CO4960646A1 - Tabletas de metilcelulosa rapidamente desintegrables - Google Patents

Tabletas de metilcelulosa rapidamente desintegrables

Info

Publication number
CO4960646A1
CO4960646A1 CO98047415A CO98047415A CO4960646A1 CO 4960646 A1 CO4960646 A1 CO 4960646A1 CO 98047415 A CO98047415 A CO 98047415A CO 98047415 A CO98047415 A CO 98047415A CO 4960646 A1 CO4960646 A1 CO 4960646A1
Authority
CO
Colombia
Prior art keywords
tablet
tablet according
agent
starch
methyl cellulose
Prior art date
Application number
CO98047415A
Other languages
English (en)
Spanish (es)
Inventor
Bruce Daggy
I Metha Naresh
Nayak Priyashri
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of CO4960646A1 publication Critical patent/CO4960646A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CO98047415A 1997-08-22 1998-08-19 Tabletas de metilcelulosa rapidamente desintegrables CO4960646A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5689997P 1997-08-22 1997-08-22
US8164498P 1998-04-14 1998-04-14

Publications (1)

Publication Number Publication Date
CO4960646A1 true CO4960646A1 (es) 2000-09-25

Family

ID=26735830

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98047415A CO4960646A1 (es) 1997-08-22 1998-08-19 Tabletas de metilcelulosa rapidamente desintegrables

Country Status (18)

Country Link
US (2) US6372253B1 (https=)
EP (1) EP1014949A4 (https=)
JP (1) JP2001513546A (https=)
KR (1) KR20010023198A (https=)
CN (1) CN1240374C (https=)
AR (3) AR016827A1 (https=)
AU (1) AU745682B2 (https=)
BR (1) BR9811987A (https=)
CA (1) CA2301132C (https=)
CO (1) CO4960646A1 (https=)
EA (1) EA003663B1 (https=)
HU (1) HUP0003186A3 (https=)
MY (1) MY137768A (https=)
NZ (1) NZ502890A (https=)
PL (1) PL338786A1 (https=)
TW (1) TWI228421B (https=)
UA (1) UA70926C2 (https=)
WO (1) WO1999009959A1 (https=)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US6348264B1 (en) 1998-04-27 2002-02-19 Roquette Freres Process for producing low de starch hydrolysates by nanofiltration fractionation, products obtained thereby, and use of such products
WO2000013667A1 (en) 1998-09-08 2000-03-16 Smithkline Beecham Corporation Lipstatin derivative-soluble fiber tablets
ES2197064T3 (es) * 2000-10-24 2004-01-01 Fit Gmbh Granulado de agentes de desintegracion conjuntamente elaborados.
HU230253B1 (hu) * 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
JP4633469B2 (ja) 2002-12-16 2011-02-16 キッセイ薬品工業株式会社 経口固形医薬
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2005009395A2 (en) * 2003-07-23 2005-02-03 L. Perrigo Company Cellulosic fiber containing composition
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
CN1913876B (zh) * 2003-12-09 2013-06-26 大日本住友制药株式会社 含药物的颗粒和包含这种颗粒的固体制剂
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
ES2391030T3 (es) * 2005-03-23 2012-11-20 Bpsi Holdings, Llc. Composiciones de almidón aglomerado
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CN102813655A (zh) * 2005-05-05 2012-12-12 布里斯托尔-迈尔斯斯奎布公司 Src/abl抑制剂配方
CA2617051C (en) * 2005-07-29 2013-12-17 Stichting Groningen Centre For Drug Research Ph-controlled pulsatile delivery system, methods for preparation and use thereof
PE20070698A1 (es) * 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
IN2014DN03102A (https=) 2006-11-07 2015-07-10 Procter & Gamble
AR065096A1 (es) 2007-02-01 2009-05-13 Takeda Pharmaceutical Preparacion solida
US7767248B2 (en) * 2007-02-02 2010-08-03 Overly Iii Harry J Soft chew confectionary with high fiber and sugar content and method for making same
CA2689434C (en) * 2007-06-04 2017-09-26 Shear/Kershman Laboratories, Inc. Tamper resistant lipid-based oral dosage form for opioid agonists
US8420700B1 (en) * 2008-06-04 2013-04-16 James M. Bausch Tamper resistant lipid-based oral dosage form for sympathomimetic amines
DE102008037324A1 (de) * 2008-08-11 2010-02-18 Ratiopharm Gmbh Pharmazeutische Formulierung zur pulmonalen Blutdrucksenkung
KR20110097840A (ko) * 2008-11-17 2011-08-31 바스프 에스이 전분 함유 과립 제제
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
US20110212171A1 (en) * 2010-01-08 2011-09-01 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
TWI564008B (zh) 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 難溶性藥物之溶解性改善製劑
US9675551B2 (en) * 2011-10-25 2017-06-13 Expermed S.A. Sublingual pharmaceutical composition containing an antihistamine agent and method for the preparation thereof
PT2877163T (pt) 2012-07-27 2019-05-24 Redhill Biopharma Ltd Formulações e métodos de fabrico de formulações para utilização na evacuação colónica
MX392941B (es) * 2016-09-07 2025-03-24 Celgene Corp Composiciones para comprimidos.
US20230346695A1 (en) 2020-09-29 2023-11-02 Millicent Pharma Limited Orodispersible formulations

