CO6990739A2 - Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal - Google Patents

Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal

Info

Publication number
CO6990739A2
CO6990739A2 CO14138315A CO14138315A CO6990739A2 CO 6990739 A2 CO6990739 A2 CO 6990739A2 CO 14138315 A CO14138315 A CO 14138315A CO 14138315 A CO14138315 A CO 14138315A CO 6990739 A2 CO6990739 A2 CO 6990739A2
Authority
CO
Colombia
Prior art keywords
lipids
salt
tear film
sensitive emulsion
emulsion system
Prior art date
Application number
CO14138315A
Other languages
English (en)
Inventor
Joseph G Vehige
Peter A Simmons
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47459152&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6990739(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CO6990739A2 publication Critical patent/CO6990739A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
CO14138315A 2011-12-07 2014-06-26 Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal CO6990739A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568089P 2011-12-07 2011-12-07
US201261625401P 2012-04-17 2012-04-17

Publications (1)

Publication Number Publication Date
CO6990739A2 true CO6990739A2 (es) 2014-07-10

Family

ID=47459152

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14138315A CO6990739A2 (es) 2011-12-07 2014-06-26 Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal

Country Status (28)

Country Link
US (2) US20130150324A1 (es)
EP (4) EP2787968B1 (es)
JP (1) JP6142419B2 (es)
KR (1) KR102017922B1 (es)
CN (2) CN104114152A (es)
AR (1) AR089123A1 (es)
AU (2) AU2012347459A1 (es)
BR (1) BR112014013820A2 (es)
CA (1) CA2858574C (es)
CL (1) CL2014001518A1 (es)
CO (1) CO6990739A2 (es)
DK (2) DK2787969T3 (es)
ES (2) ES2896336T3 (es)
HK (2) HK1201458A1 (es)
HU (2) HUE049489T2 (es)
IL (1) IL233008A (es)
IN (1) IN2014CN04809A (es)
MX (1) MX355216B (es)
MY (1) MY173378A (es)
PH (1) PH12014501296A1 (es)
PL (2) PL2787968T3 (es)
PT (2) PT2787969T (es)
RU (1) RU2014127074A (es)
SG (1) SG11201403013VA (es)
SI (2) SI2787968T1 (es)
TW (1) TWI652072B (es)
WO (2) WO2013086449A1 (es)
ZA (1) ZA201404228B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957048B2 (en) * 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
JOP20170147B1 (ar) 2016-07-07 2021-08-17 Salvat Lab Sa تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة
CN113244291A (zh) 2016-08-19 2021-08-13 阿克里维斯塔有限责任公司 诊断和治疗干眼综合症的方法以及用于治疗人眼的组合物
JP7311160B2 (ja) 2017-08-18 2023-07-19 アクリビスタ エルエルシー ドライアイ症候群を診断及び処置する方法及びヒトの眼を処置するための組成物
JP2021522264A (ja) 2018-04-27 2021-08-30 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 抗微生物有効性の増強及び毒性の減少を有する亜塩素酸ナトリウム組成物

