CS224645B2 - Method for producing substituted 3-aminosydnonimine - Google Patents

Method for producing substituted 3-aminosydnonimine Download PDF

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Publication number
CS224645B2
CS224645B2 CS821412A CS141282A CS224645B2 CS 224645 B2 CS224645 B2 CS 224645B2 CS 821412 A CS821412 A CS 821412A CS 141282 A CS141282 A CS 141282A CS 224645 B2 CS224645 B2 CS 224645B2
Authority
CS
Czechoslovakia
Prior art keywords
group
formula
methyl
acid
acid addition
Prior art date
Application number
CS821412A
Other languages
Czech (cs)
English (en)
Inventor
Karl Dr Schoenafinger
Rudi Dr Beyerle
Helmut Dr Bohn
Melitta Dr Just
Piero A Dr Martorana
Rolf Eberhard Dr Nitz
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Publication of CS224645B2 publication Critical patent/CS224645B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Epoxy Compounds (AREA)
  • Seasonings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS821412A 1981-03-02 1982-03-02 Method for producing substituted 3-aminosydnonimine CS224645B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813107933 DE3107933A1 (de) 1981-03-02 1981-03-02 Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
CS224645B2 true CS224645B2 (en) 1984-01-16

Family

ID=6126174

Family Applications (1)

Application Number Title Priority Date Filing Date
CS821412A CS224645B2 (en) 1981-03-02 1982-03-02 Method for producing substituted 3-aminosydnonimine

Country Status (23)

Country Link
US (2) US4436743A (ko)
EP (1) EP0059356B1 (ko)
JP (1) JPS57158768A (ko)
KR (1) KR880001428B1 (ko)
AT (1) ATE13055T1 (ko)
AU (1) AU545292B2 (ko)
CA (1) CA1192905A (ko)
CS (1) CS224645B2 (ko)
DD (1) DD208617A5 (ko)
DE (2) DE3107933A1 (ko)
DK (1) DK149852C (ko)
ES (1) ES510015A0 (ko)
FI (1) FI820518L (ko)
HU (1) HU190683B (ko)
IL (1) IL65141A (ko)
NO (1) NO820476L (ko)
NZ (1) NZ199862A (ko)
PH (1) PH18696A (ko)
PL (1) PL136818B1 (ko)
PT (1) PT74507B (ko)
RO (1) RO84816B (ko)
SU (1) SU1097197A3 (ko)
ZA (1) ZA821327B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なｎ−アシルシドノンイミン誘導体およびその製法
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
DK243084A (da) * 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
DE3526068A1 (de) * 1985-07-20 1987-01-22 Cassella Ag Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische praeparate
DE3702083A1 (de) * 1987-01-24 1988-08-04 Cassella Ag Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3732174A1 (de) * 1987-09-24 1989-04-06 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
US5221680A (en) * 1988-01-14 1993-06-22 Cassella Aktiengesellschaft Substituted 3-aminosydnonimines
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
US5120732A (en) * 1988-06-14 1992-06-09 Cassella Aktiengesellschaft Substituted 3-aminosyndone imines, a process for their preparation and their use
DE4025604A1 (de) * 1990-08-13 1992-02-20 Cassella Ag 3-dicyclohexylamino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4028679A1 (de) * 1990-09-10 1992-03-19 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4031373A1 (de) * 1990-10-04 1992-04-09 Cassella Ag 3-piperazino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
EP0903346A1 (en) * 1995-11-06 1999-03-24 Chugai Seiyaku Kabushiki Kaisha Sydnone imine derivatives
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US6531158B1 (en) 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695897C3 (de) 1966-07-04 1979-02-15 Takeda Chemical Industries Ltd N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3833580A (en) 1966-08-09 1974-09-03 Boehringer Sohn Ingelheim 3-morpholino-n6-cyclohexylcarbonyl sydnonimine
BE788052A (fr) * 1971-08-26 1973-02-26 Science Union & Cie Societe Fr Nouveaux derives de la sydnone imine
US3833589A (en) * 1972-07-31 1974-09-03 Sandoz Ag Substituted sydnonimine nitrate esters
DE2930736A1 (de) * 1979-07-28 1981-02-12 Cassella Ag Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5832870A (ja) * 1981-08-24 1983-02-25 Hiroyoshi Hidaka 新規なシドノンイミン誘導体及びその製法
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なｎ−アシルシドノンイミン誘導体およびその製法

Also Published As

Publication number Publication date
SU1097197A3 (ru) 1984-06-07
CA1192905A (en) 1985-09-03
ES8303404A1 (es) 1983-02-01
ATE13055T1 (de) 1985-05-15
DE3107933A1 (de) 1982-09-16
PH18696A (en) 1985-09-05
DE3263342D1 (en) 1985-06-05
PL235274A1 (ko) 1982-10-25
RO84816B (ro) 1984-09-30
DD208617A5 (de) 1984-04-04
NO820476L (no) 1982-09-03
DK149852C (da) 1987-06-01
IL65141A (en) 1984-10-31
RO84816A (ro) 1984-08-17
HU190683B (en) 1986-10-28
PT74507B (de) 1983-11-08
KR830009062A (ko) 1983-12-17
AU8096682A (en) 1982-09-16
KR880001428B1 (ko) 1988-08-08
EP0059356A1 (de) 1982-09-08
PL136818B1 (en) 1986-03-31
PT74507A (de) 1982-04-01
ZA821327B (en) 1983-01-26
US4551454A (en) 1985-11-05
ES510015A0 (es) 1983-02-01
FI820518L (fi) 1982-09-03
JPS57158768A (en) 1982-09-30
NZ199862A (en) 1985-04-30
EP0059356B1 (de) 1985-05-02
IL65141A0 (en) 1982-05-31
DK67682A (da) 1982-09-03
AU545292B2 (en) 1985-07-11
US4436743A (en) 1984-03-13
DK149852B (da) 1986-10-13

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