CN1926247A - 检测strp例如脆性x染色体综合征 - Google Patents

检测strp例如脆性x染色体综合征 Download PDF

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Publication number
CN1926247A
CN1926247A CNA2005800064661A CN200580006466A CN1926247A CN 1926247 A CN1926247 A CN 1926247A CN A2005800064661 A CNA2005800064661 A CN A2005800064661A CN 200580006466 A CN200580006466 A CN 200580006466A CN 1926247 A CN1926247 A CN 1926247A
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China
Prior art keywords
dna
nucleic acid
labeled
complementary
cgg
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CNA2005800064661A
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English (en)
Chinese (zh)
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S·韩
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Biocept Inc
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Biocept Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2005800064661A 2004-03-01 2005-02-28 检测strp例如脆性x染色体综合征 Pending CN1926247A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/791,209 2004-03-01
US10/791,209 US20050191636A1 (en) 2004-03-01 2004-03-01 Detection of STRP, such as fragile X syndrome

Publications (1)

Publication Number Publication Date
CN1926247A true CN1926247A (zh) 2007-03-07

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ID=34887577

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CNA2005800064661A Pending CN1926247A (zh) 2004-03-01 2005-02-28 检测strp例如脆性x染色体综合征

Country Status (6)

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US (1) US20050191636A1 (enExample)
EP (1) EP1723261A1 (enExample)
JP (1) JP2007525998A (enExample)
KR (1) KR20070011354A (enExample)
CN (1) CN1926247A (enExample)
WO (1) WO2005085476A1 (enExample)

Cited By (9)

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Publication number Priority date Publication date Assignee Title
CN102482718A (zh) * 2009-07-10 2012-05-30 珀金埃尔默健康科学股份有限公司 探测多核苷酸重复
CN102703595A (zh) * 2012-06-13 2012-10-03 东南大学 一种碱基选择性可控延伸的str序列高通量检测方法及其检测试剂
CN102952794A (zh) * 2012-09-05 2013-03-06 张家港蓝苏生物工程有限公司 靶向基因dna分子探针的制备方法
CN103998624A (zh) * 2011-09-19 2014-08-20 艾皮斯托姆有限公司 具有多个靶区域特异性和具有分为三部分特征的探针
CN104053790A (zh) * 2012-01-18 2014-09-17 泰肯贸易股份公司 通过差异杂交进行的str基因分型
CN104498600A (zh) * 2014-12-10 2015-04-08 东南大学 一种基于磁珠与核酸水解分离发光标记物的核酸检测方法
CN104531851A (zh) * 2014-12-10 2015-04-22 东南大学 一种基于磁珠与多糖水解分离发光标记物的核酸检测方法
CN108300776A (zh) * 2017-01-13 2018-07-20 金赟懿 脆性x综合征快速筛查试剂盒
CN111819289A (zh) * 2018-01-05 2020-10-23 酷商瑞士股份公司 自组装诊断阵列平台

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US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
WO2004029221A2 (en) 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US7468249B2 (en) * 2004-05-05 2008-12-23 Biocept, Inc. Detection of chromosomal disorders
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
EP1857548A1 (en) 2006-05-19 2007-11-21 Academisch Ziekenhuis Leiden Means and method for inducing exon-skipping
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
EP2589668A1 (en) 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2007147074A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Use of highly parallel snp genotyping for fetal diagnosis
PT2049664E (pt) 2006-08-11 2012-01-03 Prosensa Technologies Bv Oligonucleotídeos de cadeia simples complementares dos elementos repetitivos para tratar perturbações genéticas associadas à instabilidade das repetições do adn
WO2009008725A2 (en) 2007-07-12 2009-01-15 Prosensa Technologies B.V. Molecules for targeting compounds to various selected organs, tissues or tumor cells
DK2167136T3 (en) 2007-07-12 2016-07-25 Biomarin Tech Bv Molecules for targeting compounds at different selected organs or tissues
WO2009045467A1 (en) * 2007-10-02 2009-04-09 Fred Hutchinson Cancer Research Center Methods and compositions for identifying increased risk of developing fragile x-associated disorders
PL2203173T3 (pl) 2007-10-26 2016-06-30 Academisch Ziekenhuis Leiden Środki i sposoby przeciwdziałania zaburzeniom mięśni
USRE48468E1 (en) 2007-10-26 2021-03-16 Biomarin Technologies B.V. Means and methods for counteracting muscle disorders
US8008019B2 (en) * 2007-11-28 2011-08-30 Luminex Molecular Diagnostics Use of dual-tags for the evaluation of genomic variable repeat regions
NZ587178A (en) 2008-02-08 2011-11-25 Prosensa Holding Bv Methods and means for treating dna repeat instability associated genetic disorders
EP2119783A1 (en) 2008-05-14 2009-11-18 Prosensa Technologies B.V. Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
US20090298709A1 (en) * 2008-05-28 2009-12-03 Affymetrix, Inc. Assays for determining telomere length and repeated sequence copy number
ES2620294T3 (es) 2008-09-20 2017-06-28 The Board Of Trustees Of The Leland Stanford Junior University Diagnóstico no invasivo de la aneuploidia fetal por secuenciación
WO2010123369A1 (en) 2009-04-24 2010-10-28 Prosensa Technologies B.V. Oligonucleotide comprising an inosine for treating dmd
EP4296370B1 (en) 2010-02-05 2025-11-05 Quest Diagnostics Investments Incorporated Method to detect repeat sequence motifs in nucleic acid
JP2015509922A (ja) 2012-01-27 2015-04-02 プロセンサ テクノロジーズ ビー．ブイ．Ｐｒｏｓｅｎｓａ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｂ．Ｖ． デュシェンヌ型及びベッカー型筋ジストロフィーの治療のための改善された特徴を有するｒｎａ調節オリゴヌクレオチド
US10459666B2 (en) 2017-03-03 2019-10-29 Commvault Systems, Inc. Using storage managers in respective data storage management systems for license distribution, compliance, and updates
GB201803019D0 (en) * 2018-02-26 2018-04-11 Univ Newcastle Methods for detecting target polynucleotides

