CO6990739A2 - Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal - Google Patents
Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la salInfo
- Publication number
- CO6990739A2 CO6990739A2 CO14138315A CO14138315A CO6990739A2 CO 6990739 A2 CO6990739 A2 CO 6990739A2 CO 14138315 A CO14138315 A CO 14138315A CO 14138315 A CO14138315 A CO 14138315A CO 6990739 A2 CO6990739 A2 CO 6990739A2
- Authority
- CO
- Colombia
- Prior art keywords
- lipids
- salt
- tear film
- sensitive emulsion
- emulsion system
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568089P | 2011-12-07 | 2011-12-07 | |
| US201261625401P | 2012-04-17 | 2012-04-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6990739A2 true CO6990739A2 (es) | 2014-07-10 |
Family
ID=47459152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO14138315A CO6990739A2 (es) | 2011-12-07 | 2014-06-26 | Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US9314528B2 (enExample) |
| EP (5) | EP2787969B1 (enExample) |
| JP (1) | JP6142419B2 (enExample) |
| KR (1) | KR102017922B1 (enExample) |
| CN (2) | CN104114152A (enExample) |
| AR (1) | AR089123A1 (enExample) |
| AU (2) | AU2012347459A1 (enExample) |
| BR (1) | BR112014013820A2 (enExample) |
| CA (1) | CA2858574C (enExample) |
| CL (1) | CL2014001518A1 (enExample) |
| CO (1) | CO6990739A2 (enExample) |
| DK (2) | DK2787968T3 (enExample) |
| ES (2) | ES2896336T3 (enExample) |
| HU (2) | HUE057140T2 (enExample) |
| IL (1) | IL233008A (enExample) |
| IN (1) | IN2014CN04809A (enExample) |
| MX (1) | MX355216B (enExample) |
| MY (1) | MY173378A (enExample) |
| PH (2) | PH12021553172A1 (enExample) |
| PL (2) | PL2787968T3 (enExample) |
| PT (2) | PT2787969T (enExample) |
| RU (1) | RU2014127074A (enExample) |
| SG (1) | SG11201403013VA (enExample) |
| SI (2) | SI2787968T1 (enExample) |
| TW (1) | TWI652072B (enExample) |
| WO (2) | WO2013086449A1 (enExample) |
| ZA (1) | ZA201404228B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8957048B2 (en) * | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| ES2706535T3 (es) | 2016-07-07 | 2019-03-29 | Salvat Lab Sa | Composiciones oftálmicas que comprenden aceite de ricino y triglicéridos de cadena media |
| JP2019524892A (ja) | 2016-08-19 | 2019-09-05 | アクリビスタ エルエルシーＡｋｒｉｖｉｓｔａ，Ｌｌｃ | ドライアイ症候群を診断及び治療する方法ならびにヒト眼を治療するための組成物 |
| CN111295169A (zh) | 2017-08-18 | 2020-06-16 | 阿克里维斯塔有限责任公司 | 诊断和治疗干眼综合症的方法和用于治疗人类眼睛的组合物 |
| US11096958B2 (en) | 2018-04-27 | 2021-08-24 | Allergan, Inc. | Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity |
| WO2025175150A1 (en) * | 2024-02-16 | 2025-08-21 | Allergan, Inc. | Enhanced artificial tear formulations |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201706A (en) | 1978-09-22 | 1980-05-06 | Burton, Parsons & Company, Inc. | Treatment of corneal edema |
| ATE6466T1 (de) | 1979-10-26 | 1984-03-15 | Smith And Nephew Associated Companies P.L.C. | Autoklavierbare emulsionen. |
| US5192535A (en) | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| IT1224795B (it) | 1988-12-01 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento |
| EP0436726B1 (en) | 1989-08-03 | 1993-10-20 | Eisai Co., Ltd. | Method of photostabilizing eyewash |
