CN1537019A - 醛固酮受体拮抗剂和HMG CoA还原酶抑制剂的药物组合 - Google Patents
醛固酮受体拮抗剂和HMG CoA还原酶抑制剂的药物组合 Download PDFInfo
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- CN1537019A CN1537019A CNA028145577A CN02814557A CN1537019A CN 1537019 A CN1537019 A CN 1537019A CN A028145577 A CNA028145577 A CN A028145577A CN 02814557 A CN02814557 A CN 02814557A CN 1537019 A CN1537019 A CN 1537019A
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- hmg
- reductase inhibitor
- receptor antagonist
- aldosterone receptor
- eplerenone
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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| US30633601P | 2001-07-19 | 2001-07-19 | |
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| CN1537019A true CN1537019A (zh) | 2004-10-13 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106461636A (zh) * | 2014-01-10 | 2017-02-22 | 重症监护诊断股份有限公司 | 用于测定心力衰竭风险的方法和系统 |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003901812A0 (en) * | 2003-04-15 | 2003-05-01 | Vital Health Sciences Pty Ltd | Phosphates of secondary alcohols |
| WO2006012642A2 (en) * | 2004-07-30 | 2006-02-02 | Exelixis, Inc. | Pyrrole derivatives as pharmaceutical agents |
| EP1948600B1 (en) * | 2005-07-05 | 2014-04-16 | The President & Fellows Of Harvard College | Liver targeted conjugates |
| CN1310941C (zh) * | 2005-07-13 | 2007-04-18 | 南京大学 | 依普利酮的合成方法 |
| JP2009514851A (ja) * | 2005-11-08 | 2009-04-09 | ランバクシー ラボラトリーズ リミテッド | (3r,5r)−7−[2−(4−フルオロフェニル)−5−イソプロピル−3−フェニル−4−[(4−ヒドロキシメチルフェニルアミノ)カルボニル]−ピロール−1−イル]−3,5−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法 |
| GB0600967D0 (en) * | 2006-01-18 | 2006-03-01 | Imp Innovations Ltd | Methods |
| WO2007106862A2 (en) * | 2006-03-14 | 2007-09-20 | Kinemed, Inc. | The use of statins to stimulate neurogenesis |
| WO2008021666A2 (en) * | 2006-08-18 | 2008-02-21 | Morton Grove Pharmaceuticals, Inc. | Stable liquid levetiracetam compositions and methods |
| FR2917975B1 (fr) * | 2007-06-26 | 2009-10-16 | Ceva Sante Animale Sa | Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains |
| EP2135607A1 (en) | 2008-06-18 | 2009-12-23 | Pharnext | Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders |
| CN102316872B (zh) | 2008-11-26 | 2016-12-21 | 萨蒂奥根制药公司 | 治疗肥胖症和糖尿病的胆汁酸再循环抑制剂 |
| US9387206B2 (en) | 2009-11-03 | 2016-07-12 | Pharnext | Therapeutic approaches for treating Alzheimer's disease |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| JP5854476B2 (ja) * | 2009-11-30 | 2016-02-09 | アデア ファーマスーティカルズ,インコーポレイテッド | 圧縮性コーティングで被覆された医薬組成物及び錠剤並びに製造方法 |
| EP3593802A3 (en) | 2010-05-26 | 2020-03-25 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| US10010515B2 (en) | 2011-03-01 | 2018-07-03 | Pharnext | Therapeutic approaches for treating Parkinson's disease |
| US9241933B2 (en) | 2011-03-01 | 2016-01-26 | Pharnext | Compositions for treating amyotrophic lateral sclerosis |
| US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
| ES2665569T3 (es) | 2011-03-01 | 2018-04-26 | Pharnext | Tratamiento de la isquemia cerebral |
| DE102011015142A1 (de) * | 2011-03-17 | 2012-09-20 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Agens zur Prophylaxe und Behandlung altersassoziierter Krankheiten und Störungen sowie zur Verlängerung der Lebensdauer |
| WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| WO2013063526A1 (en) | 2011-10-28 | 2013-05-02 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease |
| EA030839B1 (ru) | 2011-10-28 | 2018-10-31 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
| CN105228615A (zh) | 2013-03-15 | 2016-01-06 | 鲁美纳医药公司 | 用于治疗巴雷特食管和胃食管返流疾病的胆汁酸再循环抑制剂 |
| JP2016514684A (ja) | 2013-03-15 | 2016-05-23 | ルメナ ファーマシューティカルズ エルエルシー | 原発性硬化性胆管炎および炎症性腸疾患の処置のための胆汁酸再循環阻害剤 |
| AU2020221834B2 (en) | 2019-02-12 | 2025-10-23 | Mirum Pharmaceuticals, Inc. | Genotype and dose-dependent response to an ASBTI in patients with bile salt export pump deficiency |
Family Cites Families (6)
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| DE69634054T2 (de) * | 1995-07-17 | 2005-12-08 | Warner-Lambert Co. | Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin) |
| NZ500141A (en) * | 1997-04-18 | 2002-05-31 | G | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
| GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
| US6638937B2 (en) * | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| AU4348200A (en) * | 1999-04-19 | 2000-11-02 | Regents Of The University Of Michigan, The | Compositions and methods for increasing the bioavailability of lactone ring containing drugs |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106461636A (zh) * | 2014-01-10 | 2017-02-22 | 重症监护诊断股份有限公司 | 用于测定心力衰竭风险的方法和系统 |
| CN113744876A (zh) * | 2014-01-10 | 2021-12-03 | 重症监护诊断股份有限公司 | 用于测定心力衰竭风险的方法和系统 |
Also Published As
| Publication number | Publication date |
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| CA2452678A1 (en) | 2003-01-30 |
| ATE363917T1 (de) | 2007-06-15 |
| EP1406660B1 (en) | 2007-06-06 |
| IL159588A0 (en) | 2004-06-01 |
| WO2003007993A1 (en) | 2003-01-30 |
| JP2004537553A (ja) | 2004-12-16 |
| ECSP044950A (es) | 2004-02-26 |
| OA12983A (en) | 2006-10-13 |
| DE60220522D1 (de) | 2007-07-19 |
| DE60220522T2 (de) | 2007-09-27 |
| ZA200400288B (en) | 2005-06-29 |
| MA27050A1 (fr) | 2004-12-20 |
| UA76475C2 (en) | 2006-08-15 |
| NO20040211L (no) | 2004-03-16 |
| TNSN04001A1 (fr) | 2006-06-01 |
| US20060003975A1 (en) | 2006-01-05 |
| MXPA04000586A (es) | 2004-04-20 |
| KR20040023660A (ko) | 2004-03-18 |
| US20030149010A1 (en) | 2003-08-07 |
| EP1406660A1 (en) | 2004-04-14 |
| PL367417A1 (en) | 2005-02-21 |
| AP2004002951A0 (en) | 2004-03-31 |
| EA200400029A1 (ru) | 2004-08-26 |
| CO5550464A2 (es) | 2005-08-31 |
| BR0211274A (pt) | 2004-08-03 |
| GEP20063811B (en) | 2006-05-10 |
| IS7093A (is) | 2003-12-23 |
| ES2286270T3 (es) | 2007-12-01 |
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