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201706A (en) 1978-09-22 1980-05-06 Burton, Parsons & Company, Inc. Treatment of corneal edema
EP0028110B1 (en) * 1979-10-26 1984-03-07 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
IT1224795B (it) 1988-12-01 1990-10-24 Sigma Tau Ind Farmaceuti Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento
DK0436726T3 (da) 1989-08-03 1993-12-27 Eisai Co Ltd Fotostabil oftalmisk opløsning og fremgangsmåde til fremstilling deraf
US5681555A (en) 1991-04-22 1997-10-28 Gleich; Gerald J. Method for the treatment of bronchial asthma by parenteral administration of anionic polymers
DE4229494A1 (de) 1992-09-04 1994-03-10 Basotherm Gmbh Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks
KR970705985A (ko) 1994-09-14 1997-11-03 우에하라 아끼라 각막 장해 복구용 점안제(Eye Drops for Repairing Corneal Disturbance)
US5980865A (en) 1995-08-18 1999-11-09 Baker Norton Pharmaceuticals, Inc. Method for treating late phase allergic reactions and inflammatory diseases
FI106923B (fi) 1997-01-03 2001-05-15 Cultor Ltd Finnsugar Bioproduc Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa
AR002194A1 (es) 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
IT1302307B1 (it) 1998-09-01 2000-09-05 Sigma Tau Healthscience Spa Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
DE69919379T2 (de) 1998-11-13 2005-09-08 Continental Projects Ltd. Komplexe von hyaluronic saure/carnitinen und pharmazeutische und kosmetische zusammensetzungen
JP2000159659A (ja) * 1998-11-30 2000-06-13 Kazuo Tsubota 眼科用人工涙液
US6228392B1 (en) 1999-04-29 2001-05-08 Gene Tools, Llc Osmotic delivery composition, solution, and method
BR0112461A (pt) 2000-07-14 2003-07-22 Allergan Inc Composições que contém componentes terapeuticamente ativos tendo uma solubilidade aumentada
AU781975B2 (en) 2000-09-14 2005-06-23 Hayashibara Co., Ltd Pharmaceutical composition for ophthalmic use
AU2720602A (en) 2000-11-08 2002-05-21 Bio Concept Lab Improved ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
US7045121B2 (en) 2001-12-14 2006-05-16 Allergan, Inc. Ophthalmic compositions for lubricating eyes and methods for making and using same
EP1551399A4 (en) 2002-09-30 2011-01-05 Mark A Babizhayev METHOD FOR THE TOPICAL TREATMENT OF EYE DISEASES AND COMPOSITION AND DEVICE FOR THIS TREATMENT
BR0306662A (pt) * 2002-10-18 2005-02-22 Joel S Echols Formulação lacrimal de três camadas
US20040137079A1 (en) 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
US6635654B1 (en) * 2003-01-09 2003-10-21 Allergan, Inc. Ophthalmic compositions containing loratadine
WO2004084877A1 (ja) 2003-03-26 2004-10-07 Menicon Co., Ltd. 眼科用組成物
CA2527712C (en) * 2003-06-13 2014-08-05 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20050009836A1 (en) 2003-06-26 2005-01-13 Laskar Paul A. Ophthalmic composition containing quinolones and method of use
CA2549737A1 (en) * 2003-11-10 2005-05-26 Toray Industries, Inc. Polysaccharide-containing composition and tear film stabilizing ophthalmic solution
US8569367B2 (en) * 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
US7288520B2 (en) * 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
WO2008035246A2 (en) * 2006-07-28 2008-03-27 Novagali Pharma Sa Compositions containing quaternary ammonium compounds
CN101896160A (zh) * 2006-10-17 2010-11-24 阿勒根公司 环胞菌素组合物
JP2010520210A (ja) 2007-02-28 2010-06-10 アーシエックス セラピューティックス， インコーポレイテッド マイボーム腺分泌を正常化するための方法および組成物
JP4929245B2 (ja) 2008-07-31 2012-05-09 株式会社ベッセル工業 工具類のグリップ
CA2764802A1 (en) * 2009-06-05 2010-12-09 Allergan, Inc. Artificial tears and therapeutic uses
US8957048B2 (en) * 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye

