CS188883B2 - Method of producing novel derivatives of penicillin - Google Patents

Method of producing novel derivatives of penicillin

Info

Publication number
CS188883B2
CS188883B2 CS727048A CS704872A CS188883B2 CS 188883 B2 CS188883 B2 CS 188883B2 CS 727048 A CS727048 A CS 727048A CS 704872 A CS704872 A CS 704872A CS 188883 B2 CS188883 B2 CS 188883B2
Authority
CS
Czechoslovakia
Prior art keywords
penicillin
novel derivatives
producing novel
producing
derivatives
Prior art date
Application number
CS727048A
Other languages
Czech (cs)
English (en)
Inventor
Hans-Bodo Koenig
Wilfried Schroeck
Karl-Georg Metzger
Original Assignee
Koenig Hans Bodo
Wilfried Schroeck
Metzger Karl Georg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koenig Hans Bodo, Wilfried Schroeck, Metzger Karl Georg filed Critical Koenig Hans Bodo
Publication of CS188883B2 publication Critical patent/CS188883B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
CS727048A 1971-10-23 1972-10-19 Method of producing novel derivatives of penicillin CS188883B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2152967A DE2152967C3 (de) 1971-10-23 1971-10-23 Acylureidopenicilline

Publications (1)

Publication Number Publication Date
CS188883B2 true CS188883B2 (en) 1979-03-30

Family

ID=5823251

Family Applications (1)

Application Number Title Priority Date Filing Date
CS727048A CS188883B2 (en) 1971-10-23 1972-10-19 Method of producing novel derivatives of penicillin

Country Status (31)

Country Link
JP (2) JPS55391B2 (fr)
AR (1) AR195805A1 (fr)
AT (1) AT320152B (fr)
BE (1) BE790440A (fr)
BG (2) BG20813A3 (fr)
CA (1) CA1019323A (fr)
CH (1) CH579089A5 (fr)
CS (1) CS188883B2 (fr)
CY (1) CY947A (fr)
DD (1) DD106044B3 (fr)
DE (1) DE2152967C3 (fr)
DK (1) DK134992C (fr)
EG (1) EG10826A (fr)
ES (1) ES407851A1 (fr)
FI (1) FI56839C (fr)
FR (1) FR2157908B1 (fr)
GB (1) GB1392849A (fr)
HK (1) HK18578A (fr)
HU (1) HU167986B (fr)
IE (1) IE37123B1 (fr)
IL (1) IL40628A (fr)
KE (1) KE2824A (fr)
LU (1) LU66332A1 (fr)
NO (1) NO143909C (fr)
PH (1) PH9893A (fr)
PL (2) PL89056B1 (fr)
RO (2) RO60670A (fr)
SE (1) SE412236B (fr)
SU (1) SU527139A3 (fr)
YU (1) YU264072A (fr)
ZA (1) ZA727473B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972870A (en) * 1971-10-23 1976-08-03 Bayer Aktiengesellschaft Penicillins
US3974142A (en) * 1971-10-23 1976-08-10 Bayer Aktiengesellschaft Penicillins
NL175419C (nl) * 1971-10-23 1984-11-01 Bayer Ag Werkwijze ter bereiding of vervaardiging van antibiotisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van antibiotisch werkzame alfa-gesubstitueerde 6-(alfa-(3-acylureido)acetylamino) penicillanzuurderivaten.
US3983105A (en) * 1971-10-23 1976-09-28 Bayer Aktiengesellschaft Penicillins
US3972869A (en) * 1971-10-23 1976-08-03 Bayer Aktiengesellschaft Penicillins
US3974141A (en) * 1971-10-23 1976-08-10 Bayer Aktiengesellschaft Penicillins
US3978056A (en) * 1971-10-23 1976-08-31 Bayer Aktiengesellschaft Penicillins
US4009272A (en) * 1971-10-23 1977-02-22 Bayer Aktiengesellschaft Penicillins
DE2258973A1 (de) * 1972-12-01 1974-06-06 Bayer Ag Penicilline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS587637B2 (ja) * 1973-12-27 1983-02-10 住友化学工業株式会社 シンキペニシリンノ セイホウ
DE2407715C2 (de) * 1974-02-18 1982-12-02 Bayer Ag, 5090 Leverkusen Cephalosporine, Verfahren zu ihrer Herstellung sowie Arzneimittel
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
DE2525541C2 (de) * 1975-06-07 1984-01-12 Bayer Ag, 5090 Leverkusen β-Lactam-Antibiotica, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel
DE2810083A1 (de) 1978-03-08 1979-09-20 Bayer Ag Beta-lactam-verbindungen
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EP1780213A1 (fr) * 2005-10-27 2007-05-02 3M Innovative Properties Company Silicium-urée-azolides, leur préparation et leur utilisation dans la préparation d'isocyanates de silicone
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
EA019085B1 (ru) 2007-09-14 2014-01-30 Янссен Фармасьютикалз, Инк. 1',3-двузамещенные 4-(арил-х-фенил)-1н-пиридин-2-оны
SI2203439T1 (sl) 2007-09-14 2011-05-31 Ortho Mcneil Janssen Pharm 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni
ES2409215T3 (es) 2007-09-14 2013-06-25 Janssen Pharmaceuticals, Inc. 4-fenil-1H-piridin-2-onas 1-3-disustituidas
RU2492170C9 (ru) 2007-11-14 2013-12-27 Орто-Макнейл-Янссен Фармасьютикалз, Инк. Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2
BRPI0918055A2 (pt) 2008-09-02 2015-12-01 Addex Pharmaceuticals Sa derivados de 3-azabiciclo[3,1,0]hexila como moduladores de receptores metabotrópicos de glutamato.
WO2010043396A1 (fr) 2008-10-16 2010-04-22 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Dérivés d’indole et de benzomorpholine en tant que modulateurs des récepteurs métabotropiques du glutamate
CN102232074B (zh) 2008-11-28 2014-12-03 奥梅-杨森制药有限公司 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物
BRPI1010831A2 (pt) 2009-05-12 2016-04-05 Addex Pharmaceuticals Sa derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
ME01573B (me) 2009-05-12 2014-09-20 Addex Pharma Sa DERIVATI 1,2,4-TRIAZOLO[4,3-a]PIRIDINA I NJIHOVA UPOTREBA U TRETMANU ILI PREVENCIJI NEUROLOŠKIH I PSIHIJATRIJSKIH POREMEĆAJA
KR20120034721A (ko) * 2009-06-10 2012-04-12 테크필즈 바이오켐 코., 엘티디. 항균제 및 항균제-관련 화합물의 고투과 조성물 또는 전구약물
US8993591B2 (en) 2010-11-08 2015-03-31 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
WO2012062751A1 (fr) 2010-11-08 2012-05-18 Janssen Pharmaceuticals, Inc. Dérivés de 1,2,4-triazolo[4,3-a]pyridine et leur utilisation en tant que modulateurs allostériques positifs des récepteurs mglur2
JP5852664B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
SI3431106T1 (sl) 2014-01-21 2021-03-31 Janssen Pharmaceutica Nv Kombinacije, ki vsebujejo pozitivne alosterične modulatorje metabotropnega glutamatergičnega receptorja podtipa 2 in njihova uporaba
LT3096790T (lt) 2014-01-21 2019-10-10 Janssen Pharmaceutica, N.V. Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770620A1 (de) * 1968-06-12 1971-11-11 Bayer Ag Neue Penicilline

