CO5140096A1 - Vehiculo viscoso de una fase para la suspension de principios activos - Google Patents
Vehiculo viscoso de una fase para la suspension de principios activosInfo
- Publication number
- CO5140096A1 CO5140096A1 CO00007997A CO00007997A CO5140096A1 CO 5140096 A1 CO5140096 A1 CO 5140096A1 CO 00007997 A CO00007997 A CO 00007997A CO 00007997 A CO00007997 A CO 00007997A CO 5140096 A1 CO5140096 A1 CO 5140096A1
- Authority
- CO
- Colombia
- Prior art keywords
- vehicle
- aqueous
- stable
- viscose
- suspension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Un vehículo viscoso biocompatible estable de fase simple y no acuoso capaz de suspender agentes beneficiosos y de dispensar homogéneamente dicho agente beneficioso durante un período de tiempo extendido a temperatura del cuerpo y a velocidades de flujo bajas, en donde dicho vehículo tiene como componentes disolventes, tensoactivos y/o polímeros.1Una formulación de proteína viscosa no acuosa estable que comprendea) por lo menos un agente beneficioso, yb) un vehículo viscoso biocompatible no acuoso de fase simple, cuya formulación es capaz de dispensarse uniformemente durante un período de tiempo extendido y a una velocidad de flujo baja, en donde dicho vehículo tiene como componentes disolventes, tensoactivos y/o polímeros.<EMI FILE="00007997_1" ID="1" IMF=JPEG >
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11917099P | 1999-02-08 | 1999-02-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5140096A1 true CO5140096A1 (es) | 2002-03-22 |
Family
ID=22382917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00007997A CO5140096A1 (es) | 1999-02-08 | 2000-02-08 | Vehiculo viscoso de una fase para la suspension de principios activos |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1666026B2 (es) |
JP (1) | JP4861551B2 (es) |
KR (2) | KR100858856B1 (es) |
CN (1) | CN1232244C (es) |
AR (1) | AR029613A1 (es) |
AT (2) | ATE322889T1 (es) |
AU (1) | AU775904B2 (es) |
CA (1) | CA2361424C (es) |
CO (1) | CO5140096A1 (es) |
CY (1) | CY1119950T1 (es) |
DE (1) | DE60027272T2 (es) |
DK (1) | DK1666026T4 (es) |
ES (2) | ES2261190T3 (es) |
HK (2) | HK1041451B (es) |
HU (1) | HUP0200202A3 (es) |
IL (1) | IL144755A0 (es) |
NO (1) | NO20013861L (es) |
NZ (1) | NZ513441A (es) |
PT (2) | PT1152749E (es) |
TW (2) | TWI292716B (es) |
WO (1) | WO2000045790A2 (es) |
ZA (1) | ZA200106443B (es) |
Families Citing this family (49)
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JP4931282B2 (ja) * | 2000-10-02 | 2012-05-16 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
US7731947B2 (en) * | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
KR20050088196A (ko) * | 2002-12-19 | 2005-09-02 | 알자 코포레이션 | 안정한 비수성 단일 상 겔 및 이식가능한 장치로부터전달하기 위한 이의 제형 |
AU2004227985B2 (en) | 2003-03-31 | 2009-04-02 | Intarcia Therapeutics, Inc. | Osmotic pump with means for dissipating internal pressure |
DE602004015755D1 (de) * | 2003-03-31 | 2008-09-25 | Alza Corp | Nicht wässrige einphasige visköse vehikel und formulierungen die diese vehikel verwenden |
US20050118206A1 (en) * | 2003-11-14 | 2005-06-02 | Luk Andrew S. | Surfactant-based gel as an injectable, sustained drug delivery vehicle |
US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
US20060141040A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
US20060263433A1 (en) * | 2005-02-03 | 2006-11-23 | Ayer Rupal A | Suspension formulation of interferon |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
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ES2398126T3 (es) | 2006-08-09 | 2013-03-13 | Intarcia Therapeutics, Inc | Sistemas de liberación osmótica y unidades de pistón |
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CA2691531C (en) | 2007-06-22 | 2016-11-01 | Board Of Regents,The University Of Texas System | Formation of stable submicron peptide or protein particles by thin film freezing |
DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
EP2376522A4 (en) | 2008-11-16 | 2013-12-25 | Univ Texas | LOW VISCOSIS HIGHLY CONCENTRATED SUSPENSIONS |
NZ747990A (en) | 2009-09-28 | 2020-06-26 | Intarcia Therapeutics Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
DK2547323T3 (en) | 2010-03-17 | 2016-05-02 | Novaliq Gmbh | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INCREASED INTRAOCULAR PRESSURE |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
ES2962524T3 (es) | 2011-05-25 | 2024-03-19 | Dermaliq Therapeutics Inc | Composición farmacéutica tópica a base de alcanos semifluorados |
