NO20052884L - Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. - Google Patents

Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Info

Publication number
NO20052884L
NO20052884L NO20052884A NO20052884A NO20052884L NO 20052884 L NO20052884 L NO 20052884L NO 20052884 A NO20052884 A NO 20052884A NO 20052884 A NO20052884 A NO 20052884A NO 20052884 L NO20052884 L NO 20052884L
Authority
NO
Norway
Prior art keywords
indolpyridine
substituted
compounds
infective agents
infective
Prior art date
Application number
NO20052884A
Other languages
English (en)
Other versions
NO20052884D0 (no
Inventor
Piet Tom Bert Paul Wigerinck
Dominique Louis Nest Surleraux
Bart Rudolf Romanie Kesteleyn
Dirk Edward Desire Jochmans
Abdellah Tahri
Wim Van De Vreken
Natalie Maria Franc Kindermans
Maxime Francis Jean-Mar Canard
Kurt Hertogs
Eva Bettens
Veronique Corine Paul De Vroey
Jing Wang
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of NO20052884D0 publication Critical patent/NO20052884D0/no
Publication of NO20052884L publication Critical patent/NO20052884L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Abstract

2005 -07- 2 9 Sammendrag 0. nr. E40674 Foreliggende oppfinnelse angår nye pyridazinonderivater.
NO20052884A 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. NO20052884L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02079783 2002-11-15
US43495002P 2002-12-20 2002-12-20
PCT/EP2003/050837 WO2004046143A1 (en) 2002-11-15 2003-11-14 Substituted indolepyridinium as anti-infective compounds

Publications (2)

Publication Number Publication Date
NO20052884D0 NO20052884D0 (no) 2005-06-14
NO20052884L true NO20052884L (no) 2005-08-15

Family

ID=32327852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052884A NO20052884L (no) 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Country Status (16)