Also Published As

Publication number Publication date
PH12014501296A1 (en) 2014-10-08
HUE057140T2 (hu) 2022-04-28
TW201325633A (zh) 2013-07-01
JP2015504860A (ja) 2015-02-16
HK1203057A1 (en) 2015-10-16
DK2787968T3 (da) 2020-06-02
PT2787968T (pt) 2020-06-16
AU2017265181B2 (en) 2019-06-20
AU2012347459A1 (en) 2014-07-03
US20130150324A1 (en) 2013-06-13
BR112014013820A8 (pt) 2017-06-13
IN2014CN04809A (es) 2015-09-18
EP2787968B1 (en) 2020-03-04
SG11201403013VA (en) 2014-07-30
CN108969482A (zh) 2018-12-11
AU2017265181A1 (en) 2017-12-14
PL2787969T3 (pl) 2021-12-20
BR112014013820A2 (pt) 2017-06-13
EP2787969B1 (en) 2021-09-29
IL233008A0 (en) 2014-07-31
RU2018119362A (ru) 2018-11-08
TWI652072B (zh) 2019-03-01
CA2858574C (en) 2017-05-30
KR20140107383A (ko) 2014-09-04
EP2787968A1 (en) 2014-10-15
MY173378A (en) 2020-01-21
ES2797650T3 (es) 2020-12-03
ES2896336T3 (es) 2022-02-24
KR102017922B1 (ko) 2019-09-03
JP6142419B2 (ja) 2017-06-07
EP3666257A1 (en) 2020-06-17
US20130197083A1 (en) 2013-08-01
HUE049489T2 (hu) 2020-09-28
PL2787968T3 (pl) 2020-08-24
WO2013086449A1 (en) 2013-06-13
RU2014127074A (ru) 2016-02-10
HK1201458A1 (en) 2015-09-04
AR089123A1 (es) 2014-07-30
US9314528B2 (en) 2016-04-19
WO2013086438A1 (en) 2013-06-13
RU2018119362A3 (es) 2021-09-07
IL233008A (en) 2017-07-31
CN104114152A (zh) 2014-10-22
MX2014006804A (es) 2014-09-22
PT2787969T (pt) 2021-11-09
EP3981387A1 (en) 2022-04-13
ZA201404228B (en) 2015-12-23
MX355216B (es) 2018-04-10
SI2787968T1 (sl) 2020-08-31
CA2858574A1 (en) 2013-06-13
EP2787969A1 (en) 2014-10-15
DK2787969T3 (da) 2021-11-01
SI2787969T1 (sl) 2021-12-31
CL2014001518A1 (es) 2014-10-24

Similar Documents

Publication Publication Date Title
CO6990739A2 (es) Administración eficiente de lípidos a la película lagrimal humana mediante el uso de un sistema de emulsión sensible a la sal
BR112013023618A2 (pt) sistema para controlar a propulsão de um veículo
BR112014006865A2 (pt) sistema para direcionar luz
CL2014000183A1 (es) Formulación farmacéutica que contienen anticuerpos anti-pcsk9; metodo para preparar dicha formulación.
CR20130406A (es) Composiciones farmacéuticas que comprenden anticuerpos humanos frente a pcsk9
DK3192501T3 (da) Topisk farmaceutisk sammensætning baseret på semifluorerede alkaner
FR2984278B1 (fr) Systeme d'assistance au pilote d'un aeronef par des moyens haptiques
BR112014000233A2 (pt) sistema de flape para uma aeronave
BR112013033110A2 (pt) sistema de composição para demarcação de pavimento
CO7010828A2 (es) Preparación farmacéutica que comprende ߖciclodextrina sustituida
BR112012023973A2 (pt) sistema configurado para monitorar reanimação cardiopulmonar
FR2973708B1 (fr) Dispositif d'assistance respiratoire
FR2995092B1 (fr) Systeme d'assistance a la tenue du vol stationnaire d'un helicoptere
BR112014006647A2 (pt) sistema adaptado para treinar um jogador desportivo
FI20115695A (fi) Lentoestevalaisin
DK2530780T3 (da) Fremgangsmåde til administration af et hybridsystems funktion
FR2971626B1 (fr) Film bi-couches d'un module photovoltaique
BR112014008339A2 (pt) sistema de cromatografia e utilização de um sistema de cromatografia e da proporção
FR2974243B1 (fr) Film bi-couches d'un module photovoltaique
CO6880061A2 (es) Método para tratar el cáncer mediante el uso combinado de fármacos
FR3009842B1 (fr) Procede d'assemblage de deux pales d'un distributeur de turbomachine
ES1075720Y (es) Aposito para cubrir el punto de puncion de un cateter
BR112013003942A2 (pt) "sistema de controle de asa"
FI10064U1 (fi) Järjestelmä käyttäjien esittelemiseksi toisilleen
FR2987124B1 (fr) Systeme d'ingestion de cendres volcaniques