CN1946479A - 一种制备分离基质的方法 - Google Patents

一种制备分离基质的方法 Download PDF

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Publication number
CN1946479A
CN1946479A CNA2005800121274A CN200580012127A CN1946479A CN 1946479 A CN1946479 A CN 1946479A CN A2005800121274 A CNA2005800121274 A CN A2005800121274A CN 200580012127 A CN200580012127 A CN 200580012127A CN 1946479 A CN1946479 A CN 1946479A
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CN
China
Prior art keywords
polymerization
matrix
polymer
monomer
base matrix
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Pending
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CNA2005800121274A
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English (en)
Chinese (zh)
Inventor
P·布森
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Cytiva Sweden AB
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GE Healthcare Bio Sciences AB
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Publication of CN1946479A publication Critical patent/CN1946479A/zh
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3861—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Polymerisation Methods In General (AREA)
  • Polymerization Catalysts (AREA)
CNA2005800121274A 2004-04-05 2005-03-31 一种制备分离基质的方法 Pending CN1946479A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0400916A SE0400916D0 (sv) 2004-04-05 2004-04-05 Polymeric ligands
SE04009163 2004-04-05

Publications (1)

Publication Number Publication Date
CN1946479A true CN1946479A (zh) 2007-04-11

Family

ID=32173692

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800121274A Pending CN1946479A (zh) 2004-04-05 2005-03-31 一种制备分离基质的方法

Country Status (8)

Country Link
US (1) US20070193954A1 (https=)
EP (1) EP1732682A1 (https=)
JP (1) JP2007531891A (https=)
CN (1) CN1946479A (https=)
AU (1) AU2005231226A1 (https=)
CA (1) CA2559777A1 (https=)
SE (1) SE0400916D0 (https=)
WO (1) WO2005098415A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
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CN102119177A (zh) * 2008-08-11 2011-07-06 赢创高施米特有限公司 分散剂及其用途
CN108371948A (zh) * 2018-02-09 2018-08-07 安徽师范大学 新型亲和嗜硫硅球色谱材料及其制备方法和应用
CN109932224A (zh) * 2017-12-18 2019-06-25 中国科学院大连化学物理研究所 一种富集提取循环肿瘤dna的方法
CN109929832A (zh) * 2017-12-18 2019-06-25 中国科学院大连化学物理研究所 一种双组分聚合物功能化材料富集提取循环肿瘤dna的方法
CN114749162A (zh) * 2016-07-14 2022-07-15 纯化迪发有限公司 包含聚合物纳米纤维的官能化色谱介质及其制备方法
CN115326937A (zh) * 2021-05-11 2022-11-11 山东省食品药品检验研究院 一种基因毒杂质捕捉用固相探针及其使用方法与应用

