CN1856327A - Vegf受体抑制剂与化疗剂的组合 - Google Patents

Vegf受体抑制剂与化疗剂的组合 Download PDF

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Publication number
CN1856327A
CN1856327A CNA2004800275441A CN200480027544A CN1856327A CN 1856327 A CN1856327 A CN 1856327A CN A2004800275441 A CNA2004800275441 A CN A2004800275441A CN 200480027544 A CN200480027544 A CN 200480027544A CN 1856327 A CN1856327 A CN 1856327A
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CN
China
Prior art keywords
inhibitor
group
independently
amino
chemical compound
Prior art date
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Pending
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CNA2004800275441A
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English (en)
Chinese (zh)
Inventor
G·博尔德
J·B·步吕根
J·M－J·黄
F·R·小金德
H·莱恩
E·J·拉图尔
P·W·曼利
J·M·伍德
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Novartis AG
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Novartis AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2004800275441A 2003-09-23 2004-09-23 Vegf受体抑制剂与化疗剂的组合 Pending CN1856327A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50525003P 2003-09-23 2003-09-23
US60/505,250 2003-09-23

Publications (1)

Publication Number Publication Date
CN1856327A true CN1856327A (zh) 2006-11-01

Family

ID=34375569

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800275441A Pending CN1856327A (zh) 2003-09-23 2004-09-23 Vegf受体抑制剂与化疗剂的组合

Country Status (16)

Country Link
US (1) US20080085902A1 (enExample)
EP (1) EP1682181A2 (enExample)
JP (1) JP2007505938A (enExample)
KR (1) KR20060097000A (enExample)
CN (1) CN1856327A (enExample)
AU (1) AU2004273615B2 (enExample)
BR (1) BRPI0414698A (enExample)
CA (1) CA2537991A1 (enExample)
CO (1) CO5680459A2 (enExample)
CR (1) CR8283A (enExample)
EA (1) EA200600495A1 (enExample)
EC (1) ECSP066437A (enExample)
IL (1) IL174214A0 (enExample)
MX (1) MXPA06003163A (enExample)
NO (1) NO20061777L (enExample)
WO (1) WO2005027972A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102655863A (zh) * 2009-09-30 2012-09-05 株式会社资生堂 乙酰肝素酶活性抑制剂
WO2025160930A1 (zh) * 2024-02-02 2025-08-07 基亚生物科技股份有限公司 母帕司汀(Muparfostat)治疗胰腺癌的用途

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CN102655863A (zh) * 2009-09-30 2012-09-05 株式会社资生堂 乙酰肝素酶活性抑制剂
CN102655863B (zh) * 2009-09-30 2013-11-20 株式会社资生堂 乙酰肝素酶活性抑制剂
WO2025160930A1 (zh) * 2024-02-02 2025-08-07 基亚生物科技股份有限公司 母帕司汀(Muparfostat)治疗胰腺癌的用途

Also Published As

Publication number Publication date
AU2004273615A1 (en) 2005-03-31
KR20060097000A (ko) 2006-09-13
MXPA06003163A (es) 2006-06-05
IL174214A0 (en) 2006-08-01
CA2537991A1 (en) 2005-03-31
EP1682181A2 (en) 2006-07-26
AU2004273615B2 (en) 2009-01-15
BRPI0414698A (pt) 2006-11-28
US20080085902A1 (en) 2008-04-10
CO5680459A2 (es) 2006-09-29
NO20061777L (no) 2006-06-23
CR8283A (es) 2006-10-10
ECSP066437A (es) 2006-09-18
WO2005027972A3 (en) 2005-11-03
WO2005027972A2 (en) 2005-03-31
JP2007505938A (ja) 2007-03-15
EA200600495A1 (ru) 2006-10-27

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Open date: 20061101