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3402240A (en) 1957-06-25 1968-09-17 Pfizer & Co C Medicinal tablet and process of making same
US3039922A (en) 1959-08-17 1962-06-19 Carter Prod Inc Method of administering tablets having decongestant and anti-histaminic activity
US3147187A (en) 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
US3622673A (en) 1968-11-14 1971-11-23 Upjohn Co 4-(1,4,5,6-TETRAHYDROZEPINO 4,5-b INDOL-3(2H)-YL-BUTYROPHENON COMPOSITIONS AND PROCESS OF TREATMENT MENTAL OR EMOTIONAL DISORDERS
DE1931910B2 (de) 1969-06-24 1974-11-28 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung fester, steuerbar resorbierbarer Arzneimittelzubereitungen schwer löslicher Wirkstoffe
US3961056A (en) 1974-02-11 1976-06-01 The Upjohn Company Substituted morpholine guanidines for the treatment of arrhythmic conditions
US3968211A (en) 1974-02-11 1976-07-06 The Upjohn Company Compositions and methods of use of amidines for anti-arrhythmic purposes
JPS5438167B2 (https=) * 1974-04-27 1979-11-19
US4048331A (en) 1974-10-15 1977-09-13 The Upjohn Company Process of treatment
US3969504A (en) 1975-02-14 1976-07-13 The Upjohn Co. 6-Phenyl benzodiazepine antidepressants
US4148879A (en) 1977-12-23 1979-04-10 Nelson Research & Development Company Inhibition of platelet aggregation with selected phosphonic and phosphinic acid esters
US4148878A (en) 1977-12-23 1979-04-10 Nelson Research & Development Company Inhibition of platelet aggregation with selected phosphoric acid esters
US4327080A (en) 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
JPS58144316A (ja) 1982-02-18 1983-08-27 Chiyoda Yakuhin Kk 安定なインドメタシン錠
US4508726A (en) 1982-09-16 1985-04-02 The Upjohn Company Treatment of panic disorders with alprazolam
ZA841044B (en) 1983-02-17 1984-09-26 Merrell Dow Pharma Dry mix cellulose ether compositions as bulk laxatives
US4517179A (en) 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
JPS6028915A (ja) 1983-07-26 1985-02-14 Eisai Co Ltd ユビデカレノン高含量含有組成物
US4476134A (en) 1983-08-01 1984-10-09 The Upjohn Company Process for treating panic disorders
SE8601624D0 (sv) 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
IT1200178B (it) 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
JPH0618774B2 (ja) 1986-10-09 1994-03-16 塩野義製薬株式会社 糖衣錠の製造方法
WO1988004292A1 (en) 1986-12-11 1988-06-16 The Upjohn Company Antipsychotic amino-polyhydro-benz-(iso)quinolines and intermediates
JPS63222112A (ja) 1987-03-10 1988-09-16 Nippon Soda Co Ltd 徐放性顆粒
JPS63280023A (ja) 1987-05-11 1988-11-17 Yoshitomi Pharmaceut Ind Ltd 抗リウマチ薬
NO883326L (no) 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
JPH01168619A (ja) 1987-12-24 1989-07-04 Takada Seiyaku Kk 新規な酢酸クロルマジノン固形製剤
US4866046A (en) 1988-05-31 1989-09-12 Top Laboratories, Inc. Low-dosage sublingual aspirin
US5292520A (en) 1990-09-13 1994-03-08 Akzo N.V. Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
ES2066092T3 (es) 1990-11-29 1995-03-01 Wei Ming Pharmaceutical Mfg Co Coadyuvante para la formacion directa de comprimidos.
JPH0515319A (ja) 1990-12-14 1993-01-26 Sunstar Inc 水難溶性塩類の分散法およびそれを分散してなる飲用組成物
US5403593A (en) * 1991-03-04 1995-04-04 Sandoz Ltd. Melt granulated compositions for preparing sustained release dosage forms
JPH05139973A (ja) 1991-11-20 1993-06-08 Shin Etsu Chem Co Ltd ニフエジピン含有固形製剤の製造方法
WO1993013756A1 (fr) 1992-01-10 1993-07-22 Obschestvo S Ogranichennoy Otvetstvennostyu Meditsinsky Nauchno-Proizvodstvennoy Komplex 'biotiki' Composition pharmaceutique granulee et son procede de production
EP0639567A1 (en) * 1992-05-08 1995-02-22 Otsuka Pharmaceutical Factory, Inc. Indole derivative
IT1255522B (it) 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
DE4333190C2 (de) 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung
US5496884A (en) 1993-11-12 1996-03-05 Lord Corporation Aqueous adhesive for bonding elastomers
TW355683B (en) * 1994-02-17 1999-04-11 Janssen Pharmaceutica Nv Composition containing micronized nebivolol
JPH07267850A (ja) 1994-03-28 1995-10-17 Eisai Co Ltd 不快味を防止した医薬組成物及びその製造方法
US5543099A (en) 1994-09-29 1996-08-06 Hallmark Pharmaceutical, Inc. Process to manufacture micronized nifedipine granules for sustained release medicaments
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
AR017512A1 (es) 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA