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DK0724646T3 (da) * 1991-01-04 2001-09-03 Univ Washington DNA sekvenser knyttet til isoleret fragilt X syndrom
US6180337B1 (en) * 1991-05-24 2001-01-30 Baylor College Of Medicine Diagnosis of the fragile X syndrome
US6200747B1 (en) * 1992-01-28 2001-03-13 North Shore University Hospital Research Corp. Method and kits for detection of fragile X specific, GC-rich DNA sequences
WO1994003638A1 (en) * 1992-07-30 1994-02-17 Applied Biosystems, Inc. Method of detecting aneuploidy by amplified short tandem repeats
JP2807612B2 (ja) * 1993-03-12 1998-10-08 ノボ ノルディスク アクティーゼルスカブ 新規キシラナーゼ、その製造法、該キシラナーゼによるパルプ処理方法及びキシロオリゴ糖の製造法
US6120992A (en) * 1993-11-04 2000-09-19 Valigene Corporation Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, and allele identification in a diseased human
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods
US5888740A (en) * 1997-09-19 1999-03-30 Genaco Biomedical Products, Inc. Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls
US6143504A (en) * 1998-10-27 2000-11-07 Arch Development Corporation Methods and compositions for the diagnosis of fragile X syndrome
US6268147B1 (en) * 1998-11-02 2001-07-31 Kenneth Loren Beattie Nucleic acid analysis using sequence-targeted tandem hybridization
US6225061B1 (en) * 1999-03-10 2001-05-01 Sequenom, Inc. Systems and methods for performing reactions in an unsealed environment
US6638719B1 (en) * 1999-07-14 2003-10-28 Affymetrix, Inc. Genotyping biallelic markers
US20040265883A1 (en) * 2003-06-27 2004-12-30 Biocept, Inc. mRNA expression analysis

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102482718A (zh) * 2009-07-10 2012-05-30 珀金埃尔默健康科学股份有限公司 探测多核苷酸重复
CN103998624A (zh) * 2011-09-19 2014-08-20 艾皮斯托姆有限公司 具有多个靶区域特异性和具有分为三部分特征的探针
CN104053790A (zh) * 2012-01-18 2014-09-17 泰肯贸易股份公司 通过差异杂交进行的str基因分型
CN104053790B (zh) * 2012-01-18 2016-03-02 泰肯贸易股份公司 通过差异杂交进行的str基因分型
CN102703595A (zh) * 2012-06-13 2012-10-03 东南大学 一种碱基选择性可控延伸的str序列高通量检测方法及其检测试剂
CN102952794A (zh) * 2012-09-05 2013-03-06 张家港蓝苏生物工程有限公司 靶向基因dna分子探针的制备方法
CN102952794B (zh) * 2012-09-05 2015-02-25 张家港蓝苏生物工程有限公司 靶向基因dna分子探针的制备方法
CN104498600A (zh) * 2014-12-10 2015-04-08 东南大学 一种基于磁珠与核酸水解分离发光标记物的核酸检测方法
CN104531851A (zh) * 2014-12-10 2015-04-22 东南大学 一种基于磁珠与多糖水解分离发光标记物的核酸检测方法
CN108300776A (zh) * 2017-01-13 2018-07-20 金赟懿 脆性x综合征快速筛查试剂盒
CN111819289A (zh) * 2018-01-05 2020-10-23 酷商瑞士股份公司 自组装诊断阵列平台

Also Published As

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JP2007525998A (ja) 2007-09-13
EP1723261A1 (en) 2006-11-22
KR20070011354A (ko) 2007-01-24
US20050191636A1 (en) 2005-09-01
WO2005085476A1 (en) 2005-09-15

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