CN1262625A - 乳铁蛋白在治疗过敏原诱发疾病中的应用 - Google Patents

乳铁蛋白在治疗过敏原诱发疾病中的应用 Download PDF

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Publication number
CN1262625A
CN1262625A CN98805584A CN98805584A CN1262625A CN 1262625 A CN1262625 A CN 1262625A CN 98805584 A CN98805584 A CN 98805584A CN 98805584 A CN98805584 A CN 98805584A CN 1262625 A CN1262625 A CN 1262625A
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CN
China
Prior art keywords
lactoferrin
inflammatory disease
tnf
induced
skin
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Pending
Application number
CN98805584A
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English (en)
Chinese (zh)
Inventor
I·金伯
M·坎伯巴奇
R·J·迪尔曼
O·M·康萘利
P·沃德
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Agennix Inc
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Agennix Inc
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Publication of CN1262625A publication Critical patent/CN1262625A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN98805584A 1997-04-10 1998-04-10 乳铁蛋白在治疗过敏原诱发疾病中的应用 Pending CN1262625A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4189097P 1997-04-10 1997-04-10
US60/041,890 1997-04-10

Publications (1)

Publication Number Publication Date
CN1262625A true CN1262625A (zh) 2000-08-09

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ID=21918897

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98805584A Pending CN1262625A (zh) 1997-04-10 1998-04-10 乳铁蛋白在治疗过敏原诱发疾病中的应用

Country Status (12)

Country Link
US (1) US20030190303A1 (enExample)
EP (1) EP0979099B1 (enExample)
JP (1) JP2001519815A (enExample)
CN (1) CN1262625A (enExample)
AT (1) ATE297755T1 (enExample)
AU (1) AU747385C (enExample)
CA (1) CA2285960A1 (enExample)
DE (1) DE69830582T2 (enExample)
ES (1) ES2245028T3 (enExample)
IL (1) IL132293A0 (enExample)
NZ (1) NZ500712A (enExample)
WO (1) WO1998044940A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100467059C (zh) * 2002-05-10 2009-03-11 阿根尼克斯有限公司 乳铁蛋白在治疗恶性肿瘤疾病中的用途
CN102370964A (zh) * 2010-08-16 2012-03-14 李兴德 白细胞介素受体拮抗蛋白在制备皮肤外用制剂中的应用
CN103002907A (zh) * 2010-04-23 2013-03-27 普若拜特有限公司 湿疹治疗
CN112074291A (zh) * 2018-02-07 2020-12-11 耐伊洛斯有限责任公司 预防和治疗呼吸道疾病的组合物
CN114867368A (zh) * 2019-12-11 2022-08-05 N·V·努特里奇亚 用于提高免疫适宜的营养组合物

