JP2007505938A - Ｖｅｇｆ受容体阻害剤と化学療法剤の組み合わせ - Google Patents

Ｖｅｇｆ受容体阻害剤と化学療法剤の組み合わせ Download PDF

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Publication number
JP2007505938A
JP2007505938A JP2006527348A JP2006527348A JP2007505938A JP 2007505938 A JP2007505938 A JP 2007505938A JP 2006527348 A JP2006527348 A JP 2006527348A JP 2006527348 A JP2006527348 A JP 2006527348A JP 2007505938 A JP2007505938 A JP 2007505938A
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inhibitor
inhibitors
group
lower alkyl
independently
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JP2007505938A5 (enExample
Inventor
グイド・ボルト
ヨーゼフ・ベルンハルト・ブリューゲン
ジェリー・ミン−ジャン・フアン
フレデリック・レイ・カインダー・ジュニア
ハイディ・ラーネ
エリザベート・ジャンヌ・ラトゥール
ポール・ウィリアム・マンリー
ジャネット・マージョリー・ウッド
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ノバルティス アクチエンゲゼルシャフト
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Publication of JP2007505938A publication Critical patent/JP2007505938A/ja
Publication of JP2007505938A5 publication Critical patent/JP2007505938A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006527348A 2003-09-23 2004-09-23 Ｖｅｇｆ受容体阻害剤と化学療法剤の組み合わせ Pending JP2007505938A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50525003P 2003-09-23 2003-09-23
PCT/EP2004/010686 WO2005027972A2 (en) 2003-09-23 2004-09-23 Combination of a vegf receptor inhibitor with a chemotherapeutic agent

Publications (2)

Publication Number Publication Date
JP2007505938A true JP2007505938A (ja) 2007-03-15
JP2007505938A5 JP2007505938A5 (enExample) 2007-11-08

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ID=34375569

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JP2006527348A Pending JP2007505938A (ja) 2003-09-23 2004-09-23 Ｖｅｇｆ受容体阻害剤と化学療法剤の組み合わせ

Country Status (16)

Country Link
US (1) US20080085902A1 (enExample)
EP (1) EP1682181A2 (enExample)
JP (1) JP2007505938A (enExample)
KR (1) KR20060097000A (enExample)
CN (1) CN1856327A (enExample)
AU (1) AU2004273615B2 (enExample)
BR (1) BRPI0414698A (enExample)
CA (1) CA2537991A1 (enExample)
CO (1) CO5680459A2 (enExample)
CR (1) CR8283A (enExample)
EA (1) EA200600495A1 (enExample)
EC (1) ECSP066437A (enExample)
IL (1) IL174214A0 (enExample)
MX (1) MXPA06003163A (enExample)
NO (1) NO20061777L (enExample)
WO (1) WO2005027972A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008514576A (ja) * 2004-09-27 2008-05-08 アストラゼネカ アクチボラグ Ａｚｄ２１７１およびイマチニブを含む癌組合せ療法
WO2011087066A1 (ja) 2010-01-14 2011-07-21 株式会社三和化学研究所 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬
JP2012517434A (ja) * 2009-02-06 2012-08-02 ザ ジェネラル ホスピタル コーポレイション 血管病変を治療する方法
WO2012105610A1 (ja) 2011-02-02 2012-08-09 公立大学法人名古屋市立大学 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬

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HU230302B1 (hu) 2000-10-20 2015-12-28 Eisai R&D Management Co., Ltd. Nitrogéntartalmú aromás származékok és ezeket tartalmazó gyógyászati készítmények
EP1478358B1 (en) 2002-02-11 2013-07-03 Bayer HealthCare LLC Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis
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EA010485B1 (ru) 2003-07-23 2008-10-30 Байер Фамэсьютиклс Копэрейшн Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
CN101337930B (zh) 2003-11-11 2010-09-08 卫材R&D管理有限公司 脲衍生物的制备方法
WO2005070020A2 (en) 2004-01-23 2005-08-04 The Regents Of The University Of Colorado Gefitinib sensitivity-related gene expression and products and methods related thereto
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ES2556173T3 (es) 2006-05-18 2016-01-13 Eisai R&D Management Co., Ltd. Agente antitumoral para un cáncer de tiroides
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KR101433629B1 (ko) 2006-09-11 2014-08-27 쿠리스 인코퍼레이션 아연 결합 부분을 함유한 티로신 키나아제 억제제
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EP2030615A3 (en) 2007-08-13 2009-12-02 ELFORD, Howard L. Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases
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JP5647098B2 (ja) 2008-03-21 2014-12-24 ザ ユニヴァーシティー オヴ シカゴ オピオイド拮抗薬とｍＴＯＲ阻害薬を用いた治療
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Cited By (6)

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JP2008514576A (ja) * 2004-09-27 2008-05-08 アストラゼネカ アクチボラグ Ａｚｄ２１７１およびイマチニブを含む癌組合せ療法
JP2012517434A (ja) * 2009-02-06 2012-08-02 ザ ジェネラル ホスピタル コーポレイション 血管病変を治療する方法
JP2015129119A (ja) * 2009-02-06 2015-07-16 ザ ジェネラル ホスピタル コーポレイション 血管病変を治療する方法
US9186336B2 (en) 2009-02-06 2015-11-17 The General Hospital Corporation Methods of treating vascular lesions
WO2011087066A1 (ja) 2010-01-14 2011-07-21 株式会社三和化学研究所 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬
WO2012105610A1 (ja) 2011-02-02 2012-08-09 公立大学法人名古屋市立大学 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬

Also Published As

Publication number Publication date
EA200600495A1 (ru) 2006-10-27
KR20060097000A (ko) 2006-09-13
US20080085902A1 (en) 2008-04-10
NO20061777L (no) 2006-06-23
AU2004273615A1 (en) 2005-03-31
WO2005027972A2 (en) 2005-03-31
CO5680459A2 (es) 2006-09-29
AU2004273615B2 (en) 2009-01-15
MXPA06003163A (es) 2006-06-05
CR8283A (es) 2006-10-10
ECSP066437A (es) 2006-09-18
BRPI0414698A (pt) 2006-11-28
CA2537991A1 (en) 2005-03-31
CN1856327A (zh) 2006-11-01
EP1682181A2 (en) 2006-07-26
WO2005027972A3 (en) 2005-11-03
IL174214A0 (en) 2006-08-01

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