PE20151588A1 - Vacuna contra el virus del dengue - Google Patents
Vacuna contra el virus del dengueInfo
- Publication number
- PE20151588A1 PE20151588A1 PE2015001630A PE2015001630A PE20151588A1 PE 20151588 A1 PE20151588 A1 PE 20151588A1 PE 2015001630 A PE2015001630 A PE 2015001630A PE 2015001630 A PE2015001630 A PE 2015001630A PE 20151588 A1 PE20151588 A1 PE 20151588A1
- Authority
- PE
- Peru
- Prior art keywords
- dengue virus
- against dengue
- vaccine against
- immune response
- adjuvant
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
La presente descripcion se refiere a composiciones inmunogenicas que inducen una respuesta inmune contra el virus del dengue. Mas especificamente, se refiere a vacunas del virus del dengue inactivado que incluyen un adyuvante. Las composiciones descritas en la presente memoria incluyen un adyuvante sin aluminio capaz de promover una respuesta inmune Th1. Tambien se describen metodos para su uso, por ejemplo, en la formulacion de medicamentos para la prevencion o el tratamiento de enfermedades producidas por el virus del dengue
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15306009P | 2009-02-17 | 2009-02-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20151588A1 true PE20151588A1 (es) | 2015-11-18 |
Family
ID=42174405
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2015001630A PE20151588A1 (es) | 2009-02-17 | 2010-02-16 | Vacuna contra el virus del dengue |
PE2011001431A PE20110992A1 (es) | 2009-02-17 | 2010-02-16 | Composicion inmunogenica que comprende un antigeno del virus del dengue |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2011001431A PE20110992A1 (es) | 2009-02-17 | 2010-02-16 | Composicion inmunogenica que comprende un antigeno del virus del dengue |
Country Status (23)
Country | Link |
---|---|
US (2) | US9265821B2 (es) |
EP (1) | EP2398821B1 (es) |
JP (2) | JP6058266B2 (es) |
KR (1) | KR101738704B1 (es) |
CN (1) | CN102395600B (es) |
AR (1) | AR075437A1 (es) |
AU (1) | AU2010215595A1 (es) |
BR (1) | BRPI1011224A2 (es) |
CA (1) | CA2752809A1 (es) |
CL (1) | CL2011001993A1 (es) |
CO (1) | CO6551750A2 (es) |
DO (1) | DOP2011000268A (es) |
ES (1) | ES2649020T3 (es) |
IL (1) | IL214385A (es) |
MX (1) | MX338898B (es) |
NZ (1) | NZ700477A (es) |
PE (2) | PE20151588A1 (es) |
PH (1) | PH12015501637A1 (es) |
SG (2) | SG173194A1 (es) |
TW (2) | TWI528972B (es) |
UY (1) | UY32457A (es) |
WO (1) | WO2010094663A1 (es) |
ZA (1) | ZA201105656B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
ES2458355T3 (es) | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
BR112013022397A2 (pt) * | 2011-03-02 | 2017-09-26 | Derek OHagan | vacinas combinadas com doses menores de antígeno e/ou adjuvante |
KR20140033171A (ko) * | 2011-05-26 | 2014-03-17 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 비활성화된 뎅기 바이러스 백신 |
JP6345603B2 (ja) | 2012-03-08 | 2018-06-20 | ノバルティス アーゲー | 追加免疫ワクチンのアジュバント化された処方物 |
BE1024160B9 (fr) | 2015-12-22 | 2017-12-06 | Glaxosmithkline Biologicals Sa | Formulation immunogène |
CA3022603A1 (en) * | 2016-05-10 | 2017-11-16 | Najit Technologies, Inc. | Inactivating pathogens and producing highly immunogenic inactivated vaccines using a dual oxidation process |
MX2018013640A (es) * | 2016-05-16 | 2019-08-01 | Infectious Disease Res Inst | Liposomas pegiladas y metodos de uso. |
CA3045563C (en) | 2016-12-23 | 2022-05-03 | Intervet International B.V. | Combination vaccine for swine |
CN111315406A (zh) * | 2017-09-08 | 2020-06-19 | 传染病研究所 | 包括皂苷的脂质体调配物及其使用方法 |
CN112601815A (zh) * | 2018-08-27 | 2021-04-02 | 迈凯恩技术有限公司 | 使用永生化单核细胞和诱导细胞的抗感染药物、疫苗等的评价方法 |
CN111150849A (zh) * | 2020-04-02 | 2020-05-15 | 广州隽沐生物科技股份有限公司 | 一种组合物及其制备方法及其应用 |
CN114377122B (zh) * | 2022-01-18 | 2023-04-07 | 四川大学 | 一种基于四面体框架核酸的复合佐剂、mRNA疫苗及其制备方法和用途 |
WO2023147342A2 (en) * | 2022-01-25 | 2023-08-03 | Takeda Vaccines, Inc. | Large-scale flaviviral vaccine production and manufacture |
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US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
ES2109685T5 (es) | 1993-03-23 | 2005-09-01 | Smithkline Beecham Biologicals S.A. | Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado. |