| US5681555A (en) | 1991-04-22 | 1997-10-28 | Gleich; Gerald J. | Method for the treatment of bronchial asthma by parenteral administration of anionic polymers |
| DE4229494A1 (de) | 1992-09-04 | 1994-03-10 | Basotherm Gmbh | Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks |
| CN1160346A (zh) | 1994-09-14 | 1997-09-24 | 大正制药株式会社 | 用于修复角膜损伤的滴眼液 |
| US5980865A (en) | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
| FI106923B (fi) | 1997-01-03 | 2001-05-15 | Cultor Ltd Finnsugar Bioproduc | Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa |
| AR002194A1 (es) | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| IT1302307B1 (it) | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
| WO2000029030A1 (en) | 1998-11-13 | 2000-05-25 | Continental Projects Limited | Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions |
| JP2000159659A (ja) * | 1998-11-30 | 2000-06-13 | Kazuo Tsubota | 眼科用人工涙液 |
| US6228392B1 (en) | 1999-04-29 | 2001-05-08 | Gene Tools, Llc | Osmotic delivery composition, solution, and method |
| PT2153819E (pt) | 2000-07-14 | 2012-11-14 | Allergan Inc | Utilização de um componente para aumento de solubilidade numa composição aquosa compreendendo tartarato de brimonidina |
| CA2355814C (en) | 2000-09-14 | 2010-06-29 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pharmaceutical composition for ophthalmic use |
| PT1339418E (pt) | 2000-11-08 | 2009-10-30 | Fxs Ventures Llc | Soluções oftálmicas e para lentes de contacto melhoradas contendo sacarídeos simples como intensificadores de conservação |
| US7045121B2 (en) | 2001-12-14 | 2006-05-16 | Allergan, Inc. | Ophthalmic compositions for lubricating eyes and methods for making and using same |
| JP2006504701A (ja) | 2002-09-30 | 2006-02-09 | マーク・エー・バビザイェフ | 眼疾患の局所的治療方法、並びに、その治療用組成物及び治療用手段 |
| DE60323520D1 (de) * | 2002-10-18 | 2008-10-23 | Joel S Echols | Dreischichtige tränenformulierung |
| US20040137079A1 (en) | 2003-01-08 | 2004-07-15 | Cook James N. | Contact lens and eye drop rewetter compositions and methods |
| US6635654B1 (en) * | 2003-01-09 | 2003-10-21 | Allergan, Inc. | Ophthalmic compositions containing loratadine |
| US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
| EP1611883A1 (en) | 2003-03-26 | 2006-01-04 | Menicon Co., Ltd. | Composition for ophthalmic use |
| KR20120062846A (ko) * | 2003-06-13 | 2012-06-14 | 알콘, 인코퍼레이티드 | 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물 |
| TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| US20050009836A1 (en) | 2003-06-26 | 2005-01-13 | Laskar Paul A. | Ophthalmic composition containing quinolones and method of use |
| KR20060121151A (ko) * | 2003-11-10 | 2006-11-28 | 도레이 가부시끼가이샤 | 다당류 함유 조성물 및 누액층 안정화 점안제 |
| US8569367B2 (en) * | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
| WO2008035246A2 (en) * | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
| CN101896160A (zh) * | 2006-10-17 | 2010-11-24 | 阿勒根公司 | 环胞菌素组合物 |
| AU2008219600A1 (en) * | 2007-02-28 | 2008-09-04 | Aciex Therapeutics, Inc. | Methods and compositions for normalizing meibomian gland secretions |
| JP4929245B2 (ja) | 2008-07-31 | 2012-05-09 | 株式会社ベッセル工業 | 工具類のグリップ |
| CA2764802A1 (en) * | 2009-06-05 | 2010-12-09 | Allergan, Inc. | Artificial tears and therapeutic uses |
