FR2584720B1 (fr) * | 1985-07-11 | 1987-10-02 | Rhone Poulenc Sante | Procede de preparation de derives n-methyles de l'ergoline |
DE3620293A1 (de) * | 1986-06-16 | 1987-12-17 | Schering Ag | 1-und/oder 2-substituierte ergolinderivate |
DE3623503A1 (de) * | 1986-07-09 | 1988-01-21 | Schering Ag | 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel |
DE10212564B4 (de) * | 2002-03-12 | 2007-04-19 | Neurobiotec Gmbh | 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne |
WO2012062676A1 (de) * | 2010-11-11 | 2012-05-18 | Sinoxa Pharma Ug | Lisurid, tergurid und derivate davon zur verwendung in der prophylaxe und/oder therapie fibrotischer veränderungen |
US9657020B2 (en) | 2015-01-20 | 2017-05-23 | Xoc Pharmaceuticals, Inc. | Ergoline compounds and uses thereof |
BR112017015510A2 (pt) | 2015-01-20 | 2018-01-30 | Xoc Pharmaceuticals Inc | composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo |
CA3064274A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH344731A (de) * | 1956-05-18 | 1960-02-29 | Sandoz Ag | Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe |
AT231082B (de) * | 1960-10-12 | 1964-01-10 | Sandoz Ag | Verfahren zur Herstellung von neuen Harnstoff-Derivaten |
EP0021206B1 (de) * | 1979-06-13 | 1983-06-22 | Schering Aktiengesellschaft | Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel |
-
1982
- 1982-03-12 CS CS821734A patent/CS231214B1/cs unknown
-
1983
- 1983-02-24 DK DK84683A patent/DK84683A/da not_active Application Discontinuation
- 1983-03-02 AT AT0072783A patent/AT383349B/de not_active IP Right Cessation
- 1983-03-02 GB GB08305735A patent/GB2116548B/en not_active Expired
- 1983-03-07 FI FI830754A patent/FI830754L/fi not_active Application Discontinuation
- 1983-03-07 NL NL8300829A patent/NL8300829A/nl not_active Application Discontinuation
- 1983-03-07 IT IT19935/83A patent/IT1161209B/it active
- 1983-03-08 SE SE8301257A patent/SE452321B/sv not_active IP Right Cessation
- 1983-03-08 AU AU12167/83A patent/AU555961B2/en not_active Ceased
- 1983-03-10 CA CA000423264A patent/CA1203531A/en not_active Expired
- 1983-03-10 BE BE0/210287A patent/BE896122A/fr not_active IP Right Cessation
- 1983-03-11 JP JP58039349A patent/JPS58180484A/ja active Pending
- 1983-03-11 CH CH1351/83A patent/CH652125A5/de not_active IP Right Cessation
- 1983-03-11 DE DE3308719A patent/DE3308719A1/de not_active Withdrawn
- 1983-03-11 FR FR8304005A patent/FR2523131B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GB2116548B (en) | 1985-03-20 |
AU1216783A (en) | 1983-09-15 |
NL8300829A (nl) | 1983-10-03 |
BE896122A (fr) | 1983-07-01 |
GB2116548A (en) | 1983-09-28 |
FI830754L (fi) | 1983-09-13 |
SE452321B (sv) | 1987-11-23 |
IT8319935A0 (it) | 1983-03-07 |
CA1203531A (en) | 1986-04-22 |
AT383349B (de) | 1987-06-25 |
AU555961B2 (en) | 1986-10-16 |
GB8305735D0 (en) | 1983-04-07 |
JPS58180484A (ja) | 1983-10-21 |
DK84683D0 (da) | 1983-02-24 |
SE8301257D0 (sv) | 1983-03-08 |
ATA72783A (de) | 1986-11-15 |
FR2523131B1 (fr) | 1987-08-28 |
CS231214B1 (en) | 1984-10-15 |
DK84683A (da) | 1983-09-13 |
FI830754A0 (fi) | 1983-03-07 |
SE8301257L (sv) | 1983-09-13 |
DE3308719A1 (de) | 1983-09-22 |
FR2523131A1 (fr) | 1983-09-16 |
CH652125A5 (de) | 1985-10-31 |
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