CN1432569A - 吡唑衍生物的制备方法 - Google Patents
吡唑衍生物的制备方法 Download PDFInfo
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- CN1432569A CN1432569A CN02143826A CN02143826A CN1432569A CN 1432569 A CN1432569 A CN 1432569A CN 02143826 A CN02143826 A CN 02143826A CN 02143826 A CN02143826 A CN 02143826A CN 1432569 A CN1432569 A CN 1432569A
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- alkyl
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
- C07C255/65—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/30—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Ar | X | R3 | R4 | R5 | R6 | |
2,6-Cl2-4-CF3Ph | HSO4 | COCH3 | SO2(4-ClPh) | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | SO2(4-ClPh) | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | CO2Et | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-OCF3Ph | Cl | Cl | SOCF3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | SOEt | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | P(O)(OEt)2 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | Cl | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | SO(4-ClPh) | COCH3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | COCF3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | NO2 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | NO2 | COCH3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | SO2(2-噻吩基) | COCH3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | COCH3 | SO2(2-噻吩基) | CN | NH2 | |
2,6-Cl2-4-(4-ClPh)Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | Br | COCH3 | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | Br | COPh | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | CO(2-呋喃基) | CN | NH2 | |
2,6-Cl2-4-CF3Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | COCH3 | SO2(4-ClPh) | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | SO2(4-ClPh) | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | CO2Et | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | SOCH3 | CN | NH2 | |
2,6-Cl2-4-SF3Ph | Cl | Cl | SOCF3 | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | SOEt | CN | NH2 | |
2,6-Cl2-4-SF3Ph | HSO4 | CN | P(O)(OEt) | CN | NH2 | |
2,6-Cl2-4-(4CF3Ph)Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-(4-OCF3Ph)Ph | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-OPh | HSO4 | CN | SOCF3 | CN | NH2 | |
2,6-Cl2-4-(4-SCF3Ph)Ph | HSO4 | CN | SOCF3 | CN | NH2 |
Claims (6)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/815,848 US5907041A (en) | 1997-03-12 | 1997-03-12 | Process for preparing pyrazole derivatives |
US815,848 | 1997-03-12 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98803283A Division CN1107672C (zh) | 1997-03-12 | 1998-03-05 | 用于制备吡唑衍生物的中间体 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1432569A true CN1432569A (zh) | 2003-07-30 |
CN1184206C CN1184206C (zh) | 2005-01-12 |
Family
ID=25219006
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98803283A Expired - Lifetime CN1107672C (zh) | 1997-03-12 | 1998-03-05 | 用于制备吡唑衍生物的中间体 |
CNB021438269A Expired - Lifetime CN1184206C (zh) | 1997-03-12 | 1998-03-05 | 吡唑衍生物的制备方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98803283A Expired - Lifetime CN1107672C (zh) | 1997-03-12 | 1998-03-05 | 用于制备吡唑衍生物的中间体 |
Country Status (25)
Country | Link |
---|---|
US (2) | US5907041A (zh) |
EP (1) | EP0966444B1 (zh) |
JP (1) | JP4429389B2 (zh) |
KR (1) | KR100536795B1 (zh) |
CN (2) | CN1107672C (zh) |
AR (1) | AR015108A1 (zh) |
AT (1) | ATE223382T1 (zh) |
AU (1) | AU750836B2 (zh) |
BG (1) | BG64648B1 (zh) |
BR (1) | BR9808854B1 (zh) |
CA (1) | CA2283507C (zh) |
CZ (1) | CZ296302B6 (zh) |
DE (1) | DE69807660T2 (zh) |
DK (1) | DK0966444T3 (zh) |
EA (1) | EA002086B1 (zh) |
ES (1) | ES2179476T3 (zh) |
HU (1) | HU229879B1 (zh) |
ID (1) | ID23447A (zh) |
IL (1) | IL131856A0 (zh) |
NZ (1) | NZ337766A (zh) |
PL (1) | PL196442B1 (zh) |
SK (1) | SK284800B6 (zh) |
TR (1) | TR199902213T2 (zh) |
WO (1) | WO1998040358A1 (zh) |
ZA (1) | ZA981875B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111592510A (zh) * | 2020-04-26 | 2020-08-28 | 衡水均凯化工有限公司 | 一种4,4-(六氟亚异丙烯基)二邻二甲酸酐的合成方法 |
CN111592511A (zh) * | 2020-04-26 | 2020-08-28 | 衡水均凯化工有限公司 | 一种4,4-(六氟亚异丙烯基)二邻二甲酸酐的制备工艺 |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9907458D0 (en) * | 1999-03-31 | 1999-05-26 | Rhone Poulenc Agrochimie | Processes for preparing pesticidal intermediates |
EP1264823A1 (en) * | 2001-06-08 | 2002-12-11 | Novartis AG | Process for the preparation of 2,3-dicyanopropionates |
WO2005023773A1 (en) * | 2003-09-04 | 2005-03-17 | Pfizer Limited | Process for the preparation of substituted aryl pyrazoles |
US7541357B2 (en) | 2004-07-15 | 2009-06-02 | Amr Technology, Inc. | Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