| WO2013049621A1 (en) * | 2011-09-29 | 2013-04-04 | The Board Of Regents Of The University Of Oklahoma | Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof |
| US8957048B2 (en) * | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
-
2012
- 2012-12-07 WO PCT/US2012/068615 patent/WO2013086449A1/en not_active Ceased
- 2012-12-07 CA CA2858574A patent/CA2858574C/en active Active
- 2012-12-07 WO PCT/US2012/068603 patent/WO2013086438A1/en not_active Ceased
- 2012-12-07 CN CN201280067685.0A patent/CN104114152A/zh active Pending
- 2012-12-07 ES ES12808607T patent/ES2896336T3/es active Active
- 2012-12-07 EP EP12808607.1A patent/EP2787969B1/en active Active
- 2012-12-07 RU RU2014127074A patent/RU2014127074A/ru unknown
- 2012-12-07 HU HUE12808607A patent/HUE057140T2/hu unknown
- 2012-12-07 PL PL12808606T patent/PL2787968T3/pl unknown
- 2012-12-07 EP EP20153344.5A patent/EP3666257A1/en not_active Withdrawn
- 2012-12-07 MY MYPI2014001672A patent/MY173378A/en unknown
- 2012-12-07 JP JP2014546154A patent/JP6142419B2/ja active Active
- 2012-12-07 AU AU2012347459A patent/AU2012347459A1/en not_active Abandoned
- 2012-12-07 PL PL12808607T patent/PL2787969T3/pl unknown
- 2012-12-07 PH PH1/2021/553172A patent/PH12021553172A1/en unknown
- 2012-12-07 MX MX2014006804A patent/MX355216B/es active IP Right Grant
- 2012-12-07 KR KR1020147018598A patent/KR102017922B1/ko not_active Expired - Fee Related
- 2012-12-07 HU HUE12808606A patent/HUE049489T2/hu unknown
- 2012-12-07 EP EP21198843.1A patent/EP3981387A1/en active Pending
- 2012-12-07 ES ES12808606T patent/ES2797650T3/es active Active
- 2012-12-07 PH PH1/2014/501296A patent/PH12014501296B1/en unknown
- 2012-12-07 PT PT128086071T patent/PT2787969T/pt unknown
- 2012-12-07 EP EP24167560.2A patent/EP4403220A3/en active Pending
- 2012-12-07 IN IN4809CHN2014 patent/IN2014CN04809A/en unknown
- 2012-12-07 DK DK12808606.3T patent/DK2787968T3/da active
- 2012-12-07 DK DK12808607.1T patent/DK2787969T3/da active
- 2012-12-07 EP EP12808606.3A patent/EP2787968B1/en active Active
- 2012-12-07 BR BR112014013820A patent/BR112014013820A2/pt not_active Application Discontinuation
- 2012-12-07 PT PT128086063T patent/PT2787968T/pt unknown
- 2012-12-07 SI SI201231783T patent/SI2787968T1/sl unknown
- 2012-12-07 US US13/708,771 patent/US9314528B2/en active Active
- 2012-12-07 US US13/708,783 patent/US20130150324A1/en not_active Abandoned
- 2012-12-07 TW TW101146304A patent/TWI652072B/zh not_active IP Right Cessation
- 2012-12-07 SI SI201231957T patent/SI2787969T1/sl unknown
- 2012-12-07 AR ARP120104614A patent/AR089123A1/es not_active Application Discontinuation
- 2012-12-07 CN CN201810890387.0A patent/CN108969482A/zh active Pending
- 2012-12-07 SG SG11201403013VA patent/SG11201403013VA/en unknown
-
2014
- 2014-06-08 IL IL233008A patent/IL233008A/en active IP Right Grant
- 2014-06-09 CL CL2014001518A patent/CL2014001518A1/es unknown
- 2014-06-09 ZA ZA2014/04228A patent/ZA201404228B/en unknown
- 2014-06-26 CO CO14138315A patent/CO6990739A2/es unknown
-
2017
- 2017-11-27 AU AU2017265181A patent/AU2017265181B2/en active Active
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