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050076A1 (en) * 1997-05-03 1998-11-12 Board Of Regents, The University Of Texas System Methods for preventing and treating the insult-induced metabolic imbalance in humans and other animals
US6399570B1 (en) * 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
CN100384472C (zh) * 2000-01-14 2008-04-30 明治乳业株式会社 抗原特异性IgE抗体产生抑制剂
RU2165769C1 (ru) * 2000-07-13 2001-04-27 Якубовская Раиса Ивановна Антибактериальный, антиоксидантный, иммуномодулирующий и антиканцерогенный препарат и способ его применения
DK2270052T3 (en) 2001-06-26 2018-07-02 Amgen Inc Antibodies to OPGL
JP3668241B2 (ja) * 2001-12-28 2005-07-06 株式会社Nrlファーマ 脂質代謝改善用組成物
JP3806427B2 (ja) * 2002-01-21 2006-08-09 株式会社Nrlファーマ 新規鎮痛剤
WO2003099207A2 (en) 2002-05-24 2003-12-04 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
NZ566539A (en) 2002-09-06 2010-01-29 Medarex Inc Therapeutic human anti-IL-1R1 monoclonal antibody
DE60335997D1 (de) * 2002-09-16 2011-03-24 Agennix Inc Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus
US20040152624A1 (en) * 2002-12-06 2004-08-05 Atul Varadhachary Oral lactoferrin in the treatment of sepsis
US7592306B2 (en) 2002-12-10 2009-09-22 Agennix, Inc. Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8105615B2 (en) * 2003-06-06 2012-01-31 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
US20050075277A1 (en) * 2003-07-10 2005-04-07 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
US20090203586A1 (en) * 2004-06-11 2009-08-13 Syngenta Limited Method for ameliorating an inflammatory skin condition
WO2006047744A2 (en) 2004-10-26 2006-05-04 Agennix Incorporated Compositions of lactoferrin related peptides and uses thereof
WO2006098625A1 (en) 2005-03-15 2006-09-21 Campina Nederland Holding B.V. Dermatologic use of milk proteins
US8178486B2 (en) * 2005-07-21 2012-05-15 Animal Technology Institute Taiwan Method for promoting hair growth
AU2006300009A1 (en) * 2005-10-14 2007-04-19 Auckland Uniservices Limited Use of lactoferrin fragments and hydrolysates
EP1952818A4 (en) * 2005-10-27 2009-10-21 Sunstar Inc OSTEOCLASTICIZATION PREPARATION, ORAL AGGREGATION AND PROPHYLACTIC OR THERAPEUTIC AGENT AGAINST BONE DISEASES WITH LACTOFERRIN-CONTAINING LIPOSOME
WO2020035482A1 (en) 2018-08-13 2020-02-20 Iltoo Pharma Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
WO2023222565A1 (en) 2022-05-16 2023-11-23 Institut National de la Santé et de la Recherche Médicale Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation
CN115737787B (zh) * 2022-12-15 2024-04-19 四川大学 乳铁蛋白联合胆碱在制备预防和/或治疗阿尔兹海默症的药物中的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641696B2 (fr) * 1986-04-11 1991-03-08 Sederma Sa Utilisation d'un melange renfermant de la lactoferrine dans des preparations cosmetiques anti-radicaux libres
FR2596986B1 (fr) * 1986-04-11 1988-09-23 Sederma Sa Utilisation de la lactoferrine dans des preparations cosmetiques, antiradicaux libres
FR2685202B1 (fr) * 1991-12-24 1995-03-24 Sederma Sa Nouvelle methode de traitement pharmaceutique et cosmetique pour la regulation de la seborrhee, de l'acne et de la flore cutanee.
JP3184923B2 (ja) * 1992-01-08 2001-07-09 ビオ セレ ラボラトワール エス ア 抗リウマチ剤
JPH05279266A (ja) * 1992-04-02 1993-10-26 Imuno Japan:Kk 歯周病の治療・予防用医薬組成物
JP3163171B2 (ja) * 1992-07-15 2001-05-08 森永乳業株式会社 IgA産生促進剤
JP3746081B2 (ja) * 1994-02-24 2006-02-15 森永乳業株式会社 動物皮膚病治療剤
JPH0859450A (ja) * 1994-08-18 1996-03-05 Kose Corp 皮膚外用剤
JP2832517B2 (ja) * 1994-12-09 1998-12-09 雪印乳業株式会社 大腸菌付着阻止剤
JP3911642B2 (ja) * 1995-06-06 2007-05-09 株式会社加美乃素本舗 皮膚外用剤
JP3888707B2 (ja) * 1996-01-22 2007-03-07 森永乳業株式会社 血管新生病治療剤
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100467059C (zh) * 2002-05-10 2009-03-11 阿根尼克斯有限公司 乳铁蛋白在治疗恶性肿瘤疾病中的用途
CN100467060C (zh) * 2002-05-10 2009-03-11 阿根尼克斯有限公司 通过瘤内施用乳铁蛋白治疗恶性肿瘤疾病的用途
CN103002907A (zh) * 2010-04-23 2013-03-27 普若拜特有限公司 湿疹治疗
CN102370964A (zh) * 2010-08-16 2012-03-14 李兴德 白细胞介素受体拮抗蛋白在制备皮肤外用制剂中的应用
CN102370964B (zh) * 2010-08-16 2015-12-09 李兴德 白细胞介素受体拮抗蛋白在制备皮肤外用制剂中的应用
CN112074291A (zh) * 2018-02-07 2020-12-11 耐伊洛斯有限责任公司 预防和治疗呼吸道疾病的组合物
CN114867368A (zh) * 2019-12-11 2022-08-05 N·V·努特里奇亚 用于提高免疫适宜的营养组合物

Also Published As

Publication number Publication date
AU747385B2 (en) 2002-05-16
EP0979099A1 (en) 2000-02-16
IL132293A0 (en) 2001-03-19
WO1998044940A1 (en) 1998-10-15
DE69830582T2 (de) 2006-05-04
AU747385C (en) 2003-01-30
ATE297755T1 (de) 2005-07-15
ES2245028T3 (es) 2005-12-16
NZ500712A (en) 2002-10-25
CA2285960A1 (en) 1998-10-15
JP2001519815A (ja) 2001-10-23
DE69830582D1 (de) 2005-07-21
US20030190303A1 (en) 2003-10-09
EP0979099B1 (en) 2005-06-15
AU6964798A (en) 1998-10-30

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