GEP20125566B (en) | 2005-07-15 | 2012-07-10 | Amr Technology Inc | Aryl-and heteroaryl-substituded tetrahydro-benzazepines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
CN102458123A (zh) | 2009-05-12 | 2012-05-16 | 阿尔巴尼分子研究公司 | 芳基、杂芳基和杂环取代的四氢异喹啉及其用途 |
WO2010132487A1 (en) | 2009-05-12 | 2010-11-18 | Bristol-Myers Squibb Company | CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF |
WO2012089516A1 (en) * | 2010-12-30 | 2012-07-05 | Basf Se | Surface-modified pigment preparations |
CN111825653A (zh) | 2019-04-19 | 2020-10-27 | 安道麦马克西姆有限公司 | 取代吡唑类化合物的制备及其作为邻氨基苯甲酰胺前体的用途 |
CN110483480A (zh) * | 2019-09-11 | 2019-11-22 | 江苏优普生物化学科技股份有限公司 | 2-(3-氯吡啶-2-基)-5-羟基-3-吡唑烷甲酸乙酯的合成方法 |
CN110981806A (zh) * | 2019-12-06 | 2020-04-10 | 江苏优普生物化学科技股份有限公司 | 合成芳基吡唑腈副产碳酸二酯的方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3140226A (en) * | 1957-05-01 | 1964-07-07 | Monsanto Co | Microorganism toxic alpha-chloro-betacyanoethylaryl sulfones |
US2978480A (en) * | 1957-05-08 | 1961-04-04 | Du Pont | Bis-(alkyl sulfonyl and sulfoxyl) aliphatic acid derivatives |
DE2928136A1 (de) * | 1979-07-12 | 1981-01-29 | Bayer Ag | Phosphorhaltige azoverbindungen sowie deren herstellung und verwendung als schaedlingsbekaempfungsmittel, lichtempfindliche materialien und als ausgangsstoffe zur synthese von pyrazolonen |
GB8531485D0 (en) * | 1985-12-20 | 1986-02-05 | May & Baker Ltd | Compositions of matter |
GB8713768D0 (en) * | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
US5232940A (en) * | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
DE3602524A1 (de) * | 1986-01-29 | 1987-07-30 | Bayer Ag | Verfahren zur herstellung konzentrierter loesungen von anionischen farbstoffen |
US4918085A (en) * | 1989-03-02 | 1990-04-17 | Rhone-Poulenc Ag Company | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles, compositions and use |
GB8913866D0 (en) * | 1989-06-16 | 1989-08-02 | May & Baker Ltd | New compositions of matter |
US5236938A (en) * | 1991-04-30 | 1993-08-17 | Rhone-Poulenc Inc. | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles |
GB9120641D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Heterocyclic compounds |
GB9306184D0 (en) * | 1993-03-25 | 1993-05-19 | Zeneca Ltd | Heteroaromatic compounds |
DE19511269A1 (de) * | 1994-03-30 | 1995-10-05 | Ciba Geigy Ag | Pyrazole |
DE4414333A1 (de) * | 1994-04-25 | 1995-10-26 | Bayer Ag | Substituierte Pyridylpyrazole |
-
1997
- 1997-03-12 US US08/815,848 patent/US5907041A/en not_active Expired - Lifetime
-
1998
- 1998-03-05 WO PCT/EP1998/001226 patent/WO1998040358A1/en active IP Right Grant
- 1998-03-05 ES ES98913641T patent/ES2179476T3/es not_active Expired - Lifetime
- 1998-03-05 CZ CZ0319799A patent/CZ296302B6/cs not_active IP Right Cessation
- 1998-03-05 IL IL13185698A patent/IL131856A0/xx not_active IP Right Cessation
- 1998-03-05 TR TR1999/02213T patent/TR199902213T2/xx unknown
- 1998-03-05 DK DK98913641T patent/DK0966444T3/da active
- 1998-03-05 AU AU68270/98A patent/AU750836B2/en not_active Expired
- 1998-03-05 HU HU0002931A patent/HU229879B1/hu unknown
- 1998-03-05 AT AT98913641T patent/ATE223382T1/de not_active IP Right Cessation
- 1998-03-05 JP JP53917298A patent/JP4429389B2/ja not_active Expired - Lifetime
- 1998-03-05 DE DE69807660T patent/DE69807660T2/de not_active Expired - Lifetime
- 1998-03-05 CA CA002283507A patent/CA2283507C/en not_active Expired - Lifetime
- 1998-03-05 KR KR10-1999-7008197A patent/KR100536795B1/ko not_active IP Right Cessation
- 1998-03-05 EA EA199900821A patent/EA002086B1/ru not_active IP Right Cessation
- 1998-03-05 SK SK1231-99A patent/SK284800B6/sk not_active IP Right Cessation
- 1998-03-05 PL PL335610A patent/PL196442B1/pl unknown
- 1998-03-05 ZA ZA981875A patent/ZA981875B/xx unknown
- 1998-03-05 CN CN98803283A patent/CN1107672C/zh not_active Expired - Lifetime
- 1998-03-05 EP EP98913641A patent/EP0966444B1/en not_active Expired - Lifetime
- 1998-03-05 NZ NZ337766A patent/NZ337766A/xx not_active IP Right Cessation
- 1998-03-05 BR BRPI9808854-8A patent/BR9808854B1/pt not_active IP Right Cessation
- 1998-03-05 CN CNB021438269A patent/CN1184206C/zh not_active Expired - Lifetime
- 1998-03-05 ID IDW991018A patent/ID23447A/id unknown
- 1998-03-10 AR ARP980101070A patent/AR015108A1/es active IP Right Grant
-
1999
- 1999-02-16 US US09/249,798 patent/US6090927A/en not_active Expired - Lifetime
- 1999-10-04 BG BG103778A patent/BG64648B1/bg unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111592510A (zh) * | 2020-04-26 | 2020-08-28 | 衡水均凯化工有限公司 | 一种4,4-(六氟亚异丙烯基)二邻二甲酸酐的合成方法 |
CN111592511A (zh) * | 2020-04-26 | 2020-08-28 | 衡水均凯化工有限公司 | 一种4,4-(六氟亚异丙烯基)二邻二甲酸酐的制备工艺 |
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