CO2020001743A2 - Métodos de tratamiento para la fibrosis quística - Google Patents

Métodos de tratamiento para la fibrosis quística

Info

Publication number
CO2020001743A2
CO2020001743A2 CONC2020/0001743A CO2020001743A CO2020001743A2 CO 2020001743 A2 CO2020001743 A2 CO 2020001743A2 CO 2020001743 A CO2020001743 A CO 2020001743A CO 2020001743 A2 CO2020001743 A2 CO 2020001743A2
Authority
CO
Colombia
Prior art keywords
cystic fibrosis
treatment methods
compound
methods
comprised
Prior art date
Application number
CONC2020/0001743A
Other languages
English (en)
Inventor
Eric L Haseltine
Samuel Moskowitz
Sarah Robertson
David Waltz
Weichao George Chen
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of CO2020001743A2 publication Critical patent/CO2020001743A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compuesto I de la fórmula (I) . y/o su o sus sales farmacéuticamente aceptables del Compuesto I comprendido en una composición farmacéutica y métodos para su uso para tratar la fibrosis quística.
CONC2020/0001743A 2017-07-17 2020-02-14 Métodos de tratamiento para la fibrosis quística CO2020001743A2 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762533392P 2017-07-17 2017-07-17
US201762562029P 2017-09-22 2017-09-22
US201862623748P 2018-01-30 2018-01-30
US201862633024P 2018-02-20 2018-02-20
US201862657508P 2018-04-13 2018-04-13
PCT/US2018/042486 WO2019018395A1 (en) 2017-07-17 2018-07-17 METHODS OF TREATING CYSTIC FIBROSIS

Publications (1)

Publication Number Publication Date
CO2020001743A2 true CO2020001743A2 (es) 2020-02-28

Family

ID=63104078

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2020/0001743A CO2020001743A2 (es) 2017-07-17 2020-02-14 Métodos de tratamiento para la fibrosis quística

Country Status (10)

Country Link
US (2) US11517564B2 (es)
EP (1) EP3654969A1 (es)
AU (2) AU2018304168B2 (es)
BR (1) BR112020000941A2 (es)
CA (1) CA3069226A1 (es)
CL (1) CL2020000122A1 (es)
CO (1) CO2020001743A2 (es)
IL (1) IL272032A (es)
MA (1) MA49631A (es)
WO (1) WO2019018395A1 (es)

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TW202120517A (zh) 2019-08-14 2021-06-01 美商維泰克斯製藥公司 製備cftr調節劑之方法
TW202333699A (zh) * 2022-02-03 2023-09-01 美商維泰克斯製藥公司 囊腫纖維化之治療方法
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