Country Link
US (2) US7608726B2 (no)
EP (1) EP1594870B1 (no)
JP (1) JP2006508145A (no)
KR (1) KR20050084621A (no)
CN (1) CN100457754C (no)
AP (1) AP1927A (no)
AU (1) AU2003296760B2 (no)
BR (1) BR0316209A (no)
CA (1) CA2506316A1 (no)
EA (1) EA009871B1 (no)
HR (1) HRP20050543A2 (no)
MX (1) MXPA05005146A (no)
NO (1) NO20052884L (no)
NZ (1) NZ540321A (no)
PL (1) PL376683A1 (no)
WO (1) WO2004046143A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
ES2351702T3 (es) * 2004-05-17 2011-02-09 Tibotec Pharmaceuticals 1-fenil-1,5-dihidro-pirido[3,2-b]indol-2-onas 6,7,8,9-sustituidas útiles como agentes farmacéuticos antiinfecciosos.
EA200602136A1 (ru) * 2004-05-17 2007-04-27 Тиботек Фармасьютикалз Лтд. Комбинации замещенных 1-фенил-1,5-дигидропиридо[3,2-b] индол-2-онов и других ингибиторов вич
TW200613307A (en) * 2004-05-17 2006-05-01 Tibotec Pharm Ltd 4-substituted-1,5-dihydro-pyrido[3,2-b]indol-2-ones
CN1953978B (zh) * 2004-05-17 2010-09-29 泰博特克药品有限公司 作为抗病毒剂的5-取代的1-苯基-1,5-二氢-吡啶并[3,2-b]吲哚-2-酮及其类似物
AR049340A1 (es) * 2004-05-17 2006-07-19 Tibotec Pharm Ltd 1- heterociclil - l, 5- dihidro- pirido (3,2-b) indol - 2- onas
TW200626574A (en) 2004-09-30 2006-08-01 Tibotec Pharm Ltd HIV inhibiting 5-heterocyclyl pyrimidines
CN101027288B (zh) 2004-09-30 2013-04-17 泰博特克药品有限公司 抑制hiv的5-取代嘧啶
AR056918A1 (es) * 2005-01-10 2007-11-07 Tibotec Pharm Ltd 2-oxo-3-ciano-1,6a-diaza-tetrahidro-fluorantenos 1,5,6-sustituidos, proceso de preparacion del compuesto y composicion farmaceutica
EP1853720A1 (en) * 2005-02-04 2007-11-14 Tibotec Pharmaceuticals Ltd. Screening method for competitive hiv rt inhibitors
WO2007088214A2 (en) * 2006-02-03 2007-08-09 Tibotec Pharmaceuticals Ltd. Treating hiv infection, wherein hiv has a k65r mutation
EP2004632B1 (en) 2006-03-30 2014-03-12 Janssen R&D Ireland Hiv inhibiting 5-amido substituted pyrimidines
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
CA2674178C (en) 2006-12-29 2015-11-10 Tibotec Pharmaceuticals Ltd. Hiv inhibiting 6-substituted pyrimidines
AU2007341228B2 (en) 2006-12-29 2013-04-18 Janssen Sciences Ireland Uc HIV inhibiting 5,6-substituted pyrimidines
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
DK2175857T3 (da) 2007-07-12 2013-12-02 Janssen R & D Ireland Krystallinsk form af (e) 4-[[4-[[4-(2-cyanoethenyl)-2.6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitril
CN102361867A (zh) 2009-01-23 2012-02-22 百时美施贵宝公司 在治疗自身免疫疾病和炎性疾病中作为s1p激动剂的取代的噁二唑衍生物
US8404672B2 (en) 2009-01-23 2013-03-26 Bristol-Meyers Squibb Company Substituted heterocyclic compounds
US8389509B2 (en) 2009-01-23 2013-03-05 Bristol-Myers Squibb Company Substituted pyrazole compounds
JP5643290B2 (ja) 2009-04-09 2014-12-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｈｉｖ複製の阻害薬
EA201201548A1 (ru) * 2010-05-14 2013-05-30 Эффектис Фармасьютиклз Аг Новые способы получения p2x7r антагонистов
WO2012014760A1 (ja) 2010-07-28 2012-02-02 住友化学株式会社 カルボン酸アミドの製造方法
UA115576C2 (uk) 2012-12-06 2017-11-27 Байєр Фарма Акцієнгезелльшафт Похідні бензимідазолу як антагоністи ер4
US10640497B2 (en) * 2015-12-02 2020-05-05 Syngenta Participations Ag Microbiocidal oxadiazole derivatives
US11066396B2 (en) * 2016-06-23 2021-07-20 Merck Sharp & Dohme Corp. 3-aryl- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histonedeacetylase 6 (HDAC6) inhibitors
KR200486209Y1 (ko) 2016-07-05 2018-04-16 박우 편육 가공기구
CN108299428B (zh) * 2018-04-04 2019-09-27 山东大学 8-胺基-7-甲酸甲酯-吡嗪骈吡啶酮衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059123A2 (en) * 2000-12-18 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
US20020182151A1 (en) * 2000-12-18 2002-12-05 The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Services Benzoylalkylindolepyridinium componds and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
PL376683A1 (pl) 2006-01-09
BR0316209A (pt) 2005-09-27
US20060173000A1 (en) 2006-08-03
EA009871B1 (ru) 2008-04-28
JP2006508145A (ja) 2006-03-09
US7608726B2 (en) 2009-10-27
EA200500822A1 (ru) 2005-12-29
AP1927A (en) 2008-12-10
CN1738816A (zh) 2006-02-22
KR20050084621A (ko) 2005-08-26
AP2005003334A0 (en) 2005-06-30
EP1594870A1 (en) 2005-11-16
WO2004046143A1 (en) 2004-06-03
NZ540321A (en) 2007-09-28
CA2506316A1 (en) 2004-06-03
NO20052884D0 (no) 2005-06-14
US20100048563A1 (en) 2010-02-25
CN100457754C (zh) 2009-02-04
AU2003296760A1 (en) 2004-06-15
EP1594870B1 (en) 2011-05-11
MXPA05005146A (es) 2005-07-22
AU2003296760B2 (en) 2009-11-19
HRP20050543A2 (en) 2006-09-30

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