CA2559777A1 - A method of preparing a separation matrix - Google Patents
A method of preparing a separation matrix Download PDFInfo
- Publication number
- CA2559777A1 CA2559777A1 CA002559777A CA2559777A CA2559777A1 CA 2559777 A1 CA2559777 A1 CA 2559777A1 CA 002559777 A CA002559777 A CA 002559777A CA 2559777 A CA2559777 A CA 2559777A CA 2559777 A1 CA2559777 A1 CA 2559777A1
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- Prior art keywords
- polymerisation
- matrix
- polymers
- chromatography
- monomers
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- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 150000003568 thioethers Chemical class 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 150000003623 transition metal compounds Chemical class 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B01J20/287—Non-polar phases; Reversed phases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3278—Polymers being grafted on the carrier
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/328—Polymers on the carrier being further modified
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3861—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Polymerisation Methods In General (AREA)
- Polymerization Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400916A SE0400916D0 (sv) | 2004-04-05 | 2004-04-05 | Polymeric ligands |
| SE0400916-3 | 2004-04-05 | ||
| PCT/SE2005/000468 WO2005098415A1 (en) | 2004-04-05 | 2005-03-31 | A method of preparing a separation matrix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2559777A1 true CA2559777A1 (en) | 2005-10-20 |
Family
ID=32173692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002559777A Abandoned CA2559777A1 (en) | 2004-04-05 | 2005-03-31 | A method of preparing a separation matrix |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070193954A1 (https=) |
| EP (1) | EP1732682A1 (https=) |
| JP (1) | JP2007531891A (https=) |
| CN (1) | CN1946479A (https=) |
| AU (1) | AU2005231226A1 (https=) |
| CA (1) | CA2559777A1 (https=) |
| SE (1) | SE0400916D0 (https=) |
| WO (1) | WO2005098415A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9012239B2 (en) | 2006-05-27 | 2015-04-21 | Fluidigm Canada Inc. | Polymer backbone element tags |
| EP2043776A4 (en) * | 2006-05-29 | 2009-12-30 | Ge Healthcare Bio Sciences Ab | PREPARATION OF MONOLITHIC ARTICLES |
| FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
| CA2655873C (en) | 2006-07-14 | 2017-10-17 | Wisconsin Alumni Research Foundation | Adsorptive membranes for trapping viruses |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| WO2008079280A1 (en) | 2006-12-21 | 2008-07-03 | Millipore Corporation | Purification of proteins |
| AU2013201133B2 (en) * | 2007-03-28 | 2014-02-27 | Patheon Holdings I B.V. | Expanded bed column and disposable chromatography |
| JP5888481B2 (ja) * | 2007-03-28 | 2016-03-22 | ディーピーエックス ホールディングス ビー．ブイ． | 膨張床カラムおよび使い捨て可能なクロマトグラフィー |
| WO2009151514A1 (en) | 2008-06-11 | 2009-12-17 | Millipore Corporation | Stirred tank bioreactor |
| DE102008041139A1 (de) * | 2008-08-11 | 2010-02-18 | Evonik Goldschmidt Gmbh | Dispergiermittel und dessen Verwendung |
| US20100051554A1 (en) * | 2008-08-28 | 2010-03-04 | Dong June Ahn | Molecular basket coated micro particles |
| CN102257122B (zh) | 2008-12-16 | 2015-07-29 | Emd密理博公司 | 搅拌槽反应器及方法 |
| CN107312062B (zh) | 2010-05-17 | 2021-03-16 | Emd密理博公司 | 用于纯化生物分子的刺激响应性聚合物 |
| JP5631271B2 (ja) * | 2010-07-28 | 2014-11-26 | ローム アンド ハース カンパニーＲｏｈｍ Ａｎｄ Ｈａａｓ Ｃｏｍｐａｎｙ | 改良されたクロマトグラフィー媒体の製造方法および使用方法 |
| JP5474881B2 (ja) * | 2010-07-28 | 2014-04-16 | ローム アンド ハース カンパニー | 向上したクロマトグラフィー媒体の製造方法および使用方法 |