EP0729473B1 (en) | 1993-11-17 | 2000-08-23 | OM Pharma | Glucosamine disaccharides, method for their preparation, pharmaceutical composition comprising same, and their use |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
US6254873B1 (en) * | 1995-04-17 | 2001-07-03 | The United States Of America As Represented By The Secretary Of The Army | Inactivated dengue virus vaccine |
UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
US6846489B1 (en) | 1995-04-25 | 2005-01-25 | Smithkline Beecham Biologicals S.A. | Vaccines containing a saponin and a sterol |
US6303347B1 (en) | 1997-05-08 | 2001-10-16 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
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SK18602000A3 (sk) | 1998-06-08 | 2001-07-10 | Sca Emballage France | Obal umožňujúci rýchle vyrovnanie |
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DE60041250D1 (de) | 1999-03-26 | 2009-02-12 | Us Army | Multivalenter dengue-virus impfstoff |
EP1165756A2 (en) | 1999-03-26 | 2002-01-02 | Walter Reed Army Institute of Research | Adaptation of virus to vertebrate cells |
HU229255B1 (en) * | 1999-04-19 | 2013-10-28 | Smithkline Beecham Biolog | Vaccines |
AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
DK1402075T3 (da) | 2001-05-22 | 2013-02-11 | Us Gov Nat Inst Health | Udvikling af egnede mutationer til svækkelse af dengue-vira samt kimære dengue-vira |
GB0304799D0 (en) | 2003-03-03 | 2003-04-09 | Glaxosmithkline Biolog Sa | Novel method |
WO2008039171A2 (en) | 2005-08-08 | 2008-04-03 | Oregon Health & Science University | Inactivating pathogens with hydrogen peroxide for vaccine production |
JP4828189B2 (ja) * | 2005-09-14 | 2011-11-30 | 雅美 森山 | 分泌型IgA及びIgG抗体誘導剤 |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
ES2397714T3 (es) | 2006-10-12 | 2013-03-08 | Glaxosmithkline Biologicals S.A. | Vacuna que comprende un adyuvante de emulsión de aceite en agua |
EP2294192A4 (en) * | 2008-06-09 | 2011-11-23 | Jolla Inst Allergy Immunolog | COMPOSITIONS AND METHODS OF TREATMENT AND VACCINATION AGAINST DENGUE VIRUS (DV) |
-
2010
- 2010-02-16 NZ NZ700477A patent/NZ700477A/en not_active IP Right Cessation
- 2010-02-16 WO PCT/EP2010/051882 patent/WO2010094663A1/en active Application Filing
- 2010-02-16 CA CA2752809A patent/CA2752809A1/en not_active Abandoned
- 2010-02-16 KR KR1020117021610A patent/KR101738704B1/ko active IP Right Grant
- 2010-02-16 AR ARP100100442A patent/AR075437A1/es unknown
- 2010-02-16 MX MX2011008649A patent/MX338898B/es active IP Right Grant
- 2010-02-16 PE PE2015001630A patent/PE20151588A1/es not_active Application Discontinuation
- 2010-02-16 CN CN201080016827.1A patent/CN102395600B/zh not_active Expired - Fee Related
- 2010-02-16 JP JP2011549593A patent/JP6058266B2/ja not_active Expired - Fee Related
- 2010-02-16 SG SG2011055068A patent/SG173194A1/en unknown
- 2010-02-16 PE PE2011001431A patent/PE20110992A1/es not_active Application Discontinuation
- 2010-02-16 SG SG2014014385A patent/SG2014014385A/en unknown
- 2010-02-16 BR BRPI1011224A patent/BRPI1011224A2/pt not_active IP Right Cessation
- 2010-02-16 US US13/148,741 patent/US9265821B2/en not_active Expired - Fee Related
- 2010-02-16 AU AU2010215595A patent/AU2010215595A1/en not_active Abandoned
- 2010-02-16 EP EP10709443.5A patent/EP2398821B1/en active Active
- 2010-02-16 ES ES10709443.5T patent/ES2649020T3/es active Active
- 2010-02-17 UY UY0001032457A patent/UY32457A/es not_active Application Discontinuation
- 2010-02-22 TW TW099104980A patent/TWI528972B/zh active
- 2010-02-22 TW TW103135137A patent/TW201517915A/zh unknown
-
2011
- 2011-08-01 IL IL214385A patent/IL214385A/en not_active IP Right Cessation
- 2011-08-01 ZA ZA2011/05656A patent/ZA201105656B/en unknown
- 2011-08-16 CL CL2011001993A patent/CL2011001993A1/es unknown
- 2011-08-19 DO DO2011000268A patent/DOP2011000268A/es unknown
- 2011-08-30 CO CO11111072A patent/CO6551750A2/es not_active Application Discontinuation
-
2015
- 2015-06-22 JP JP2015125077A patent/JP6104988B2/ja not_active Expired - Fee Related
- 2015-07-23 PH PH12015501637A patent/PH12015501637A1/en unknown
-
2016
- 2016-01-11 US US14/992,354 patent/US20160120972A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |