HUP0003463A2 - Piperidinil-metil-oxazolidinon-származék, eljárás ennek előállítására és a vegyületet tartalmazó gyógyszerkészítmény - Google Patents

Piperidinil-metil-oxazolidinon-származék, eljárás ennek előállítására és a vegyületet tartalmazó gyógyszerkészítmény

Info

Publication number
HUP0003463A2
HUP0003463A2 HU0003463A HUP0003463A HUP0003463A2 HU P0003463 A2 HUP0003463 A2 HU P0003463A2 HU 0003463 A HU0003463 A HU 0003463A HU P0003463 A HUP0003463 A HU P0003463A HU P0003463 A2 HUP0003463 A2 HU P0003463A2
Authority
HU
Hungary
Prior art keywords
piperidinylmethyloxazolidinone
derivative
preparation
same
pharmaceutical compositions
Prior art date
Application number
HU0003463A
Other languages
English (en)
Inventor
Gerd Bartoszyk
Rudolf Gottschlich
Joachim Leibrock
Helmut Prücher
Christoph Seyfried
Original Assignee
Merck Patent Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh. filed Critical Merck Patent Gmbh.
Publication of HUP0003463A2 publication Critical patent/HUP0003463A2/hu
Publication of HUP0003463A3 publication Critical patent/HUP0003463A3/hu
Publication of HU224317B1 publication Critical patent/HU224317B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

A találmány tárgya (I) képletű 5-[4-(4-fluor-benzil)-piperidin-1-il-metil]-3-(4-hidroxi-fenil)-oxazolidin-2-on és fiziológiailagelfogadható sói. A találmány szerinti vegyület neuroleptikus hatású. Ó
HU0003463A 1997-09-09 1998-08-26 Egy piperidinil-metil-oxazolidinon-származék, eljárás előállítására az ezt tartalmazó gyógyszerkészítmények és alkalmazása HU224317B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19739332A DE19739332C1 (de) 1997-09-09 1997-09-09 Piperidinylmethyloxazolidinon-Derivat
PCT/EP1998/005402 WO1999012924A1 (de) 1997-09-09 1998-08-26 Piperidinylmethyloxazolidinon-derivat

Publications (3)

Publication Number Publication Date
HUP0003463A2 true HUP0003463A2 (hu) 2002-01-28
HUP0003463A3 HUP0003463A3 (en) 2002-02-28
HU224317B1 HU224317B1 (hu) 2005-07-28

Family

ID=7841621

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003463A HU224317B1 (hu) 1997-09-09 1998-08-26 Egy piperidinil-metil-oxazolidinon-származék, eljárás előállítására az ezt tartalmazó gyógyszerkészítmények és alkalmazása

Country Status (23)

Country Link
US (1) US6413989B1 (hu)
EP (1) EP1015447B1 (hu)
JP (1) JP2001515898A (hu)
KR (1) KR20010023742A (hu)
CN (1) CN1146563C (hu)
AR (1) AR010942A1 (hu)
AT (1) ATE215947T1 (hu)
AU (1) AU745519B2 (hu)
BR (1) BR9811759A (hu)
CA (1) CA2302669C (hu)
DE (2) DE19739332C1 (hu)
DK (1) DK1015447T3 (hu)
ES (1) ES2172918T3 (hu)
HU (1) HU224317B1 (hu)
ID (1) ID24218A (hu)
NO (1) NO20001202L (hu)
PL (1) PL338777A1 (hu)
PT (1) PT1015447E (hu)
RU (1) RU2203896C2 (hu)
SK (1) SK283177B6 (hu)
TW (1) TW457243B (hu)
WO (1) WO1999012924A1 (hu)
ZA (1) ZA988206B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03004652A (es) 2000-12-21 2003-09-05 Warner Lambert Co Derivados de piperidina como antagonistas selectivos de subtipo de n-metil-d-aspartato.
MXPA02002749A (es) 2001-03-27 2002-10-28 Warner Lambert Co Derivados de ciclohexilamina como antagonistas del subtipo selectivo del n-metil-d-aspartato.
US7651970B2 (en) * 2005-12-20 2010-01-26 Chevron U.S.A. Inc. Regeneration of ionic liquid catalyst by hydrogenation using a metal or metal alloy catalyst
JP5683489B2 (ja) * 2009-01-12 2015-03-11 アレイ バイオファーマ、インコーポレイテッド ピペリジン含有化合物およびその用途
RU2469023C1 (ru) * 2011-06-22 2012-12-10 Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН) Равномерно меченный тритием 4-[2-(4-бензилпиперидин-1-ил-гидроксипропил] фенол

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3723797A1 (de) * 1987-07-18 1989-01-26 Merck Patent Gmbh Oxazolidinone
DE19531321A1 (de) * 1995-08-25 1997-02-27 Merck Patent Gmbh Piperidinylmethyloxazolidinone

Also Published As

Publication number Publication date
JP2001515898A (ja) 2001-09-25
WO1999012924A1 (de) 1999-03-18
PT1015447E (pt) 2002-09-30
CN1269799A (zh) 2000-10-11
DE19739332C1 (de) 1998-11-26
AU9265198A (en) 1999-03-29
EP1015447A1 (de) 2000-07-05
NO20001202D0 (no) 2000-03-08
CN1146563C (zh) 2004-04-21
DE59803765D1 (de) 2002-05-16
ES2172918T3 (es) 2002-10-01
DK1015447T3 (da) 2002-06-17
SK283177B6 (sk) 2003-03-04
CA2302669C (en) 2008-04-22
ATE215947T1 (de) 2002-04-15
AR010942A1 (es) 2000-07-12
AU745519B2 (en) 2002-03-21
ZA988206B (en) 2000-03-09
HUP0003463A3 (en) 2002-02-28
SK2982000A3 (en) 2000-07-11
RU2203896C2 (ru) 2003-05-10
NO20001202L (no) 2000-03-08
PL338777A1 (en) 2000-11-20
US20020061912A1 (en) 2002-05-23
HU224317B1 (hu) 2005-07-28
US6413989B1 (en) 2002-07-02
EP1015447B1 (de) 2002-04-10
CA2302669A1 (en) 1999-03-18
KR20010023742A (ko) 2001-03-26
BR9811759A (pt) 2000-08-29
TW457243B (en) 2001-10-01
ID24218A (id) 2000-07-13

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Legal Events

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HFG4 Patent granted, date of granting

Effective date: 20050613

MM4A Lapse of definitive patent protection due to non-payment of fees