NO20052884L - Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. - Google Patents

Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Info

Publication number
NO20052884L
NO20052884L NO20052884A NO20052884A NO20052884L NO 20052884 L NO20052884 L NO 20052884L NO 20052884 A NO20052884 A NO 20052884A NO 20052884 A NO20052884 A NO 20052884A NO 20052884 L NO20052884 L NO 20052884L
Authority
NO
Norway
Prior art keywords
indolpyridine
substituted
compounds
infective agents
infective
Prior art date
Application number
NO20052884A
Other languages
English (en)
Other versions
NO20052884D0 (no
Inventor
Piet Tom Bert Paul Wigerinck
Dominique Louis Nest Surleraux
Bart Rudolf Romanie Kesteleyn
Dirk Edward Desire Jochmans
Abdellah Tahri
Wim Van De Vreken
Natalie Maria Franc Kindermans
Maxime Francis Jean-Mar Canard
Kurt Hertogs
Eva Bettens
Veronique Corine Paul De Vroey
Jing Wang
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of NO20052884D0 publication Critical patent/NO20052884D0/no
Publication of NO20052884L publication Critical patent/NO20052884L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

2005 -07- 2 9 Sammendrag 0. nr. E40674 Foreliggende oppfinnelse angår nye pyridazinonderivater.
NO20052884A 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler. NO20052884L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02079783 2002-11-15
US43495002P 2002-12-20 2002-12-20
PCT/EP2003/050837 WO2004046143A1 (en) 2002-11-15 2003-11-14 Substituted indolepyridinium as anti-infective compounds

Publications (2)

Publication Number Publication Date
NO20052884D0 NO20052884D0 (no) 2005-06-14
NO20052884L true NO20052884L (no) 2005-08-15

Family

ID=32327852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052884A NO20052884L (no) 2002-11-15 2005-06-14 Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.

Country Status (16)