DK2714008T3 (en) | 2011-05-25 | 2017-03-13 | Novaliq Gmbh | PHARMACEUTICAL COMPOSITION FOR APPLICATION ON NAIL |
WO2013063284A1 (en) | 2011-10-25 | 2013-05-02 | Onclave Therapeutics | Antibody formulations and methods |
EP2806886B1 (en) | 2012-01-23 | 2017-03-01 | Novaliq GmbH | Stabilised protein compositions based on semifluorinated alkanes |
CN113679697A (zh) | 2012-09-12 | 2021-11-23 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
EP2895144B1 (en) | 2012-09-12 | 2017-01-11 | Novaliq GmbH | Semifluorinated alkane compositions |
WO2015011199A1 (en) | 2013-07-23 | 2015-01-29 | Novaliq Gmbh | Stabilized antibody compositions |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
NZ738102A (en) | 2015-06-03 | 2024-02-23 | Intarcia Therapeutics Inc | Implant placement and removal systems |
US20170087100A1 (en) | 2015-09-30 | 2017-03-30 | Novaliq Gmbh | Semifluorinated compounds and their compositions |
PL3356313T3 (pl) | 2015-09-30 | 2020-11-16 | Novaliq Gmbh | 2-perfluoroheksylooktan do podawania okulistycznego |
TWI814219B (zh) | 2016-05-16 | 2023-09-01 | 美商因塔希亞治療公司 | 升糖素受體選擇性多肽和彼之使用方法 |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
KR102257916B1 (ko) | 2016-06-23 | 2021-05-28 | 노바리크 게엠베하 | 드롭 디스펜서를 포함하는 키트 |
ES2969758T3 (es) | 2016-09-22 | 2024-05-22 | Novaliq Gmbh | Composiciones farmacéuticas para usar en la terapia de la blefaritis |
JP6869336B2 (ja) | 2016-09-23 | 2021-05-12 | ノバリック ゲーエムベーハー | シクロスポリンを含む眼科用組成物 |
US10835580B2 (en) | 2017-01-03 | 2020-11-17 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
BR112019021917A8 (pt) | 2017-04-21 | 2023-03-21 | Novaliq Gmbh | Composições de iodo |
WO2018206656A1 (en) | 2017-05-12 | 2018-11-15 | Novaliq Gmbh | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
EP3687496A1 (en) | 2017-09-27 | 2020-08-05 | Novaliq GmbH | Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases |
US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
KR20200128407A (ko) | 2018-03-02 | 2020-11-12 | 노바리크 게엠베하 | 네비볼롤을 포함하는 약제학적 조성물 |
CA3111870C (en) | 2018-09-27 | 2022-04-12 | Novaliq Gmbh | Topical sunscreen formulation |
SG11202102820VA (en) | 2018-10-12 | 2021-04-29 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
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2000
- 2000-02-02 EP EP06075430.6A patent/EP1666026B2/en not_active Expired - Lifetime
- 2000-02-02 PT PT00913350T patent/PT1152749E/pt unknown
- 2000-02-02 HU HU0200202A patent/HUP0200202A3/hu unknown
- 2000-02-02 DK DK06075430T patent/DK1666026T4/da active
- 2000-02-02 AT AT00913350T patent/ATE322889T1/de not_active IP Right Cessation
- 2000-02-02 JP JP2000596910A patent/JP4861551B2/ja not_active Expired - Fee Related
- 2000-02-02 EP EP00913350A patent/EP1152749B1/en not_active Expired - Lifetime
- 2000-02-02 AT AT06075430T patent/ATE537811T1/de active
- 2000-02-02 NZ NZ513441A patent/NZ513441A/xx not_active IP Right Cessation
- 2000-02-02 CN CNB008035636A patent/CN1232244C/zh not_active Expired - Fee Related
- 2000-02-02 KR KR1020017010037A patent/KR100858856B1/ko active IP Right Grant
- 2000-02-02 KR KR1020087011434A patent/KR20080045300A/ko not_active Application Discontinuation
- 2000-02-02 DE DE60027272T patent/DE60027272T2/de not_active Expired - Lifetime
- 2000-02-02 ES ES00913350T patent/ES2261190T3/es not_active Expired - Lifetime
- 2000-02-02 WO PCT/US2000/002772 patent/WO2000045790A2/en active IP Right Grant
- 2000-02-02 PT PT06075430T patent/PT1666026E/pt unknown
- 2000-02-02 CA CA002361424A patent/CA2361424C/en not_active Expired - Fee Related
- 2000-02-02 IL IL14475500A patent/IL144755A0/xx not_active IP Right Cessation
- 2000-02-02 AU AU34816/00A patent/AU775904B2/en not_active Ceased
- 2000-02-02 ES ES06075430.6T patent/ES2379471T5/es not_active Expired - Lifetime
- 2000-02-03 TW TW089101904A patent/TWI292716B/zh active
- 2000-02-03 TW TW096109155A patent/TW200730199A/zh unknown
- 2000-02-07 AR ARP000100524A patent/AR029613A1/es not_active Application Discontinuation
- 2000-02-08 CO CO00007997A patent/CO5140096A1/es unknown
-
2001
- 2001-08-06 ZA ZA200106443A patent/ZA200106443B/xx unknown
- 2001-08-08 NO NO20013861A patent/NO20013861L/no not_active Application Discontinuation
-
2002
- 2002-04-30 HK HK02103234.8A patent/HK1041451B/zh not_active IP Right Cessation
-
2006
- 2006-12-06 HK HK06113414.5A patent/HK1094528A1/xx not_active IP Right Cessation
-
2015
- 2015-05-22 CY CY20121100281T patent/CY1119950T1/el unknown
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