CR20230104A - Compuestos y métodos para el tratamiento de infecciones virales - Google Patents

Compuestos y métodos para el tratamiento de infecciones virales

Info

Publication number
CR20230104A
CR20230104A CR20230104A CR20230104A CR20230104A CR 20230104 A CR20230104 A CR 20230104A CR 20230104 A CR20230104 A CR 20230104A CR 20230104 A CR20230104 A CR 20230104A CR 20230104 A CR20230104 A CR 20230104A
Authority
CR
Costa Rica
Prior art keywords
compounds
treatment
methods
viral infections
singly
Prior art date
Application number
CR20230104A
Other languages
English (en)
Inventor
Byoung-Kwon Chun
Richard L Mackman
Kassibla E Dempah
Hon C Hui
Rao V Kalla
Elaine Bunyan
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of CR20230104A publication Critical patent/CR20230104A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen compuestos y métodos de uso de dichos compuestos, solos o en combinación con agentes adicionales y sales, formas cristalinas, composiciones farmacéuticas de dichos compuestos para el tratamiento de infecciones virales.
CR20230104A 2020-08-27 2021-08-26 Compuestos y métodos para el tratamiento de infecciones virales CR20230104A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063071134P 2020-08-27 2020-08-27
US202163162283P 2021-03-17 2021-03-17
US202163215310P 2021-06-25 2021-06-25
PCT/US2021/047800 WO2022047065A2 (en) 2020-08-27 2021-08-26 Compounds and methods for treatment of viral infections

Publications (1)

Publication Number Publication Date
CR20230104A true CR20230104A (es) 2023-04-28

Family

ID=77775035

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20230104A CR20230104A (es) 2020-08-27 2021-08-26 Compuestos y métodos para el tratamiento de infecciones virales

Country Status (18)

Country Link
US (2) US11926645B2 (es)
EP (1) EP4204421B1 (es)
JP (1) JP2023540225A (es)
KR (1) KR20230057411A (es)
AU (2) AU2021331214B2 (es)
CA (1) CA3190702A1 (es)
CL (1) CL2023000555A1 (es)
CO (1) CO2023002071A2 (es)
CR (1) CR20230104A (es)
DK (1) DK4204421T3 (es)
DO (1) DOP2023000041A (es)
FI (1) FI4204421T3 (es)
IL (1) IL300453A (es)
LT (1) LT4204421T (es)
MX (1) MX2023002195A (es)
PE (1) PE20231983A1 (es)
TW (2) TW202233204A (es)
WO (1) WO2022047065A2 (es)

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CN114573590B (zh) * 2022-03-18 2023-11-14 苏州旺山旺水生物医药有限公司 一种四异丁酰基核苷类似物的制备方法及用途
CN116891474A (zh) * 2022-03-31 2023-10-17 苏州旺山旺水生物医药有限公司 一种单异丁酰基核苷类似物的制备方法
WO2023193715A1 (zh) * 2022-04-06 2023-10-12 深圳安泰维生物医药有限公司 一种组合物及其制备方法和用途
TW202345800A (zh) * 2022-04-06 2023-12-01 美商維納拓爾斯製藥公司 口服生物可利用的核苷類似物
CN114437159B (zh) * 2022-04-11 2022-06-28 佛山市晨康生物科技有限公司 一种环状碳酸酯核苷类化合物及其应用
CN114805402A (zh) * 2022-05-13 2022-07-29 深圳安泰维生物医药有限公司 一种口服抗冠状病毒感染药物的大规模制备方法
CN117924294A (zh) * 2022-05-17 2024-04-26 上海建毅腾创生物医药科技有限公司 氘代核苷化合物及其应用
WO2023227106A1 (zh) * 2022-05-27 2023-11-30 深圳安泰维生物医药有限公司 一种核苷类衍生化合物的药物组合物及其制备方法和用途
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