CO6160334A2 - Metodo para la elaboracion de una vacuna de conbinacion para proteger contra polio - Google Patents
Metodo para la elaboracion de una vacuna de conbinacion para proteger contra polioInfo
- Publication number
- CO6160334A2 CO6160334A2 CO09023294A CO09023294A CO6160334A2 CO 6160334 A2 CO6160334 A2 CO 6160334A2 CO 09023294 A CO09023294 A CO 09023294A CO 09023294 A CO09023294 A CO 09023294A CO 6160334 A2 CO6160334 A2 CO 6160334A2
- Authority
- CO
- Colombia
- Prior art keywords
- units
- antigen
- vaccine
- percent
- inactivated poliovirus
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 8
- 229960005486 vaccine Drugs 0.000 title abstract 8
- 208000000474 Poliomyelitis Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 21
- 102000036639 antigens Human genes 0.000 abstract 21
- 108091007433 antigens Proteins 0.000 abstract 21
- 241000709701 Human poliovirus 1 Species 0.000 abstract 5
- 241000991587 Enterovirus C Species 0.000 abstract 3
- 241000709727 Human poliovirus 3 Species 0.000 abstract 3
- 229940001442 combination vaccine Drugs 0.000 abstract 2
- 229960003983 diphtheria toxoid Drugs 0.000 abstract 2
- 229960000814 tetanus toxoid Drugs 0.000 abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32671—Demonstrated in vivo effect
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
1.- Un método para la elaboración de una vacuna (es decir, una vacuna de combinación) que comprende el poliovirus inactivado tipo 1, el cual comprende los pasos de: mezclar toxoide de difteria y toxoide de tétanos, seguidos por la adición del poliovirus inactivado tipo 1 en una dosis mayor de 10 unidades de antígeno D y menos de 20 unidades de antígeno D, y opcionalmente los poliovirus inactivados tipos 2 y/o 3 (IPV). 2.- Un método para la elaboración de una vacuna (es decir, una vacuna de combinación) que comprende el poliovirus inactivado tipo 1, el cual comprende los pasos de: mezclar de toxoide de difteria y toxoide de tétanos, seguidos por la adición del poliovirus inactivado tipo 1 en una cantidad mayor de 10 unidades de antígeno D y menas de 20 unidades de antígeno D por 0.5 mililitros, y opcionalmente el poliovirus inactivado tipos 2 y/o 3 (IPV). 3.- El método de la reivindicación 1 ó 2, en donde la vacuna comprende el poliovirus inactivado tipo 1 en del 26 al 49 por ciento, del 30 al 45 por ciento, del 33 al 40 por ciento, o del 35 al 37 por ciento de una dosis estándar de 40 unidades de antígeno D. 4.- El método de la reivindicación 1 ó 2, en donde la vacuna comprende el poliovirus inactivado tipo 1 en del 26 al 49 por ciento, del 30 al 45 por ciento, del 33 al 40 por ciento, o del 35 al 37 por ciento de una dosis estándar de 40 unidades de antígeno D por 0.5 mililitros. 5.- El método de las reivindicaciones 1 a 4, en donde la vacuna comprende adicionalmente el poliovirus inactivado tipo 3 en una dosis de 8 a 20 unidades de antígeno D, de 9 a 19 unidades de antígeno D, de 10 a 18 unidades de antígeno D, de 11 a 17 unidades de antígeno D, de 12 a 16 unidades de antígeno D, o de 13 a 15 unidades de antígeno D; por ejemplo de alrededor o exactamente 14 unidades de antígeno D. 6.- El método de las reivindicaciones 1 a 4, en donde la vacuna comprende adicionalmente el poliovirus inactivado tipo 3 en una cantidad de 8 a 20 unidades de antígeno D, de 9 a 19 unidades de antígeno D, de 10 a 18 unidades de antígeno D, de 11 a 17 unidades de antígeno D, de 12 a 16 unidades de antígeno D, o de 13 a 15 unidades de antígeno D por 0.5 mililitros; por ejemplo alrededor o exactamente 14 unidades de antígeno D por 0.5 mililitros. 7.- El método de la reivindicación 5 ó 6, en donde la vacuna comprende el poliovirus inactivado tipo 3 en una dosis mayor de 8 y menor de 20 unidades de antígeno D.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0617602.8A GB0617602D0 (en) | 2006-09-07 | 2006-09-07 | Vaccine |
