KR20040023660A - 알도스테론 수용체 길항제 및 hmg coa 환원효소억제제의 병용물 - Google Patents

알도스테론 수용체 길항제 및 hmg coa 환원효소억제제의 병용물 Download PDF

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Publication number
KR20040023660A
KR20040023660A KR10-2004-7000846A KR20047000846A KR20040023660A KR 20040023660 A KR20040023660 A KR 20040023660A KR 20047000846 A KR20047000846 A KR 20047000846A KR 20040023660 A KR20040023660 A KR 20040023660A
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South Korea
Prior art keywords
hmg
reductase inhibitor
receptor antagonist
aldosterone receptor
eplerenone
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR10-2004-7000846A
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English (en)
Korean (ko)
Inventor
브래들리 티. 켈러
엘렌 지. 맥마혼
리카르도 로샤
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파마시아 코포레이션
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Publication of KR20040023660A publication Critical patent/KR20040023660A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
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    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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  • Rheumatology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
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  • Obesity (AREA)
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  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Addiction (AREA)
KR10-2004-7000846A 2001-07-19 2002-07-18 알도스테론 수용체 길항제 및 hmg coa 환원효소억제제의 병용물 Ceased KR20040023660A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30633601P 2001-07-19 2001-07-19
US60/306,336 2001-07-19
PCT/US2002/022896 WO2003007993A1 (en) 2001-07-19 2002-07-18 Combination of an aldosterone receptor antagonist and an hmg coa reductase inhibitor

Publications (1)

Publication Number Publication Date
KR20040023660A true KR20040023660A (ko) 2004-03-18

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KR10-2004-7000846A Ceased KR20040023660A (ko) 2001-07-19 2002-07-18 알도스테론 수용체 길항제 및 hmg coa 환원효소억제제의 병용물

Country Status (26)

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US (2) US20030149010A1 (enExample)
EP (1) EP1406660B1 (enExample)
JP (1) JP2004537553A (enExample)
KR (1) KR20040023660A (enExample)
CN (1) CN1537019A (enExample)
AP (1) AP2004002951A0 (enExample)
AT (1) ATE363917T1 (enExample)
BR (1) BR0211274A (enExample)
CA (1) CA2452678A1 (enExample)
CO (1) CO5550464A2 (enExample)
DE (1) DE60220522T2 (enExample)
EA (1) EA200400029A1 (enExample)
EC (1) ECSP044950A (enExample)
ES (1) ES2286270T3 (enExample)
GE (1) GEP20063811B (enExample)
IL (1) IL159588A0 (enExample)
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MA (1) MA27050A1 (enExample)
MX (1) MXPA04000586A (enExample)
NO (1) NO20040211L (enExample)
OA (1) OA12983A (enExample)
PL (1) PL367417A1 (enExample)
TN (1) TNSN04001A1 (enExample)
UA (1) UA76475C2 (enExample)
WO (1) WO2003007993A1 (enExample)
ZA (1) ZA200400288B (enExample)

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EP2135607A1 (en) 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
WO2010062861A2 (en) 2008-11-26 2010-06-03 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of obesity and diabetes
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EP2322163A1 (en) * 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
JP5854476B2 (ja) * 2009-11-30 2016-02-09 アデア ファーマスーティカルズ,インコーポレイテッド 圧縮性コーティングで被覆された医薬組成物及び錠剤並びに製造方法
EP4137137A1 (en) 2010-05-26 2023-02-22 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
US8877221B2 (en) 2010-10-27 2014-11-04 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same
US9107983B2 (en) 2010-10-27 2015-08-18 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising statins
US9241933B2 (en) 2011-03-01 2016-01-26 Pharnext Compositions for treating amyotrophic lateral sclerosis
HUE038653T2 (hu) 2011-03-01 2018-11-28 Pharnext Neurológiai rendellenességek baclofen és acamprosate alapú terápiája
US10010515B2 (en) 2011-03-01 2018-07-03 Pharnext Therapeutic approaches for treating Parkinson's disease
US9248111B2 (en) 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
DE102011015142A1 (de) * 2011-03-17 2012-09-20 Eberhard-Karls-Universität Tübingen Universitätsklinikum Agens zur Prophylaxe und Behandlung altersassoziierter Krankheiten und Störungen sowie zur Verlängerung der Lebensdauer
WO2012170417A2 (en) 2011-06-06 2012-12-13 Warsaw Orthopedic, Inc. Methods and compositions to enhance bone growth comprising a statin
WO2013063512A1 (en) 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
MX363161B (es) 2011-10-28 2019-03-13 Lumena Pharmaceuticals Inc Inhibidores de la recirculación de ácidos biliares para el tratamiento de hipercolemia y enfermedad hepática colestásica.
MX2015013196A (es) 2013-03-15 2016-04-15 Lumena Pharmaceuticals Inc Inhibidores de reciclaje de acidos biliares para el tratamiento de la enfermedad de reflujo gastroesofagico y esofago de barrett.
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AU2015204675A1 (en) * 2014-01-10 2016-07-28 Critical Care Diagnostics, Inc. Methods and systems for determining risk of heart failure
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DE60220522D1 (de) 2007-07-19
EP1406660A1 (en) 2004-04-14
IL159588A0 (en) 2004-06-01
ATE363917T1 (de) 2007-06-15
NO20040211L (no) 2004-03-16
JP2004537553A (ja) 2004-12-16
BR0211274A (pt) 2004-08-03
OA12983A (en) 2006-10-13
DE60220522T2 (de) 2007-09-27
ES2286270T3 (es) 2007-12-01
MA27050A1 (fr) 2004-12-20
CN1537019A (zh) 2004-10-13
US20030149010A1 (en) 2003-08-07
US20060003975A1 (en) 2006-01-05
IS7093A (is) 2003-12-23
WO2003007993A1 (en) 2003-01-30
EP1406660B1 (en) 2007-06-06
PL367417A1 (en) 2005-02-21
CA2452678A1 (en) 2003-01-30
EA200400029A1 (ru) 2004-08-26
AP2004002951A0 (en) 2004-03-31
GEP20063811B (en) 2006-05-10
CO5550464A2 (es) 2005-08-31
TNSN04001A1 (fr) 2006-06-01
UA76475C2 (en) 2006-08-15
MXPA04000586A (es) 2004-04-20
ZA200400288B (en) 2005-06-29
ECSP044950A (es) 2004-02-26

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