ATE400552T1 - 4,4' -dithiobis- (3-aminobutane-1-sulfonate)- derivate und sie enthaltende zusammensetzungen - Google Patents
4,4' -dithiobis- (3-aminobutane-1-sulfonate)- derivate und sie enthaltende zusammensetzungenInfo
- Publication number
- ATE400552T1 ATE400552T1 AT03753648T AT03753648T ATE400552T1 AT E400552 T1 ATE400552 T1 AT E400552T1 AT 03753648 T AT03753648 T AT 03753648T AT 03753648 T AT03753648 T AT 03753648T AT E400552 T1 ATE400552 T1 AT E400552T1
- Authority
- AT
- Austria
- Prior art keywords
- aminobutane
- dithiobis
- sulfonate
- derivatives
- compositions containing
- Prior art date
Links
- HJPXZXVKLGEMGP-UHFFFAOYSA-N 3-amino-4-[(2-amino-4-sulfobutyl)disulfanyl]butane-1-sulfonic acid Chemical class OS(=O)(=O)CCC(N)CSSCC(N)CCS(O)(=O)=O HJPXZXVKLGEMGP-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0208977A FR2842522B1 (fr) | 2002-07-16 | 2002-07-16 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositons les contenant |
| FR0303425A FR2852597A1 (fr) | 2003-03-20 | 2003-03-20 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE400552T1 true ATE400552T1 (de) | 2008-07-15 |
Family
ID=30117028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03753648T ATE400552T1 (de) | 2002-07-16 | 2003-07-16 | 4,4' -dithiobis- (3-aminobutane-1-sulfonate)- derivate und sie enthaltende zusammensetzungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7235687B2 (de) |
| EP (1) | EP1525188B1 (de) |
| AT (1) | ATE400552T1 (de) |
| AU (1) | AU2003271811A1 (de) |
| CY (1) | CY1109013T1 (de) |
| DE (1) | DE60322064D1 (de) |
| DK (1) | DK1525188T3 (de) |
| ES (1) | ES2309336T3 (de) |
| PT (1) | PT1525188E (de) |
| SI (1) | SI1525188T1 (de) |
| WO (1) | WO2004007441A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107663538B (zh) | 2005-04-15 | 2022-03-18 | Epi基因组股份公司 | 分析细胞增殖性病症的方法和核酸 |
| FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| EP2322514A1 (de) * | 2009-11-11 | 2011-05-18 | Bayer Schering Pharma Aktiengesellschaft | Homoglutaminsäure und Glutaminsäurederivate |
| EP2439192A1 (de) * | 2010-10-07 | 2012-04-11 | Quantum Genomics | Verfahren zur Herstellung von (3S,3S') 4,4'-disulfandiylbis (3-aminobutan 1-sulfonsäure) |
| CA2859704C (en) * | 2011-12-21 | 2020-04-28 | Quantum Genomics | Combination of (3s,3s') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent |
| EP2722327A1 (de) * | 2012-10-22 | 2014-04-23 | Quantum Genomics | Kristalline Phase von (3S,3S') 4,4'-disulfandiylbis (3-Aminobutan 1-Sulfonsäure) mit L-Lysin |
| CA2964474A1 (en) * | 2014-10-17 | 2016-04-21 | University Of Florida Research Foundation | Novel small molecule anticancer agents |
| US10501426B1 (en) | 2019-01-11 | 2019-12-10 | King Saud University | Synthesis of thiazole derivative as anticancer and anti-antibiotics resistant bacteria agent |
| CN110845347B (zh) * | 2019-11-21 | 2021-10-15 | 利尔化学股份有限公司 | 一种氯代高丝氨酸烷基酯的制备方法 |
| TW202207917A (zh) | 2020-05-06 | 2022-03-01 | 法商量子基因科技有限公司 | 包含腦胺肽酶抑制劑、利尿劑及全身性腎素－血管收縮素系統阻斷劑之醫藥組合物 |
| WO2022225712A1 (en) | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
| CN115448833B (zh) * | 2022-08-25 | 2024-07-05 | 湖北泰盛化工有限公司 | 一种多官能团脂肪族伯醇衍生物的羟基直接氯代方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2773712B1 (fr) | 1998-01-16 | 2000-06-02 | Inst Nat Sante Rech Med | Composition pharmaceutique comprenant au moins un inhibiteur de l'aminopeptidase a |
-
2003
- 2003-07-16 DE DE60322064T patent/DE60322064D1/de not_active Expired - Lifetime
- 2003-07-16 AU AU2003271811A patent/AU2003271811A1/en not_active Abandoned
- 2003-07-16 AT AT03753648T patent/ATE400552T1/de active
- 2003-07-16 ES ES03753648T patent/ES2309336T3/es not_active Expired - Lifetime
- 2003-07-16 US US10/521,171 patent/US7235687B2/en not_active Expired - Lifetime
- 2003-07-16 SI SI200331379T patent/SI1525188T1/sl unknown
- 2003-07-16 DK DK03753648T patent/DK1525188T3/da active
- 2003-07-16 PT PT03753648T patent/PT1525188E/pt unknown
- 2003-07-16 EP EP03753648A patent/EP1525188B1/de not_active Expired - Lifetime
- 2003-07-16 WO PCT/FR2003/002242 patent/WO2004007441A2/fr not_active Ceased
-
2008
- 2008-10-07 CY CY20081101109T patent/CY1109013T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1109013T1 (el) | 2014-07-02 |
| DE60322064D1 (de) | 2008-08-21 |
| AU2003271811A8 (en) | 2004-02-02 |
| SI1525188T1 (sl) | 2008-12-31 |
| AU2003271811A1 (en) | 2004-02-02 |
| EP1525188B1 (de) | 2008-07-09 |
| PT1525188E (pt) | 2008-10-16 |
| ES2309336T3 (es) | 2008-12-16 |
| US7235687B2 (en) | 2007-06-26 |
| DK1525188T3 (da) | 2008-11-17 |
| WO2004007441A2 (fr) | 2004-01-22 |
| US20060135602A1 (en) | 2006-06-22 |
| WO2004007441A3 (fr) | 2004-04-08 |
| EP1525188A2 (de) | 2005-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1525188 Country of ref document: EP |
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| EEIH | Change in the person of patent owner |