GB0625593A GB0625593D0 (en) | 2006-12-21 | 2006-12-21 | Vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6160334A2 true CO6160334A2 (es) | 2010-05-20 |
Family
ID=38823705
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO09023294A CO6160334A2 (es) | 2006-09-07 | 2009-03-06 | Metodo para la elaboracion de una vacuna de conbinacion para proteger contra polio |
CO09023296A CO6160335A2 (es) | 2006-09-07 | 2009-03-06 | Vacuna |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO09023296A CO6160335A2 (es) | 2006-09-07 | 2009-03-06 | Vacuna |
Country Status (26)
Country | Link |
---|---|
US (3) | US8956625B2 (es) |
EP (3) | EP2066344B2 (es) |
JP (5) | JP5814507B2 (es) |
KR (2) | KR20090057423A (es) |
CN (2) | CN103585624A (es) |
AT (1) | ATE511398T1 (es) |
AU (2) | AU2007293672B2 (es) |
BR (2) | BRPI0716518B8 (es) |
CA (2) | CA2662051A1 (es) |
CO (2) | CO6160334A2 (es) |
CR (2) | CR10669A (es) |
CY (2) | CY1111680T1 (es) |
DK (2) | DK2097102T3 (es) |
EA (2) | EA016417B1 (es) |
ES (1) | ES2387582T3 (es) |
HK (1) | HK1129563A1 (es) |
HR (2) | HRP20110431T1 (es) |
IL (2) | IL197272A (es) |
MA (2) | MA30715B1 (es) |
MX (2) | MX2009002560A (es) |
NO (2) | NO20090865L (es) |
NZ (2) | NZ575272A (es) |
PL (2) | PL2066344T3 (es) |
PT (2) | PT2097102E (es) |
SI (2) | SI2066344T1 (es) |
WO (2) | WO2008028956A1 (es) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8431136B2 (en) * | 2005-06-27 | 2013-04-30 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
EP2066344B2 (en) * | 2006-09-07 | 2016-06-29 | GlaxoSmithKline Biologicals S.A. | Inactivated Poliovirus combination vaccine |
KR101617464B1 (ko) | 2006-09-29 | 2016-05-02 | 잇판사이단호진한다이비세이부쯔뵤우겐큐우카이 | Ipv―dpt 백신 |
GB0810894D0 (en) | 2008-06-13 | 2008-07-23 | Novartis Vaccines & Diagnostic | Conjugated saccharide |
PE20100365A1 (es) | 2008-10-24 | 2010-05-21 | Panacea Biotec Ltd | Novedosas vacunas de combinacion con tos ferina de celulas enteras y metodo para su elaboracion |
GB0822633D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
US8574589B2 (en) * | 2009-05-11 | 2013-11-05 | Novartis Ag | Antigen purification process for pertactin antigen |
MX2012002723A (es) | 2009-09-02 | 2012-04-11 | Novartis Ag | Composiciones inmunogenicas que incluyen moduladores de la actividad de receptores tipo toll. |
AU2011258156B2 (en) * | 2010-05-26 | 2016-11-24 | Selecta Biosciences, Inc. | Multivalent synthetic nanocarrier vaccines |
WO2011148382A1 (en) | 2010-05-28 | 2011-12-01 | Biological E Limited | An improved process for the purification of capsular polysaccharides of haemophilus influenza - b, neisseria meningitis such as serotypes a, c, y and w-135, and other similar related capsular polysaccharides produced from both gram negative and gram positive microorganisms using aluminium phosphate with alcohol. |
ES2458355T3 (es) | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
RU2013144207A (ru) | 2011-03-02 | 2015-04-10 | Новартис Аг | Комбинированные вакцины с пониженными дозами антигена и/или адъюванта |
GB201105981D0 (en) * | 2011-04-08 | 2011-05-18 | Glaxosmithkline Biolog Sa | Novel process |
EP2771296B1 (en) | 2011-10-25 | 2017-09-27 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
DE102011122891B4 (de) | 2011-11-11 | 2014-12-24 | Novartis Ag | Fermentationsmedium, das frei von tierischen Bestandteilen ist, zur Herstellung von Diphtherie-Toxoiden zur Verwendung bei der Impfung von Menschen |