Country Link
US (2) US7608726B2 (no)
EP (1) EP1594870B1 (no)
JP (1) JP2006508145A (no)
KR (1) KR20050084621A (no)
CN (1) CN100457754C (no)
AP (1) AP1927A (no)
AU (1) AU2003296760B2 (no)
BR (1) BR0316209A (no)
CA (1) CA2506316A1 (no)
EA (1) EA009871B1 (no)
HR (1) HRP20050543A2 (no)
MX (1) MXPA05005146A (no)
NO (1) NO20052884L (no)
NZ (1) NZ540321A (no)
PL (1) PL376683A1 (no)
WO (1) WO2004046143A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
RU2362776C2 (ru) * 2004-05-17 2009-07-27 Тиботек Фармасьютикалз Лтд. 5-ЗАМЕЩЕННЫЕ 1-ФЕНИЛ-1,5-ДИГИДРОПИРИДО[3,2-b]ИНДОЛ-2-ОНЫ И АНАЛОГИ КАК ПРОТИВОВИРУСНЫЕ ПРЕПАРАТЫ
AR049340A1 (es) 2004-05-17 2006-07-19 Tibotec Pharm Ltd 1- heterociclil - l, 5- dihidro- pirido (3,2-b) indol - 2- onas
MXPA06013316A (es) * 2004-05-17 2007-02-02 Tibotec Pharm Ltd Combinaciones de 1-fenil-1,5-dihidro-pirido-[3,2-b]indol-2-onas sustituidas y otros inhibidores de virus de inmunodeficiencia humana.
DE602005023600D1 (de) 2004-05-17 2010-10-28 Little Island Co Cork Substituierte 1-phenyl-1,5-dihydro-pyridoä3,2-büindol-2-on-derivate verwendbar als pharmazeutische antiinfektiva
TW200613307A (en) 2004-05-17 2006-05-01 Tibotec Pharm Ltd 4-substituted-1,5-dihydro-pyrido[3,2-b]indol-2-ones
ES2380631T3 (es) 2004-09-30 2012-05-17 Tibotec Pharmaceuticals Pirimidinas sustituidas en posición 5 inhibidoras de VIH
BRPI0516746A (pt) 2004-09-30 2008-09-23 Tibotec Pharm Ltd 5-heterociclil pirimidinas para inibição de hiv
AR056918A1 (es) * 2005-01-10 2007-11-07 Tibotec Pharm Ltd 2-oxo-3-ciano-1,6a-diaza-tetrahidro-fluorantenos 1,5,6-sustituidos, proceso de preparacion del compuesto y composicion farmaceutica
JP2008528047A (ja) * 2005-02-04 2008-07-31 テイボテク・フアーマシユーチカルズ・リミテツド 競合的ｈｉｖのｒｔインヒビターのスクリーニング法
JP2009525310A (ja) * 2006-02-03 2009-07-09 テイボテク・フアーマシユーチカルズ・リミテツド 突然変異したｈｉｖを処置する方法
ES2465666T3 (es) 2006-03-30 2014-06-06 Janssen R&D Ireland Pirimidinas 5-amido-sustituidas inhibidoras del HIV
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
BRPI0720858B8 (pt) 2006-12-29 2021-05-25 Janssen R & D Ireland pirimidinas 6-substituídas inibidoras de hiv e composição farmacêutica que as compreende
ES2523863T3 (es) 2006-12-29 2014-12-02 Janssen R&D Ireland Pirimidinas 5,6-sustituidas inhibidoras del VIH
TWI494133B (zh) 2007-03-14 2015-08-01 Tibotec Pharm Ltd 重組用粉末
CA2693044C (en) 2007-07-12 2017-03-14 Tibotec Pharmaceuticals Crystalline form of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2 pyrimidinyl]amino]benzonitrile
JP2012515787A (ja) * 2009-01-23 2012-07-12 ブリストル−マイヤーズ スクイブ カンパニー 自己免疫疾患および炎症性疾患の処置におけるｓ１ｐアゴニストとしての置換オキサジアゾール誘導体
WO2010085582A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
WO2010085584A1 (en) 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Pyrazole-i, 2, 4 -oxad iazole derivatives as s.phing0sine-1-ph0sphate agonists
CA2758149A1 (en) 2009-04-09 2010-10-14 Boehringer Ingelheim International Gmbh Inhibitors of hiv replication
AU2011252351A1 (en) * 2010-05-14 2012-10-11 Affectis Pharmaceuticals Ag Novel methods for the preparation of P2X7R antagonists
EP2599769A4 (en) 2010-07-28 2015-05-20 Sumitomo Chemical Co PROCESS FOR PREPARING A CARBOXYLIC ACID AMID
UA115576C2 (uk) 2012-12-06 2017-11-27 Байєр Фарма Акцієнгезелльшафт Похідні бензимідазолу як антагоністи ер4
US10640497B2 (en) * 2015-12-02 2020-05-05 Syngenta Participations Ag Microbiocidal oxadiazole derivatives
US11066396B2 (en) * 2016-06-23 2021-07-20 Merck Sharp & Dohme Corp. 3-aryl- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histonedeacetylase 6 (HDAC6) inhibitors
KR200486209Y1 (ko) 2016-07-05 2018-04-16 박우 편육 가공기구
CN108299428B (zh) * 2018-04-04 2019-09-27 山东大学 8-胺基-7-甲酸甲酯-吡嗪骈吡啶酮衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059123A2 (en) * 2000-12-18 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
US20020182151A1 (en) * 2000-12-18 2002-12-05 The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Services Benzoylalkylindolepyridinium componds and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
AP2005003334A0 (en) 2005-06-30
US20100048563A1 (en) 2010-02-25
NO20052884D0 (no) 2005-06-14
AU2003296760B2 (en) 2009-11-19
CN1738816A (zh) 2006-02-22
US20060173000A1 (en) 2006-08-03
EP1594870A1 (en) 2005-11-16
US7608726B2 (en) 2009-10-27
PL376683A1 (pl) 2006-01-09
BR0316209A (pt) 2005-09-27
AP1927A (en) 2008-12-10
EP1594870B1 (en) 2011-05-11
MXPA05005146A (es) 2005-07-22
WO2004046143A1 (en) 2004-06-03
KR20050084621A (ko) 2005-08-26
NZ540321A (en) 2007-09-28
JP2006508145A (ja) 2006-03-09
CN100457754C (zh) 2009-02-04
HRP20050543A2 (en) 2006-09-30
CA2506316A1 (en) 2004-06-03
EA009871B1 (ru) 2008-04-28
AU2003296760A1 (en) 2004-06-15
EA200500822A1 (ru) 2005-12-29

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