CR11201A - Derivados de pirimidina trisustituida para el tratamiento de enfermedades proliferativas - Google Patents
Derivados de pirimidina trisustituida para el tratamiento de enfermedades proliferativasInfo
- Publication number
- CR11201A CR11201A CR11201A CR11201A CR11201A CR 11201 A CR11201 A CR 11201A CR 11201 A CR11201 A CR 11201A CR 11201 A CR11201 A CR 11201A CR 11201 A CR11201 A CR 11201A
- Authority
- CR
- Costa Rica
- Prior art keywords
- treatment
- proliferative diseases
- trisustituida
- pirimidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de formula (I) o una sal farmaceuticas aceptable del mismo, procesos para su preparacion, composiciones farmaceuticas que los contienen y su uso en terapia, por ejemplo en el tratamiento de enfermedades proliferativas como el cancer y particularmente en una enfermadad mediada por una mTOR quinasa y/o una o mas enzimas P13K.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94856607P | 2007-07-09 | 2007-07-09 | |
US3029708P | 2008-02-21 | 2008-02-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR11201A true CR11201A (es) | 2010-06-17 |
Family
ID=40010883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR11201A CR11201A (es) | 2007-07-09 | 2010-01-08 | Derivados de pirimidina trisustituida para el tratamiento de enfermedades proliferativas |
Country Status (20)
Country | Link |
---|---|
US (1) | US20090018134A1 (es) |
EP (1) | EP2074118A2 (es) |
JP (1) | JP2010533158A (es) |
KR (1) | KR20100031639A (es) |
CN (1) | CN101801962A (es) |
AR (1) | AR067478A1 (es) |
AU (1) | AU2008273889B2 (es) |
BR (1) | BRPI0814818A2 (es) |
CA (1) | CA2692945A1 (es) |
CL (1) | CL2008002006A1 (es) |
CO (1) | CO6390066A2 (es) |
CR (1) | CR11201A (es) |
DO (1) | DOP2010000011A (es) |
EA (1) | EA201000092A1 (es) |
NI (1) | NI201000004A (es) |
PE (1) | PE20090773A1 (es) |
TW (1) | TW200904813A (es) |
UY (1) | UY31215A1 (es) |
WO (1) | WO2009007748A2 (es) |
ZA (1) | ZA201000106B (es) |
Families Citing this family (80)
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US8946204B2 (en) | 2009-05-07 | 2015-02-03 | Gruenenthal Gmbh | Substituted phenylureas and phenylamides as vanilloid receptor ligands |
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US20140163023A1 (en) | 2011-04-04 | 2014-06-12 | Cellzome Limited | Dihydropyrrolo pyrimidine derivatives as mtor inhibitors |
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BR112015026257B1 (pt) | 2013-04-17 | 2022-12-20 | Signal Pharmaceuticals, Llc | Uso de um composto dihidropirazino-pirazina e enzalutamida, composição farmacêutica que os compreende, e kit |
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US7772271B2 (en) * | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
AU2006284751A1 (en) * | 2005-09-01 | 2007-03-08 | Array Biopharma Inc. | Raf inhibitor compounds and methods of use thereof |
GB0520657D0 (en) * | 2005-10-11 | 2005-11-16 | Ludwig Inst Cancer Res | Pharmaceutical compounds |
MX2009002046A (es) * | 2006-08-24 | 2009-03-06 | Astrazeneca Ab | Derivados de morfolino pirimidina utiles en el tratamiento de trastornos proliferativos. |
BRPI0814688A2 (pt) * | 2007-07-09 | 2017-06-06 | Astrazeneca Ab | composto, uso de um composto, métodos para produzir um efeito antiproliferativo em um animal de sangue quente, e para tratar doenças, e, composição farmacêutica |
WO2009007749A2 (en) * | 2007-07-09 | 2009-01-15 | Astrazeneca Ab | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases |
-
2008
- 2008-07-08 BR BRPI0814818A patent/BRPI0814818A2/pt not_active IP Right Cessation
- 2008-07-08 EP EP08776181A patent/EP2074118A2/en not_active Withdrawn
- 2008-07-08 EA EA201000092A patent/EA201000092A1/ru unknown
- 2008-07-08 AR ARP080102944A patent/AR067478A1/es unknown
- 2008-07-08 AU AU2008273889A patent/AU2008273889B2/en not_active Expired - Fee Related
- 2008-07-08 CA CA 2692945 patent/CA2692945A1/en not_active Abandoned
- 2008-07-08 JP JP2010515600A patent/JP2010533158A/ja active Pending
- 2008-07-08 WO PCT/GB2008/050546 patent/WO2009007748A2/en active Application Filing
- 2008-07-08 CN CN200880106248A patent/CN101801962A/zh active Pending
- 2008-07-08 KR KR1020107002969A patent/KR20100031639A/ko not_active Application Discontinuation
- 2008-07-09 US US12/170,128 patent/US20090018134A1/en not_active Abandoned
- 2008-07-09 CL CL2008002006A patent/CL2008002006A1/es unknown
- 2008-07-09 TW TW097125962A patent/TW200904813A/zh unknown
- 2008-07-09 UY UY31215A patent/UY31215A1/es unknown
- 2008-07-09 PE PE2008001149A patent/PE20090773A1/es not_active Application Discontinuation
-
2010
- 2010-01-06 ZA ZA2010/00106A patent/ZA201000106B/en unknown
- 2010-01-08 CR CR11201A patent/CR11201A/es not_active Application Discontinuation
- 2010-01-08 NI NI201000004A patent/NI201000004A/es unknown
- 2010-01-08 DO DO2010000011A patent/DOP2010000011A/es unknown
- 2010-02-09 CO CO10014104A patent/CO6390066A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2008273889A1 (en) | 2009-01-15 |
KR20100031639A (ko) | 2010-03-23 |
CA2692945A1 (en) | 2009-01-15 |
AR067478A1 (es) | 2009-10-14 |
WO2009007748A3 (en) | 2009-04-23 |
DOP2010000011A (es) | 2010-03-31 |
AU2008273889B2 (en) | 2012-03-08 |
WO2009007748A2 (en) | 2009-01-15 |
US20090018134A1 (en) | 2009-01-15 |
NI201000004A (es) | 2010-10-12 |
EA201000092A1 (ru) | 2010-06-30 |
UY31215A1 (es) | 2009-03-02 |
BRPI0814818A2 (pt) | 2019-09-10 |
CL2008002006A1 (es) | 2009-06-26 |
CN101801962A (zh) | 2010-08-11 |
PE20090773A1 (es) | 2009-07-23 |
ZA201000106B (en) | 2011-06-29 |
TW200904813A (en) | 2009-02-01 |
EP2074118A2 (en) | 2009-07-01 |
JP2010533158A (ja) | 2010-10-21 |
CO6390066A2 (es) | 2012-02-29 |
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