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US9012239B2 (en) 2006-05-27 2015-04-21 Fluidigm Canada Inc. Polymer backbone element tags
EP2043776A4 (en) * 2006-05-29 2009-12-30 Ge Healthcare Bio Sciences Ab PREPARATION OF MONOLITHIC ARTICLES
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
CA2655873C (en) 2006-07-14 2017-10-17 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
AU2013201133B2 (en) * 2007-03-28 2014-02-27 Patheon Holdings I B.V. Expanded bed column and disposable chromatography
JP5888481B2 (ja) * 2007-03-28 2016-03-22 ディーピーエックス ホールディングス ビー．ブイ． 膨張床カラムおよび使い捨て可能なクロマトグラフィー
WO2009151514A1 (en) 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
US20100051554A1 (en) * 2008-08-28 2010-03-04 Dong June Ahn Molecular basket coated micro particles
CN102257122B (zh) 2008-12-16 2015-07-29 Emd密理博公司 搅拌槽反应器及方法
CN107312062B (zh) 2010-05-17 2021-03-16 Emd密理博公司 用于纯化生物分子的刺激响应性聚合物
JP5631271B2 (ja) * 2010-07-28 2014-11-26 ローム アンド ハース カンパニーＲｏｈｍ Ａｎｄ Ｈａａｓ Ｃｏｍｐａｎｙ 改良されたクロマトグラフィー媒体の製造方法および使用方法
JP5474881B2 (ja) * 2010-07-28 2014-04-16 ローム アンド ハース カンパニー 向上したクロマトグラフィー媒体の製造方法および使用方法
US20130225701A1 (en) 2010-07-29 2013-08-29 Emd Millipore Corporation Grafting method to improve chromatography media performance
JP5693944B2 (ja) * 2010-12-22 2015-04-01 旭化成ケミカルズ株式会社 成膜性を有する有機−無機複合体及びその製造方法
JP2015212620A (ja) * 2012-08-28 2015-11-26 信和化工株式会社 コアシェル粒子の製造方法
RU2015114330A (ru) 2012-09-17 2016-11-10 У.Р. Грейс Энд Ко.-Конн. Хроматографические среды и устройства
WO2014043644A1 (en) 2012-09-17 2014-03-20 Alltech Associates, Inc. Functionalized particulate support material and methods of making and using the same
CN105658325A (zh) * 2013-10-10 2016-06-08 通用电气医疗集团生物工艺研发股份公司 生产色谱材料的方法
US11229896B2 (en) 2014-01-16 2022-01-25 W.R. Grace & Co.—Conn. Affinity chromatography media and chromatography devices
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 官能化担体材料並びに官能化担体材料を作製及び使用する方法
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
RU2745388C2 (ru) 2016-05-31 2021-03-24 Као Корпорейшн Способ стирки одежды
EP3759148A1 (en) 2018-02-27 2021-01-06 Waters Technologies Corporation Polymer particles with a gradient composition and methods of production thereof
CN112105927B (zh) 2018-05-08 2024-06-25 沃特世科技公司 可用于pH梯度阳离子交换色谱法的方法、组合物和试剂盒
CN109865312A (zh) * 2019-03-21 2019-06-11 青海大学 一种基于铷萃取的氨基及十八冠六醚修饰的磁性固相萃取剂的制备方法

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US5059654A (en) * 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
US5030352A (en) * 1990-01-25 1991-07-09 Purdue Research Foundation Coated media for chromatography
DE59406939D1 (en) * 1993-07-16 1998-10-22 Merck Patent Gmbh Trennmaterialien für die hydrophobe chromatographie
WO1998033064A1 (en) * 1997-01-24 1998-07-30 Amersham Pharmacia Biotech K.K. Method for separating pth amino acids
ATE301679T1 (de) * 1999-01-29 2005-08-15 Amersham Biosciences Kk Temperatursensitives polymer und verfahren zu seiner herstellung
US6716949B2 (en) * 2001-09-20 2004-04-06 Hewlett-Packard Development Company, L.P. Amphipathic polymer particles and methods of manufacturing the same
JP4174330B2 (ja) * 2002-01-21 2008-10-29 株式会社カネカ ビニル系重合体の製造方法、ビニル系重合体及び硬化性組成物

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102119177A (zh) * 2008-08-11 2011-07-06 赢创高施米特有限公司 分散剂及其用途
CN102119177B (zh) * 2008-08-11 2014-01-15 赢创高施米特有限公司 分散剂及其用途
CN114749162A (zh) * 2016-07-14 2022-07-15 纯化迪发有限公司 包含聚合物纳米纤维的官能化色谱介质及其制备方法
CN109932224A (zh) * 2017-12-18 2019-06-25 中国科学院大连化学物理研究所 一种富集提取循环肿瘤dna的方法
CN109929832A (zh) * 2017-12-18 2019-06-25 中国科学院大连化学物理研究所 一种双组分聚合物功能化材料富集提取循环肿瘤dna的方法
CN108371948A (zh) * 2018-02-09 2018-08-07 安徽师范大学 新型亲和嗜硫硅球色谱材料及其制备方法和应用
CN115326937A (zh) * 2021-05-11 2022-11-11 山东省食品药品检验研究院 一种基因毒杂质捕捉用固相探针及其使用方法与应用

Also Published As

Publication number Publication date
WO2005098415A1 (en) 2005-10-20
CA2559777A1 (en) 2005-10-20
US20070193954A1 (en) 2007-08-23
SE0400916D0 (sv) 2004-04-05
EP1732682A1 (en) 2006-12-20
JP2007531891A (ja) 2007-11-08
AU2005231226A1 (en) 2005-10-20

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Application publication date: 20070411