CS202035B2 - Process for preparing new p-hydroxyphenoxypropanolamines - Google Patents

Process for preparing new p-hydroxyphenoxypropanolamines Download PDF

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Publication number
CS202035B2
CS202035B2 CS75986A CS98675A CS202035B2 CS 202035 B2 CS202035 B2 CS 202035B2 CS 75986 A CS75986 A CS 75986A CS 98675 A CS98675 A CS 98675A CS 202035 B2 CS202035 B2 CS 202035B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
formula
compounds
compound
hydrogen
Prior art date
Application number
CS75986A
Other languages
Czech (cs)
English (en)
Inventor
Enar I Carlsson
Nils H A Persson
Gustav B R Samuelsson
Kjell I L Wetterlin
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to CS785580A priority Critical patent/CS202037B2/cs
Publication of CS202035B2 publication Critical patent/CS202035B2/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS75986A 1974-02-14 1975-02-14 Process for preparing new p-hydroxyphenoxypropanolamines CS202035B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS785580A CS202037B2 (en) 1974-02-14 1978-08-28 Process for preparing new p-hydroxyphenoxypropanolamines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7401958A SE388849B (sv) 1974-02-14 1974-02-14 Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan

Publications (1)

Publication Number Publication Date
CS202035B2 true CS202035B2 (en) 1980-12-31

Family

ID=20320208

Family Applications (2)

Application Number Title Priority Date Filing Date
CS75986A CS202035B2 (en) 1974-02-14 1975-02-14 Process for preparing new p-hydroxyphenoxypropanolamines
CS785579A CS202036B2 (en) 1974-02-14 1978-08-28 Process for preparing new p-hydroxyphenoxypropanolamines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS785579A CS202036B2 (en) 1974-02-14 1978-08-28 Process for preparing new p-hydroxyphenoxypropanolamines

Country Status (23)

Country Link
US (2) US4244969A (fr)
JP (1) JPS50116433A (fr)
AT (1) AT334881B (fr)
AU (1) AU497441B2 (fr)
BE (1) BE825515A (fr)
CA (1) CA1052387A (fr)
CH (1) CH616648A5 (fr)
CS (2) CS202035B2 (fr)
DD (1) DD118614A5 (fr)
DE (1) DE2502993A1 (fr)
DK (1) DK135711B (fr)
FI (1) FI62055B (fr)
FR (1) FR2261000B1 (fr)
GB (1) GB1492647A (fr)
HU (1) HU169704B (fr)
IE (1) IE41350B1 (fr)
IT (1) IT7950875A0 (fr)
LU (1) LU71846A1 (fr)
NL (1) NL7501785A (fr)
NO (1) NO140628C (fr)
SE (1) SE388849B (fr)
SU (3) SU603332A3 (fr)
ZA (1) ZA75381B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
SE8004088L (sv) 1980-06-02 1981-12-03 Haessle Ab Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
CA1262729A (fr) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
SE457505B (sv) * 1984-01-10 1989-01-09 Lejus Medical Ab Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
ES2005525T3 (es) * 1987-03-26 1992-10-01 Helopharm W. Petrik Gmbh & Co.Kg. Procedimiento para la fabricacion de 5-hidroxi-diprafenona y sus sales con acidos.
SG99290A1 (en) * 1996-04-09 2003-10-27 Nps Pharma Inc Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
US5966498A (en) * 1996-08-07 1999-10-12 Lakewood Engineering And Manufacturing Company End closure assembly for oil-filled heater
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
JP4604583B2 (ja) * 2004-07-20 2011-01-05 ダイソー株式会社 １−アミド−３−（２−ヒドロキシフェノキシ）−２−プロパノール誘導体、ならびに２−アミドメチル−１，４−ベンゾジオキサン誘導体の製造法
IL165365A0 (en) 2004-11-24 2006-01-15 Q Core Ltd Finger-type peristaltic pump
JP4934287B2 (ja) * 2005-04-05 2012-05-16 花王株式会社 美白剤
FR2916441B1 (fr) * 2007-05-22 2009-08-28 Clariant Specialty Fine Chem Procede de racemisation d'alpha-aminoacetals optiquement actifs.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301580A (fr) * 1962-12-11
GB1069345A (en) * 1963-07-19 1967-05-17 Ici Ltd New alkanolamine derivatives
DE1922003C3 (de) * 1969-04-30 1979-10-11 Boehringer Mannheim Gmbh, 6800 Mannheim N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz
BE790165A (fr) * 1971-12-14 1973-02-15 Parke Davis & Co Nouveaux aminoalcanols et procede pour les preparer

Also Published As

Publication number Publication date
AT334881B (de) 1977-02-10
NO750468L (fr) 1975-08-15
AU7811675A (en) 1976-08-12
ZA75381B (en) 1976-01-28
NO140628C (no) 1979-10-10
SU603332A3 (ru) 1978-04-15
BE825515A (fr) 1975-08-14
SE388849B (sv) 1976-10-18
CH616648A5 (fr) 1980-04-15
IE41350L (en) 1975-08-14
ATA96475A (de) 1976-06-15
DK135711C (fr) 1977-11-21
FI750390A (fr) 1975-08-15
DE2502993A1 (de) 1975-09-04
JPS50116433A (fr) 1975-09-11
SE7401958L (fr) 1975-08-15
IE41350B1 (en) 1979-12-19
LU71846A1 (fr) 1975-12-09
SU609460A3 (ru) 1978-05-30
CA1052387A (fr) 1979-04-10
US4336267A (en) 1982-06-22
DK135711B (da) 1977-06-13
IT7950875A0 (it) 1979-11-21
HU169704B (fr) 1977-02-28
CS202036B2 (en) 1980-12-31
DK53975A (fr) 1975-10-06
SU577971A3 (ru) 1977-10-25
FR2261000A1 (fr) 1975-09-12
US4244969A (en) 1981-01-13
NL7501785A (nl) 1975-08-18
FR2261000B1 (fr) 1978-07-21
DD118614A5 (fr) 1976-03-12
AU497441B2 (en) 1978-12-14
FI62055B (fi) 1982-07-30
NO140628B (no) 1979-07-02
GB1492647A (en) 1977-11-23

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