DE102011118371B4 (de) | 2011-11-11 | 2014-02-13 | Novartis Ag | Zur Impfung von Menschen geeignete Zusammensetzung, die ein Diphtherie-Toxoid umfasst, sowie Verfahren zu deren Herstellung |
GB2495341B (en) | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
EP2592137A1 (en) | 2011-11-11 | 2013-05-15 | Novartis AG | Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use |
RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
EP2822584A1 (en) | 2012-03-08 | 2015-01-14 | Novartis AG | Combination vaccines with tlr4 agonists |
CA2882619A1 (en) * | 2012-09-06 | 2014-03-13 | Novartis Ag | Combination vaccines with serogroup b meningococcus and d/t/p |
CN104717977A (zh) | 2012-10-03 | 2015-06-17 | 诺华股份有限公司 | 免疫原性组合物 |
AU2013328548A1 (en) | 2012-10-12 | 2015-05-07 | Glaxosmithkline Biologicals Sa | Non-cross-linked acellular pertussis antigens for use in combination vaccines |
KR20140060053A (ko) * | 2012-11-09 | 2014-05-19 | 아이진 주식회사 | 인플루엔자 백신용 면역증강제 |
EA030749B1 (ru) | 2013-03-08 | 2018-09-28 | Янссен Вэксинс Энд Превеншн Б.В. | Бесклеточная противококлюшная вакцина |
US9717649B2 (en) | 2013-04-24 | 2017-08-01 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9700486B2 (en) | 2013-04-24 | 2017-07-11 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9713572B2 (en) | 2013-04-24 | 2017-07-25 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9849066B2 (en) * | 2013-04-24 | 2017-12-26 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9603775B2 (en) | 2013-04-24 | 2017-03-28 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9700485B2 (en) | 2013-04-24 | 2017-07-11 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9707153B2 (en) | 2013-04-24 | 2017-07-18 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9707155B2 (en) | 2013-04-24 | 2017-07-18 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
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2009
- 2009-02-25 NO NO20090865A patent/NO20090865L/no not_active Application Discontinuation
- 2009-02-26 IL IL197272A patent/IL197272A/en not_active IP Right Cessation
- 2009-02-26 IL IL197310A patent/IL197310A/en not_active IP Right Cessation
- 2009-02-26 NO NO20090897A patent/NO20090897L/no not_active Application Discontinuation
- 2009-03-06 CO CO09023294A patent/CO6160334A2/es unknown
- 2009-03-06 CO CO09023296A patent/CO6160335A2/es unknown
- 2009-03-18 MA MA31725A patent/MA30715B1/fr unknown
- 2009-03-18 CR CR10669A patent/CR10669A/es not_active Application Discontinuation
- 2009-03-18 MA MA31726A patent/MA30716B1/fr unknown
- 2009-03-19 CR CR10672A patent/CR10672A/es not_active Application Discontinuation
- 2009-07-24 HK HK09106864.1A patent/HK1129563A1/xx not_active IP Right Cessation
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2011
- 2011-06-09 HR HR20110431T patent/HRP20110431T1/hr unknown
- 2011-06-28 CY CY20111100621T patent/CY1111680T1/el unknown
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2012
- 2012-07-06 HR HRP20120557TT patent/HRP20120557T1/hr unknown
- 2012-08-03 CY CY20121100696T patent/CY1113419T1/el unknown
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2013
- 2013-07-18 JP JP2013149549A patent/JP2013256505A/ja active Pending
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2014
- 2014-09-08 JP JP2014182142A patent/JP2015028041A/ja active Pending
- 2014-12-22 US US14/579,353 patent/US20150273047A1/en not_active Abandoned
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2015
- 2015-08-10 JP JP2015158139A patent/JP2016020361A/ja active Pending
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