ATE319703T1 - Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen - Google Patents

Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen

Info

Publication number
ATE319703T1
ATE319703T1 AT02747793T AT02747793T ATE319703T1 AT E319703 T1 ATE319703 T1 AT E319703T1 AT 02747793 T AT02747793 T AT 02747793T AT 02747793 T AT02747793 T AT 02747793T AT E319703 T1 ATE319703 T1 AT E319703T1
Authority
AT
Austria
Prior art keywords
modulators
chemokine receptor
receptor activity
compounds suitable
piperidine compounds
Prior art date
Application number
AT02747793T
Other languages
German (de)
English (en)
Inventor
Richard Evans
Matthew Perry
Brian Springthorpe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0116179A external-priority patent/GB0116179D0/en
Priority claimed from GB0123037A external-priority patent/GB0123037D0/en
Application filed filed Critical
Application granted granted Critical
Publication of ATE319703T1 publication Critical patent/ATE319703T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
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  • Pain & Pain Management (AREA)
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  • Urology & Nephrology (AREA)
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  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
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AT02747793T 2001-07-02 2002-07-01 Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen ATE319703T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0116179A GB0116179D0 (en) 2001-07-02 2001-07-02 Chemical compounds
GB0123037A GB0123037D0 (en) 2001-09-25 2001-09-25 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE319703T1 true ATE319703T1 (de) 2006-03-15

Family

ID=26246268

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02747793T ATE319703T1 (de) 2001-07-02 2002-07-01 Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen

Country Status (25)

Country Link
US (1) US7307090B2 (enExample)
EP (2) EP1604982A1 (enExample)
JP (1) JP3857270B2 (enExample)
KR (1) KR20040013090A (enExample)
CN (1) CN1545509A (enExample)
AR (1) AR042401A1 (enExample)
AT (1) ATE319703T1 (enExample)
BR (1) BR0210733A (enExample)
CA (1) CA2452597A1 (enExample)
CO (1) CO5540307A2 (enExample)
CY (1) CY1106095T1 (enExample)
DE (1) DE60209736T2 (enExample)
DK (1) DK1404667T3 (enExample)
ES (1) ES2258642T3 (enExample)
HU (1) HUP0401886A2 (enExample)
IL (1) IL159256A0 (enExample)
IS (1) IS7094A (enExample)
MX (1) MXPA03011722A (enExample)
NO (1) NO20035729L (enExample)
NZ (1) NZ530202A (enExample)
PL (1) PL368041A1 (enExample)
PT (1) PT1404667E (enExample)
RU (1) RU2004100839A (enExample)
SA (1) SA02230184B1 (enExample)
WO (1) WO2003004487A1 (enExample)

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SE0300957D0 (sv) * 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
SE0302956D0 (sv) * 2003-11-07 2003-11-07 Astrazeneca Ab Chemical compounds
SE0400925D0 (sv) * 2004-04-06 2004-04-06 Astrazeneca Ab Chemical compounds
SE0403003D0 (sv) * 2004-12-09 2004-12-09 Astrazeneca Ab Chemical compound 1
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EP4585589A3 (en) 2008-12-03 2025-11-19 The Scripps Research Institute Stem cell cultures
CN108135168B (zh) 2015-05-21 2021-07-20 凯莫森特里克斯股份有限公司 Ccr2调节剂
AR112831A1 (es) 2017-09-25 2019-12-18 Chemocentryx Inc Terapia de combinación usando un antagonista del receptor 2 de quimiocina (ccr2) y un inhibidor de pd-1 / pd-l1
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CN112105353B (zh) 2018-01-08 2024-04-19 凯莫森特里克斯股份有限公司 Ccr2拮抗剂治疗实体瘤的方法
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JP3857270B2 (ja) 2006-12-13
DE60209736D1 (de) 2006-05-04
HUP0401886A2 (hu) 2004-12-28
HK1062559A1 (en) 2004-11-12
NO20035729D0 (no) 2003-12-19
PT1404667E (pt) 2006-07-31
CO5540307A2 (es) 2005-07-29
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EP1604982A1 (en) 2005-12-14
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AR042401A1 (es) 2005-06-22
US20040235894A1 (en) 2004-11-25
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