| US20130225701A1 (en) | 2010-07-29 | 2013-08-29 | Emd Millipore Corporation | Grafting method to improve chromatography media performance |
| JP5693944B2 (ja) * | 2010-12-22 | 2015-04-01 | 旭化成ケミカルズ株式会社 | 成膜性を有する有機−無機複合体及びその製造方法 |
| JP2015212620A (ja) * | 2012-08-28 | 2015-11-26 | 信和化工株式会社 | コアシェル粒子の製造方法 |
| RU2015114330A (ru) | 2012-09-17 | 2016-11-10 | У.Р. Грейс Энд Ко.-Конн. | Хроматографические среды и устройства |
| WO2014043644A1 (en) | 2012-09-17 | 2014-03-20 | Alltech Associates, Inc. | Functionalized particulate support material and methods of making and using the same |
| CN105658325A (zh) * | 2013-10-10 | 2016-06-08 | 通用电气医疗集团生物工艺研发股份公司 | 生产色谱材料的方法 |
| US11229896B2 (en) | 2014-01-16 | 2022-01-25 | W.R. Grace & Co.—Conn. | Affinity chromatography media and chromatography devices |
| JP6914189B2 (ja) | 2014-05-02 | 2021-08-04 | ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ | 官能化担体材料並びに官能化担体材料を作製及び使用する方法 |
| CN107921407B (zh) | 2015-06-05 | 2022-07-05 | 格雷斯公司 | 生物处理吸附澄清剂及其制备和使用方法 |
| RU2745388C2 (ru) | 2016-05-31 | 2021-03-24 | Као Корпорейшн | Способ стирки одежды |
| CN114749162B (zh) * | 2016-07-14 | 2025-04-08 | 思拓凡生物工艺研发有限公司 | 包含聚合物纳米纤维的官能化色谱介质及其制备方法 |
| CN109932224A (zh) * | 2017-12-18 | 2019-06-25 | 中国科学院大连化学物理研究所 | 一种富集提取循环肿瘤dna的方法 |
| CN109929832A (zh) * | 2017-12-18 | 2019-06-25 | 中国科学院大连化学物理研究所 | 一种双组分聚合物功能化材料富集提取循环肿瘤dna的方法 |
| CN108371948A (zh) * | 2018-02-09 | 2018-08-07 | 安徽师范大学 | 新型亲和嗜硫硅球色谱材料及其制备方法和应用 |
| EP3759148A1 (en) | 2018-02-27 | 2021-01-06 | Waters Technologies Corporation | Polymer particles with a gradient composition and methods of production thereof |
| CN112105927B (zh) | 2018-05-08 | 2024-06-25 | 沃特世科技公司 | 可用于pH梯度阳离子交换色谱法的方法、组合物和试剂盒 |
| CN109865312A (zh) * | 2019-03-21 | 2019-06-11 | 青海大学 | 一种基于铷萃取的氨基及十八冠六醚修饰的磁性固相萃取剂的制备方法 |
| CN115326937B (zh) * | 2021-05-11 | 2024-06-18 | 山东省食品药品检验研究院 | 一种基因毒杂质捕捉用固相探针及其使用方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5059654A (en) * | 1983-02-14 | 1991-10-22 | Cuno Inc. | Affinity matrices of modified polysaccharide supports |
| US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
| DE59406939D1 (en) * | 1993-07-16 | 1998-10-22 | Merck Patent Gmbh | Trennmaterialien für die hydrophobe chromatographie |
| WO1998033064A1 (en) * | 1997-01-24 | 1998-07-30 | Amersham Pharmacia Biotech K.K. | Method for separating pth amino acids |
| ATE301679T1 (de) * | 1999-01-29 | 2005-08-15 | Amersham Biosciences Kk | Temperatursensitives polymer und verfahren zu seiner herstellung |
| US6716949B2 (en) * | 2001-09-20 | 2004-04-06 | Hewlett-Packard Development Company, L.P. | Amphipathic polymer particles and methods of manufacturing the same |
| JP4174330B2 (ja) * | 2002-01-21 | 2008-10-29 | 株式会社カネカ | ビニル系重合体の製造方法、ビニル系重合体及び硬化性組成物 |
-
2004
- 2004-04-05 SE SE0400916A patent/SE0400916D0/xx unknown
-
2005
- 2005-03-31 WO PCT/SE2005/000468 patent/WO2005098415A1/en not_active Ceased
- 2005-03-31 AU AU2005231226A patent/AU2005231226A1/en not_active Abandoned
- 2005-03-31 JP JP2007507271A patent/JP2007531891A/ja active Pending
- 2005-03-31 CA CA002559777A patent/CA2559777A1/en not_active Abandoned
- 2005-03-31 CN CNA2005800121274A patent/CN1946479A/zh active Pending
- 2005-03-31 US US10/592,807 patent/US20070193954A1/en not_active Abandoned
- 2005-03-31 EP EP05722293A patent/EP1732682A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005098415A1 (en) | 2005-10-20 |
| US20070193954A1 (en) | 2007-08-23 |
| CN1946479A (zh) | 2007-04-11 |
| SE0400916D0 (sv) | 2004-04-05 |
| EP1732682A1 (en) | 2006-12-20 |
| JP2007531891A (ja) | 2007-11-08 |
| AU2005231226A1 (en) | 2005-10-20 |
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