BE896122A - N-(8alpha-ergolinyl)-n',n'-diethylurees substituees en position 1 et leurs procedes de preparation - Google Patents

N-(8alpha-ergolinyl)-n',n'-diethylurees substituees en position 1 et leurs procedes de preparation

Info

Publication number
BE896122A
BE896122A BE0/210287A BE210287A BE896122A BE 896122 A BE896122 A BE 896122A BE 0/210287 A BE0/210287 A BE 0/210287A BE 210287 A BE210287 A BE 210287A BE 896122 A BE896122 A BE 896122A
Authority
BE
Belgium
Prior art keywords
diethylurees
ergolinyl
8alpha
substituted
preparation methods
Prior art date
Application number
BE0/210287A
Other languages
English (en)
French (fr)
Inventor
A Cenry
J Krepelka
K Rezabek
M Seda
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of BE896122A publication Critical patent/BE896122A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/210287A 1982-03-12 1983-03-10 N-(8alpha-ergolinyl)-n',n'-diethylurees substituees en position 1 et leurs procedes de preparation BE896122A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Publications (1)

Publication Number Publication Date
BE896122A true BE896122A (fr) 1983-07-01

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/210287A BE896122A (fr) 1982-03-12 1983-03-10 N-(8alpha-ergolinyl)-n',n'-diethylurees substituees en position 1 et leurs procedes de preparation

Country Status (15)

Country Link
JP (1) JPS58180484A (da)
AT (1) AT383349B (da)
AU (1) AU555961B2 (da)
BE (1) BE896122A (da)
CA (1) CA1203531A (da)
CH (1) CH652125A5 (da)
CS (1) CS231214B1 (da)
DE (1) DE3308719A1 (da)
DK (1) DK84683A (da)
FI (1) FI830754L (da)
FR (1) FR2523131B1 (da)
GB (1) GB2116548B (da)
IT (1) IT1161209B (da)
NL (1) NL8300829A (da)
SE (1) SE452321B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3623503A1 (de) * 1986-07-09 1988-01-21 Schering Ag 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne
WO2012062676A1 (de) * 2010-11-11 2012-05-18 Sinoxa Pharma Ug Lisurid, tergurid und derivate davon zur verwendung in der prophylaxe und/oder therapie fibrotischer veränderungen
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
AT231082B (de) * 1960-10-12 1964-01-10 Sandoz Ag Verfahren zur Herstellung von neuen Harnstoff-Derivaten
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
CA1203531A (en) 1986-04-22
SE452321B (sv) 1987-11-23
GB2116548B (en) 1985-03-20
AU555961B2 (en) 1986-10-16
NL8300829A (nl) 1983-10-03
GB8305735D0 (en) 1983-04-07
ATA72783A (de) 1986-11-15
AT383349B (de) 1987-06-25
FR2523131B1 (fr) 1987-08-28
FI830754A0 (fi) 1983-03-07
JPS58180484A (ja) 1983-10-21
DE3308719A1 (de) 1983-09-22
FR2523131A1 (fr) 1983-09-16
IT8319935A0 (it) 1983-03-07
CS231214B1 (en) 1984-10-15
FI830754L (fi) 1983-09-13
SE8301257L (sv) 1983-09-13
AU1216783A (en) 1983-09-15
DK84683D0 (da) 1983-02-24
IT1161209B (it) 1987-03-18
SE8301257D0 (sv) 1983-03-08
DK84683A (da) 1983-09-13
CH652125A5 (de) 1985-10-31
GB2116548A (en) 1983-09-28

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SPOFA SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYRODU

Effective date: 19880331