Also Published As

Publication number Publication date
US20030049315A1 (en) 2003-03-13
NZ502890A (en) 2002-03-01
CN1240374C (zh) 2006-02-08
MY137768A (en) 2009-03-31
PL338786A1 (en) 2000-11-20
CN1276718A (zh) 2000-12-13
US7132114B2 (en) 2006-11-07
AU9114698A (en) 1999-03-16
AR049057A2 (es) 2006-06-21
KR20010023198A (ko) 2001-03-26
EA200000245A1 (ru) 2000-08-28
AU745682B2 (en) 2002-03-28
JP2001513546A (ja) 2001-09-04
HUP0003186A3 (en) 2001-04-28
EA003663B1 (ru) 2003-08-28
BR9811987A (pt) 2000-09-05
CA2301132A1 (en) 1999-03-04
UA70926C2 (uk) 2004-11-15
AR049055A2 (es) 2006-06-21
WO1999009959A1 (en) 1999-03-04
TWI228421B (en) 2005-03-01
EP1014949A4 (en) 2006-06-21
AR016827A1 (es) 2001-08-01
EP1014949A1 (en) 2000-07-05
CA2301132C (en) 2007-11-13
US6372253B1 (en) 2002-04-16
HUP0003186A2 (hu) 2001-02-28

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