CO5570667A2 - Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades - Google Patents

Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades

Info

Publication number
CO5570667A2
CO5570667A2 CO04030193A CO04030193A CO5570667A2 CO 5570667 A2 CO5570667 A2 CO 5570667A2 CO 04030193 A CO04030193 A CO 04030193A CO 04030193 A CO04030193 A CO 04030193A CO 5570667 A2 CO5570667 A2 CO 5570667A2
Authority
CO
Colombia
Prior art keywords
compounds
substituted substitute
heteroarilo
diseases
treatment
Prior art date
Application number
CO04030193A
Other languages
English (en)
Inventor
Brad Acker Alan
Vincent Edward Groppi Jr
Eric Jon Jacobsen
Piotr Karpinski
Charles Reiz Stevn
Original Assignee
Oharmacia And Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oharmacia And Upjohn Company filed Critical Oharmacia And Upjohn Company
Publication of CO5570667A2 publication Critical patent/CO5570667A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

1.- La invención proporciona compuestos de fórmula I: en la que azabiciclo esW esEstos compuestos pueden estar en forma de sales o composiciones farmacéuticas, mezclas racémicas o enantiómeros puros de los mismos. Los compuestos de fórmula I son útiles en productos farmacéuticos en los que es sabido que está implicado a7.
CO04030193A 2001-10-02 2004-03-30 Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades CO5570667A2 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32662901P 2001-10-02 2001-10-02
US32656501P 2001-10-02 2001-10-02
US33488601P 2001-11-15 2001-11-15
US33963301P 2001-12-12 2001-12-12

Publications (1)

Publication Number Publication Date
CO5570667A2 true CO5570667A2 (es) 2005-10-31

Family

ID=27502335

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04030193A CO5570667A2 (es) 2001-10-02 2004-03-30 Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades

Country Status (31)

Country Link
US (3) US6911543B2 (es)
EP (1) EP1432707B1 (es)
JP (1) JP4371811B2 (es)
KR (1) KR100614900B1 (es)
AP (1) AP1635A (es)
AR (1) AR037740A1 (es)
AT (1) ATE551340T1 (es)
BG (1) BG108650A (es)
BR (1) BR0213612A (es)
CA (1) CA2462453C (es)
CO (1) CO5570667A2 (es)
CZ (1) CZ2004408A3 (es)
DK (1) DK1432707T3 (es)
EA (1) EA007429B1 (es)
ES (1) ES2383001T3 (es)
GE (1) GEP20063814B (es)
HR (1) HRP20040259A2 (es)
HU (1) HUP0402289A2 (es)
IL (1) IL160884A0 (es)
IS (1) IS7188A (es)
MA (1) MA27138A1 (es)
MX (1) MXPA04003007A (es)
MY (1) MY138252A (es)
NO (1) NO20041368L (es)
NZ (1) NZ531786A (es)
OA (1) OA12708A (es)
PL (1) PL369895A1 (es)
RS (1) RS28004A (es)
SK (1) SK1562004A3 (es)
TN (1) TNSN04052A1 (es)
WO (1) WO2003029252A1 (es)

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US20050222196A1 (en) 2005-10-06
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NZ531786A (en) 2006-10-27
PL369895A1 (en) 2005-05-02
JP4371811B2 (ja) 2009-11-25
OA12708A (en) 2006-06-26
NO20041368L (no) 2004-06-01
AR037740A1 (es) 2004-12-01
IS7188A (is) 2004-03-18
EP1432707A1 (en) 2004-06-30
AP1635A (en) 2006-07-14
CA2462453C (en) 2009-07-28
KR20040045466A (ko) 2004-06-01
WO2003029252A1 (en) 2003-04-10
HRP20040259A2 (en) 2004-08-31
MA27138A1 (fr) 2005-01-03
ATE551340T1 (de) 2012-04-15
MY138252A (en) 2009-05-29
CA2462453A1 (en) 2003-04-10
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US20050234092A1 (en) 2005-10-20
US6911543B2 (en) 2005-06-28
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KR100614900B1 (ko) 2006-08-25
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US20030153595A1 (en) 2003-08-14

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