CN1545509A - 用作趋化因子受体活性调节剂的哌啶衍生物 - Google Patents

用作趋化因子受体活性调节剂的哌啶衍生物 Download PDF

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Publication number
CN1545509A
CN1545509A CNA028162714A CN02816271A CN1545509A CN 1545509 A CN1545509 A CN 1545509A CN A028162714 A CNA028162714 A CN A028162714A CN 02816271 A CN02816271 A CN 02816271A CN 1545509 A CN1545509 A CN 1545509A
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China
Prior art keywords
alkyl
compound
formula
carbonyl
dichlorophenoxy
Prior art date
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Pending
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CNA028162714A
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English (en)
Chinese (zh)
Inventor
¡
理查德·埃文斯
马修·佩里
布赖恩·斯普林索普
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AstraZeneca AB
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AstraZeneca AB
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Priority claimed from GB0116179A external-priority patent/GB0116179D0/en
Priority claimed from GB0123037A external-priority patent/GB0123037D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1545509A publication Critical patent/CN1545509A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
CNA028162714A 2001-07-02 2002-07-01 用作趋化因子受体活性调节剂的哌啶衍生物 Pending CN1545509A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0116179.3 2001-07-02
GB0116179A GB0116179D0 (en) 2001-07-02 2001-07-02 Chemical compounds
GB0123037.4 2001-09-25
GB0123037A GB0123037D0 (en) 2001-09-25 2001-09-25 Chemical compounds

Publications (1)

Publication Number Publication Date
CN1545509A true CN1545509A (zh) 2004-11-10

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CNA028162714A Pending CN1545509A (zh) 2001-07-02 2002-07-01 用作趋化因子受体活性调节剂的哌啶衍生物

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Country Link
US (1) US7307090B2 (enExample)
EP (2) EP1604982A1 (enExample)
JP (1) JP3857270B2 (enExample)
KR (1) KR20040013090A (enExample)
CN (1) CN1545509A (enExample)
AR (1) AR042401A1 (enExample)
AT (1) ATE319703T1 (enExample)
BR (1) BR0210733A (enExample)
CA (1) CA2452597A1 (enExample)
CO (1) CO5540307A2 (enExample)
CY (1) CY1106095T1 (enExample)
DE (1) DE60209736T2 (enExample)
DK (1) DK1404667T3 (enExample)
ES (1) ES2258642T3 (enExample)
HU (1) HUP0401886A2 (enExample)
IL (1) IL159256A0 (enExample)
IS (1) IS7094A (enExample)
MX (1) MXPA03011722A (enExample)
NO (1) NO20035729L (enExample)
NZ (1) NZ530202A (enExample)
PL (1) PL368041A1 (enExample)
PT (1) PT1404667E (enExample)
RU (1) RU2004100839A (enExample)
SA (1) SA02230184B1 (enExample)
WO (1) WO2003004487A1 (enExample)

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SE0302956D0 (sv) * 2003-11-07 2003-11-07 Astrazeneca Ab Chemical compounds
SE0400925D0 (sv) * 2004-04-06 2004-04-06 Astrazeneca Ab Chemical compounds
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CN111918862A (zh) * 2018-02-27 2020-11-10 组合化学工业株式会社 巯基酚化合物的制造方法及其中间体
CN111918862B (zh) * 2018-02-27 2022-01-18 组合化学工业株式会社 巯基酚化合物的制造方法及其中间体
CN114478336A (zh) * 2018-02-27 2022-05-13 组合化学工业株式会社 巯基酚化合物的制造方法及其中间体
CN114478336B (zh) * 2018-02-27 2024-05-14 组合化学工业株式会社 巯基酚化合物的制造方法及其中间体

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