DK67682A - Fremgangsmaade til fremstilling af substituerede 3-aminosydnoniminer eller syreadditionssalte deraf samt disse forbindelsers anvendelse mod cardiovaskulaere sygdomme - Google Patents

Fremgangsmaade til fremstilling af substituerede 3-aminosydnoniminer eller syreadditionssalte deraf samt disse forbindelsers anvendelse mod cardiovaskulaere sygdomme Download PDF

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Publication number
DK67682A
DK67682A DK67682A DK67682A DK67682A DK 67682 A DK67682 A DK 67682A DK 67682 A DK67682 A DK 67682A DK 67682 A DK67682 A DK 67682A DK 67682 A DK67682 A DK 67682A
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Prior art keywords
addition salts
synonymines
substituted
amino
procedure
Prior art date
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DK67682A
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English (en)
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DK149852C (da
DK149852B (da
Inventor
K Schoenafinger
R Beyerle
H Bohn
M Just
R-E Nitz
Original Assignee
Cassella Ag
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Publication of DK67682A publication Critical patent/DK67682A/da
Publication of DK149852B publication Critical patent/DK149852B/da
Application granted granted Critical
Publication of DK149852C publication Critical patent/DK149852C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/041,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Seasonings (AREA)
DK67682A 1981-03-02 1982-02-16 Analogifremgangsmaade til fremstilling af substituerede 3-aminosydnoniminer eller et farmakologisk acceptabelt syreadditionssalt deraf DK149852C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3107933 1981-03-02
DE19813107933 DE3107933A1 (de) 1981-03-02 1981-03-02 Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Publications (3)

Publication Number Publication Date
DK67682A true DK67682A (da) 1982-09-03
DK149852B DK149852B (da) 1986-10-13
DK149852C DK149852C (da) 1987-06-01

Family

ID=6126174

Family Applications (1)

Application Number Title Priority Date Filing Date
DK67682A DK149852C (da) 1981-03-02 1982-02-16 Analogifremgangsmaade til fremstilling af substituerede 3-aminosydnoniminer eller et farmakologisk acceptabelt syreadditionssalt deraf

Country Status (23)

Country Link
US (2) US4436743A (da)
EP (1) EP0059356B1 (da)
JP (1) JPS57158768A (da)
KR (1) KR880001428B1 (da)
AT (1) ATE13055T1 (da)
AU (1) AU545292B2 (da)
CA (1) CA1192905A (da)
CS (1) CS224645B2 (da)
DD (1) DD208617A5 (da)
DE (2) DE3107933A1 (da)
DK (1) DK149852C (da)
ES (1) ES510015A0 (da)
FI (1) FI820518L (da)
HU (1) HU190683B (da)
IL (1) IL65141A (da)
NO (1) NO820476L (da)
NZ (1) NZ199862A (da)
PH (1) PH18696A (da)
PL (1) PL136818B1 (da)
PT (1) PT74507B (da)
RO (1) RO84816B (da)
SU (1) SU1097197A3 (da)
ZA (1) ZA821327B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なn−アシルシドノンイミン誘導体およびその製法
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
DK243084A (da) * 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
DE3526068A1 (de) * 1985-07-20 1987-01-22 Cassella Ag Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische praeparate
DE3702083A1 (de) * 1987-01-24 1988-08-04 Cassella Ag Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3732174A1 (de) * 1987-09-24 1989-04-06 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
US5221680A (en) * 1988-01-14 1993-06-22 Cassella Aktiengesellschaft Substituted 3-aminosydnonimines
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
US5120732A (en) * 1988-06-14 1992-06-09 Cassella Aktiengesellschaft Substituted 3-aminosyndone imines, a process for their preparation and their use
DE4025604A1 (de) * 1990-08-13 1992-02-20 Cassella Ag 3-dicyclohexylamino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4028679A1 (de) * 1990-09-10 1992-03-19 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4031373A1 (de) * 1990-10-04 1992-04-09 Cassella Ag 3-piperazino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
WO1997017334A1 (fr) * 1995-11-06 1997-05-15 Chugai Seiyaku Kabushiki Kaisha Derives d'imine de sydnone
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US6531158B1 (en) 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695897C3 (de) 1966-07-04 1979-02-15 Takeda Chemical Industries Ltd N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3833580A (en) 1966-08-09 1974-09-03 Boehringer Sohn Ingelheim 3-morpholino-n6-cyclohexylcarbonyl sydnonimine
BE788052A (fr) * 1971-08-26 1973-02-26 Science Union & Cie Societe Fr Nouveaux derives de la sydnone imine
US3833589A (en) * 1972-07-31 1974-09-03 Sandoz Ag Substituted sydnonimine nitrate esters
DE2930736A1 (de) * 1979-07-28 1981-02-12 Cassella Ag Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5832870A (ja) * 1981-08-24 1983-02-25 Hiroyoshi Hidaka 新規なシドノンイミン誘導体及びその製法
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なn−アシルシドノンイミン誘導体およびその製法

Also Published As

Publication number Publication date
SU1097197A3 (ru) 1984-06-07
PL235274A1 (da) 1982-10-25
NO820476L (no) 1982-09-03
US4551454A (en) 1985-11-05
RO84816B (ro) 1984-09-30
DE3263342D1 (en) 1985-06-05
PH18696A (en) 1985-09-05
ES8303404A1 (es) 1983-02-01
KR880001428B1 (ko) 1988-08-08
DD208617A5 (de) 1984-04-04
FI820518L (fi) 1982-09-03
US4436743A (en) 1984-03-13
DK149852C (da) 1987-06-01
KR830009062A (ko) 1983-12-17
DE3107933A1 (de) 1982-09-16
ES510015A0 (es) 1983-02-01
ZA821327B (en) 1983-01-26
EP0059356A1 (de) 1982-09-08
HU190683B (en) 1986-10-28
IL65141A (en) 1984-10-31
NZ199862A (en) 1985-04-30
IL65141A0 (en) 1982-05-31
PT74507A (de) 1982-04-01
AU8096682A (en) 1982-09-16
RO84816A (ro) 1984-08-17
JPS57158768A (en) 1982-09-30
EP0059356B1 (de) 1985-05-02
DK149852B (da) 1986-10-13
ATE13055T1 (de) 1985-05-15
AU545292B2 (en) 1985-07-11
PT74507B (de) 1983-11-08
CS224645B2 (en) 1984-01-16
PL136818B1 (en) 1986-03-31
CA1192905A (en) 1985-09-03

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