Also Published As

Publication number Publication date
JPS4849910A (fr) 1973-07-14
IE37123L (en) 1973-04-23
NO143909B (no) 1981-01-26
FR2157908B1 (fr) 1976-03-19
FR2157908A1 (fr) 1973-06-08
JPS4849787A (fr) 1973-07-13
GB1392849A (en) 1975-04-30
CH579089A5 (fr) 1976-08-31
DE2152967A1 (de) 1973-05-03
ES407851A1 (es) 1975-10-01
AU4806472A (en) 1974-04-26
IL40628A0 (en) 1972-12-29
KE2824A (en) 1978-04-07
SE412236B (sv) 1980-02-25
FI56839B (fi) 1979-12-31
HU167986B (fr) 1976-02-28
CY947A (en) 1978-06-23
FI56839C (fi) 1980-04-10
NO143909C (no) 1981-05-06
RO60670A (fr) 1976-10-15
BG20813A3 (fr) 1975-12-20
YU264072A (en) 1982-06-18
DE2152967C3 (de) 1981-11-19
ZA727473B (en) 1973-07-25
DK134992B (da) 1977-02-21
LU66332A1 (fr) 1973-01-23
CA1019323A (en) 1977-10-18
PL93574B1 (fr) 1977-06-30
IL40628A (en) 1976-08-31
PH9893A (en) 1976-06-08
DD106044A5 (fr) 1974-05-20
IE37123B1 (en) 1977-05-11
BG21609A3 (fr) 1976-07-20
JPS55391B2 (fr) 1980-01-08
AT320152B (de) 1975-01-27
DD106044B3 (de) 1990-07-18
BE790440A (fr) 1973-04-24
HK18578A (en) 1978-04-14
DK134992C (da) 1977-07-18
SU527139A3 (ru) 1976-08-30
RO63066A (fr) 1978-06-15
AR195805A1 (es) 1973-11-09
PL89056B1 (fr) 1976-10-30
JPS57843B2 (fr) 1982-01-08
EG10826A (en) 1976-12-31
DE2152967B2 (de) 1981-02-19

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